The only difference betweem the two, other than ONE having a bit more 1-test per serving, is the inclusion of 4-AD in ONE+. The primary thing this is going to do that could not be provided by an equipotent amount of 1-test, is to provide estrogen. This will have a number of effects.
First, it will cause some fluid retention, which will not only increase strength, but it should ultimately lead to greater muscle growth, because hypertrophy is all about tension overload on the muscle fiber. It might directly aid protein synthesis by increasing cell volume. Estrogen also more directly aids muscle building by increasing androgen receptor density, increasing growth hormone and IGF-1 levels, and enhancing glucose utilization by the muscle.
The precense of estrogen is also necessary for the manifestation of many of effects normally associated with androgen use, such as increases in CNS stimulation/strength, libido, and aggression. Due to their lack of aromatization, and the fact that they suppress natural test (thus, estrogen), users of 1-AD, and 1-test by itself, actually experience as decrease in these areas rather than an increase.
Thus, I think it is definitely advantageous on a bulking cycle.
On the flip side, estrogen also causes some effects that one might prefer to avoid. As mentioned, it causes water retention (though, the amount from 4-AD is in the 3-4 lb range, rather than the 10+ one might get from a testosterone ester). In addition, it can also cause increases in body fat. Thus, ONE is probably the product of choice if you are dieting.
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