i go 2x/week with everything that is long lasting. just alternate...left butt cheek...right butt cheek...etc. like evander said, i too get zitts if i go longer because of the unbalanced levels. i'm currently in my 8th week of a DECA/EQ cycle @300mg/wk DECA and 500mg/wk EQ split sunday morning and wednesday evening and haven't seen any zitts at all.