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ONCE AND FOR ALL: best anti-e

bigbench

New member
ok guys, I know that everyone has their own personal opinion on this, but I want to know what everyone feels works the best :arimidex, l-dex, femera, nolva.... Let's go ahead and settle this dipute. Also, the more facts we can use the better!

Also- is Bromo the best for prolactin?



Bigbench
 
Letrozole is working wonders for me, its my new best friend.
 
You can't really compare Nolvadex to the others. It's in a different category. Sure it effects estrogen but not in the same way Femara/anastrozole/aromasin does. Nolvadex will always have it's place in helping gyno symptoms.
 
have any of you guys noticed any fat loss while on these (from estrogen realted fat)? Just curios cause I need to loose a little fat of the love handles and chest
 
Damn Liquidex was working so well for me I never even looked into femara. How much are you guys paying?
 
firstenrgy said:

femera blows arimidex out, so far nothing else even comes close

although have not tried aromasin yet, but with femera there seems to be no need for it
 
Gambler said:
Any internet pharmacy's sell Femara?
i know one in Spain. i think they export to the US and since anti-e are not a controlled substance, you will be safe. Femara goes for ~200$/28 tabs @ 2.5mg and it the original product from Novartis. There are cheaper generic versions in the US available though.
 
HUCKLEBERRY FINNaplex said:
Absolutely.I use them while cutting for that very purpose,to manipulate A2/estrogen.
then, where is the flaw in this study?


J Clin Endocrinol Metab 2000 Jul;85(7):2370-7 Books, LinkOut


Comment in:
J Clin Endocrinol Metab. 2001 Apr;86(4):1836-8.

Estrogen suppression in males: metabolic effects.

Mauras N, O'Brien KO, Klein KO, Hayes V.

Nemours Research Programs at the Nemours Children's Clinic, Jacksonville, Florida 32207, USA. [email protected]

We have shown that testosterone (T) deficiency per se is associated with marked catabolic effects on protein, calcium metabolism, and body composition in men independent of changes in GH or insulin-like growth factor I production. It is not clear,,however, whether estrogens have a major role in whole body anabolism in males. We investigated the metabolic effects of selective estrogen suppression in the male using a potent aromatase inhibitor, Arimidex (Anastrozole). First, a dose-response study of 12 males (mean age, 16.1 +/- 0.3 yr) was conducted, and blood withdrawn at baseline and after 10 days of oral Arimidex given as two different doses (either 0.5 or 1 mg) in random order with a 14-day washout in between. A sensitive estradiol (E2) assay showed an approximately 50% decrease in E2 concentrations with either of the two doses; hence, a 1-mg dose was selected for other studies. Subsequently, eight males (aged 15-22 yr; four adults and four late pubertal) had isotopic infusions of [(13)C]leucine and (42)Ca/(44)Ca, indirect calorimetry, dual energy x-ray absorptiometry, isokinetic dynamometry, and growth factors measurements performed before and after 10 weeks of daily doses of Arimidex. Contrary to the effects of T withdrawal, there were no significant changes in body composition (body mass index, fat mass, and fat-free mass) after estrogen suppression or in rates of protein synthesis or degradation; carbohydrate, lipid, or protein oxidation; muscle strength; calcium kinetics; or bone growth factors concentrations. However, E2 concentrations decreased 48% (P = 0.006), with no significant change in mean and peak GH concentrations, but with an 18% decrease in plasma insulin-like growth factor I concentrations. There was a 58% increase in serum T (P = 0.0001), sex hormone-binding globulin did not change, whereas LH and FSH concentrations increased (P < 0.02, both). Serum bone markers, osteocalcin and bone alkaline phosphatase concentrations, and rates of bone calcium deposition and resorption did not change. In conclusion, these data suggest that in the male 1) estrogens do not contribute significantly to the changes in body composition and protein synthesis observed with changing androgen levels; 2) estrogen is a main regulator of the gonadal-pituitary feedback for the gonadotropin axis; and 3) this level of aromatase inhibition does not negatively impact either kinetically measured rates of bone calcium turnover or indirect markers of bone calcium turnover, at least in the short term. Further studies will provide valuable information on whether timed aromatase inhibition can be useful in increasing the height potential of pubertal boys with profound growth retardation without the confounding negative effects of gonadal androgen suppression.

:confused:
 
There´s a flaw

@punschkrapfen:

Yes, there´s definitely a major flaw in the study you presented: None of the male subjects did any weight training, they did not restrict caloric intake, they did not take a specific A2 Agonist like Yohimbine, nor did they take any fatburners. Major flaw!

@all: I´m new here, in a few upcoming post i will intrdoduce
myself, post my cycle and ask some questions, since the
knowledge on this board has just kept amazin me! I´m from Germany so some of my english might seem a bit strange to you, but I think you will be able to tolerate this!

greetz, gainerxxl
 
Re: There´s a flaw

gainerxxl said:
@punschkrapfen:

Yes, there´s definitely a major flaw in the study you presented: None of the male subjects did any weight training, they did not restrict caloric intake, they did not take a specific A2 Agonist like Yohimbine, nor did they take any fatburners. Major flaw!

@all: I´m new here, in a few upcoming post i will intrdoduce
myself, post my cycle and ask some questions, since the
knowledge on this board has just kept amazin me! I´m from Germany so some of my english might seem a bit strange to you, but I think you will be able to tolerate this!

greetz, gainerxxl

welcome bro
 
Re: There´s a flaw

gainerxxl said:
@punschkrapfen:

Yes, there´s definitely a major flaw in the study you presented: None of the male subjects did any weight training, they did not restrict caloric intake, they did not take a specific A2 Agonist like Yohimbine, nor did they take any fatburners. Major flaw!

@all: I´m new here, in a few upcoming post i will intrdoduce
myself, post my cycle and ask some questions, since the
knowledge on this board has just kept amazin me! I´m from Germany so some of my english might seem a bit strange to you, but I think you will be able to tolerate this!

greetz, gainerxxl
hast du so einen ähnlichen Nick auf dem bbszene-board? gainer war hier wohl schon vergeben, da tummeln sich doch ein paar mehr Leute als in den kleinen D-Boards :D

ok, so they didn't work out. But this also is true for this recent study:

Eur J Endocrinol 2002 Apr;146(4):505-11 Related Articles, Books, LinkOut


Testosterone substitution of hypogonadal men prevents the age-dependent increases in body mass index, body fat and leptin seen in healthy ageing men: results of a cross-sectional study.

Rolf C, von Eckardstein S, Koken U, Nieschlag E.

Institute of Reproductive Medicine of the University, Domagkstrasse 11, D-48129 Munster, Germany.

INTRODUCTION: In healthy men, body weight and total fat content increase with advancing age, while serum testosterone levels decrease. In order to elucidate whether a causal relationship between these phenomena exists, we investigated the influence of testosterone or human chorionic gonadotrophin substitution on body mass index (BMI), total fat mass and serum leptin in testosterone-treated and untreated hypogonadal patients in comparison with ageing eugonadal men. METHODS: In a cross-sectional study, the inter-relationships of body weight, total fat mass, serum sex hormones and leptin were analysed in untreated hypogonadal men (n=24; age 19-65 years), treated hypogonadal men (n=61; age 20-67 years) and healthy eugonadal men (n=60; age 24-78 years). Total fat mass was assessed by bioimpedance measurement. Univariate and multiple linear regression analysis was used to detect possible differences. RESULTS: In eugonadal men, serum testosterone levels decreased with advancing age (correlation coefficients: r=-0.71; P<0.0001), while BMI (r=0.39; P=0.002), total fat content (r=0.51; P<0.0001) and leptin (r=0.48; P<0.0001) increased significantly. In untreated hypogonadal patients, an increase in BMI (r=0.50; P=0.013) and total fat mass (r=0.41; P=0.044) was also observed with advancing age. However, in substituted hypogonadal patients, no age-dependent change in BMI (r=0.067; P=0.606), body fat content (r=-0.083; P=0.522), serum testosterone (r=-0,071; P=0.59) or serum leptin (r=-0.23; P=0.176) was found. CONCLUSION: Since testosterone-substituted older hypogonadal men show BMI and fat mass similar to those of younger eugonadal men and since non-treated hypogonadal men are similar to normal ageing men, testosterone appears to be an important factor contributing to these changes. Thus ageing men should benefit from testosterone substitution as far as body composition is concerned.

now, T levels to directly contribute to body composition, regardless if ppl work out or not, use fatburners or not or diet.

Maybe we could conclude that estrogen suppression does only work if the subjects is also on a diet (and does work out, duh ;) ) and does additional things to boost fat mobilization (CKD :confused: )
 
Have any of you had your blood tested to see if the anti-estrogen your taking are actually working?

I'm asking because I am on was on L-dex 5 drops ED and my estrogen levels were 7 times normal levels. At only 400mgs of cyp per week. I have increased the L-dex to 7 drops or 1mg ED and will have my blood rechecked on the 1st.
 
ryker, keep us posted bro as I'm very interested in your results...I'm
Test 1000 mgs a week
50-75mgs of d-bol aday
75 mgs a day of fina
l-dex@1mg a day

I have little to no bloat and gains are coming quite nicely...Usually I get moon faced off 500mgs a week of cyp...So I think the l-dex is at least doing something....
 
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