It will have SOME impact,as it has anti-estrogenic activity at the hypothalamus(which translates to increased gRH production if ANDROGEN plasma levels aren't drastically elevated).Clomid is much more powerful though,as it influences not only Hypothalamic E/R's,but Pituitary E/R's as well.Translation?Clomid stimulates catalystic(male) hormones much more fluidly than nolvadex.