Nolvadex rebound?

[xonic2xonic2]

How common is a rebound effect after stopping Nolvadex?

I am thinking that when using Nolvadex that there is still a tonne of estrogen floating around it just cannot bind to receptors well.

From what I can makeout, arimidex/AI's and proviron will actually block the the conversion of test > estrogen BUT what if you did not use these? How do you effectively dispose of the estrogen excess? Maybe taper off nolvadex?

Thanks!

 

[sigmund]

How common is a rebound effect after stopping Nolvadex?

I am thinking that when using Nolvadex that there is still a tonne of estrogen floating around it just cannot bind to receptors well.

From what I can makeout, arimidex/AI's and proviron will actually block the the conversion of test > estrogen BUT what if you did not use these? How do you effectively dispose of the estrogen excess? Maybe taper off nolvadex?

Thanks!

As I understand it the estrogen from Nolva is very mild and doesn’t produce a lot (if any) activity at the receptors. Nolva therefore prevents receptor sites from binding active more powerful estrogens.

Although Nolva increases estrogen, it’s so weak that it has very little / no effect. Once you finish taking Nolva the receptor sites gradually return to normal and are able to bind the more powerful estrogens again however by that time (in the conclusion of PCT) there should be less “harmful” estrogens circulating as testosterone has returned to normal levels - so in my opinion no need for tapering.

Hope that is of some help

Sig

 

[paul allen]

As I understand it the estrogen from Nolva is very mild and doesn’t produce a lot (if any) activity at the receptors. Nolva therefore prevents receptor sites from binding active more powerful estrogens.

Although Nolva increases estrogen, it’s so weak that it has very little / no effect. Once you finish taking Nolva the receptor sites gradually return to normal and are able to bind the more powerful estrogens again however by that time (in the conclusion of PCT) there should be less “harmful” estrogens circulating as testosterone has returned to normal levels - so in my opinion no need for tapering.

Hope that is of some help

Sig

Thats right.

I think your interpretation of how nol works is slightly off xonic, there should be no estrogen rebound caused by the nolvadex, as it has no effect on estro levels just blocks the levels which are already present, so any rebound will be due to blocking estrogen such as anti-a's.

 

[xonic2xonic2]

Thanks guys but what I mean is that there is an excess of estrogen due to coming off (+ from HCG if used.) The nolva reduces the ability of this estrogen to do do anything, but it is still there right? So once you stop the nolva is there still not an over abundance of estrogen and now it has the ability to bind! I did search and found several references to estrogen rebound after stopping nolvadex and the common "solution" was the use of proviron. This sounds reasonable as the proviron (and I guess AI's as well) will inhibit estrogen production but my question was what if it is too late? What if there was lots of estrogen produced and you are just using nolvadex to stop it from doing anything.... what happens when you stop the nolva?


Thanks again guys!

 

[ceo]

are you just using nolva for PCT or do you have existing gyno?

 

[xonic2xonic2]

This is more of a general curiosity....I am sure there are plenty of ppl who have used nolva with highly aromatizing gear and HCG, both of which cause estrogen buildup... so my question remains... if you are simply blocking the effects of the estrogen, do estrogen levels not still remain high and therefore when you stop the nolvadex cause associated problems (gyna or at least bloat, skin problems etc.?) Essentially how can/does the body get rid of the excess estrogen once it is already present (you did not do anything to stop its production or conversion from test.)

Thanks again! I am really hoping one of the docs will jump in on this...

 

[ceo]

I find a minimal dose (as little as 10mgs/day) of tamoxifen will stave off gyno, so stay on it all the way through your PCT, and possibly longer.
As for asking how the body gets rid of estrogen...how does it get rid of testosterone? Lets say you stop producing testosterone due to HTPA shutdown for ex. So by your thinking you would be wondering "well hey, Ive still got all that test in there right?" No. The body eventually cycles it out...like everything. So, if there's no more test being produced, you run out then youre on HRT. So, yes the estrogen leaves...not sure how long it takes for it to be at a minimal level as to not induce gyno, but does go.
All that said I go back to my original question:
are you just using nolva for PCT or do you have existing gyno?
and I will add, are you just CONSIDERING/or now using nolva for PCT or do you have existing gyno?

 

[The_first_athlete]

As I understand it the estrogen from Nolva is very mild and doesn’t produce a lot (if any) activity at the receptors. Nolva therefore prevents receptor sites from binding active more powerful estrogens.

Although Nolva increases estrogen, it’s so weak that it has very little / no effect. Once you finish taking Nolva the receptor sites gradually return to normal and are able to bind the more powerful estrogens again however by that time (in the conclusion of PCT) there should be less “harmful” estrogens circulating as testosterone has returned to normal levels - so in my opinion no need for tapering.

Hope that is of some help

Sig

I dont think thats what he meant.

As far as previous circulating converted estrogen from your cycle goes, I generally use nolva for an extra 30-45 days after my last shot and havent had any problems (*altho I do use clomid which also helps to rise the test?estro ratio*)

 

[xonic2xonic2]

Thanks again guys. CEO I'm not doing squat right now (except checking out some low dosage dbols.) I have a shitload of gear, nolva and hcg and am planning my biggest/best cycle to date. In the past I have been just fine on moderate dosages of various gear for up to 10 weeks with no PCT, no big crash, no gyna. I don't think I have ever exceeded my genetic potential (nor do I intend on it) and anything I lost post cycle was due to slack training/bad diet and fortunately all came back (and more) naturally. The only thing that pissed me off was post cycle acne for MANY months afterwards and I suspect this was from estrogen levels.

Like I said, I am essentially just curious about the physiology and how one can expect to to have high estrogen levels that cause problems if you have caused your body to convert/produce estrogen and only blocked it not stopped it's production.

What I am hearing back suggests that it will just come down naturally.