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lanky
Well-known member
[3,2-c]pyrazole-5alpha-etioallocholane-17beta-tetrahydropyranol...............................................................................................sounds interesting....prostanozol
First prohormone wih pyrazole ring....a little worried about thp ether though..........$34 at dps nutrition........................another company is comming out with basicly 7a-Methylandrost-1-ene-3b-ol-17-one (Methyl 1-AD)......huh,, 3 beta hydroxy,,,there is ketone on C-17....i dont like the conversion kinetics on this one at all.....in the words of PATRICK ARNOLD himself
"why they made it a 3beta-ol, 17-one is beyond me
with that structure it requires two metabolic steps to get to the active compound - 7alpha-methyl-1-test
why not just sell 7alpha-methyl-1-test?
I can see their logic (or, more accurate illogic). The same logic seen with someone robbing a bank and only taking 20,000 dolllars when they could take 100,000. I guess they think they will be "cut a break" cuz its less illegal.
But anyway, whether 7alpha-methyl-1-test is an active compound is not known. I will say that there is a decent chance that it is a pretty potent steroid, but you just dunno till you test it"(that segment in quotes was from patrick arnold )
My interpretation/rant on the chemical structure itself
1--i agree with Mr. Arnold about why they just dont make 7 alpha methyl 1-testosterone.....of course dosing of 17alpha methyl 1-Test was about 10 mg per capsule(correct me if im wrong), Though 7 alpha methyl should not slow oxidation of 17 beta OH significantly,,so higher dosage should be required on oral administration,,,,The kinetics of 7 alpha methyl 19 nortestosterone suggests that 7 alpha methyl provides steric hindrance from alpha and beta of 5AR( this is why nandrolone deconate along with no carbon # 19 shown no 5 ar reduction disproving the theory that nandrolone mixed with finasteride causes greater hairloss.the structure is a poor substrate for 5-AR. Could finasteride cause hirloss through some other mechanism other than 5-AR...possibly when taking finasteride with 7 alpha methyl 19 nortestosterone the 17 Hydroxysteroid dehydrogenase becomes overloaded and and cant deactivate nandrolone by turning it into 17-keto nor derivitive of test . i repeat no DHN has been shown in human studieds including higher than a pharmacological dose... that was my little rant about the anabolic board....though 1-Test is already reduced hence no delta 4 -ene,,,will this 7-alpha methyl increase albumin binding?, shbg binding?,,,,no one realy has an answer for these things because there has been no studies,,,we can only speculate based on similar structures which is not valid ....sorry for the long post...just a little frustrated
First prohormone wih pyrazole ring....a little worried about thp ether though..........$34 at dps nutrition........................another company is comming out with basicly 7a-Methylandrost-1-ene-3b-ol-17-one (Methyl 1-AD)......huh,, 3 beta hydroxy,,,there is ketone on C-17....i dont like the conversion kinetics on this one at all.....in the words of PATRICK ARNOLD himself
"why they made it a 3beta-ol, 17-one is beyond me
with that structure it requires two metabolic steps to get to the active compound - 7alpha-methyl-1-test
why not just sell 7alpha-methyl-1-test?
I can see their logic (or, more accurate illogic). The same logic seen with someone robbing a bank and only taking 20,000 dolllars when they could take 100,000. I guess they think they will be "cut a break" cuz its less illegal.
But anyway, whether 7alpha-methyl-1-test is an active compound is not known. I will say that there is a decent chance that it is a pretty potent steroid, but you just dunno till you test it"(that segment in quotes was from patrick arnold )
My interpretation/rant on the chemical structure itself
1--i agree with Mr. Arnold about why they just dont make 7 alpha methyl 1-testosterone.....of course dosing of 17alpha methyl 1-Test was about 10 mg per capsule(correct me if im wrong), Though 7 alpha methyl should not slow oxidation of 17 beta OH significantly,,so higher dosage should be required on oral administration,,,,The kinetics of 7 alpha methyl 19 nortestosterone suggests that 7 alpha methyl provides steric hindrance from alpha and beta of 5AR( this is why nandrolone deconate along with no carbon # 19 shown no 5 ar reduction disproving the theory that nandrolone mixed with finasteride causes greater hairloss.the structure is a poor substrate for 5-AR. Could finasteride cause hirloss through some other mechanism other than 5-AR...possibly when taking finasteride with 7 alpha methyl 19 nortestosterone the 17 Hydroxysteroid dehydrogenase becomes overloaded and and cant deactivate nandrolone by turning it into 17-keto nor derivitive of test . i repeat no DHN has been shown in human studieds including higher than a pharmacological dose... that was my little rant about the anabolic board....though 1-Test is already reduced hence no delta 4 -ene,,,will this 7-alpha methyl increase albumin binding?, shbg binding?,,,,no one realy has an answer for these things because there has been no studies,,,we can only speculate based on similar structures which is not valid ....sorry for the long post...just a little frustrated
