Fluticasone propionate is a synthetic steroid of the glucocorticoid family. The naturally-occurring hormone, cortisol or hydrocortisone, is produced by the adrenal glands. Glucocorticoid steroids have potent anti-inflammatory actions. When used as a nasal inhaler or spray, the medication goes directly to the inside lining of the nose, and very little is absorbed into the rest of the body.