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no spleen oral advice

HaZaRDouZ

New member
Does not having a spleen affect the digestion of oral steroids? If so is it THAT harmful, my friend is interested in trying DBOL and has no spleen. Info is appreciated.
 
Short answer: No problems, as the spleen is a non digestive system.



FYI:
The spleen is formed by reticular and lymphatic tissue and is the largest lymph organ. The spleen lies in the left hypochondriac region of the abdominal cavity between the fundus of the stomach and the diaphragm. It is purplish in colour and varies in size in different individuals, but it is usually about 120mm (4.75 inches) long, 70mm wide (2.75 inches) and 25 mm (1 inch) thick. It weighs about 0.2 Kg (just under half a pound).

Structure: The spleen is slightly oval in shape with the hilum on the lower medial border. The anterior surface is covered with peritoneum. It is enclosed in a fibroelastic capsule that dips into the organ, forming trabeculae. The cellular material, consisting of lymphocytes and macrophages, is called splenic pulp, and it lies between the trabeculae. Red pulp is the part suffused with blood and white pulp consists of areas of lymphatic tissue where there are sleeves of lymphocytes and macrophages around blood vessels.

Blood passing through the spleen flows in sinuses which have distinct pores between the endothelial cells, allowing it to come into close association with splenic pulp. One of the main functions of the spleen is to bring blood into contact with lymphocytes. As blood flows slowly through the spleen, any disease organisms within it are likely to come into contact with lymphocytes in the spleen tissue. This contact activates the lymphocytes, which can then attack the foreign invaders. As blood passes through the spleen, macrophages remove worn-out red and white blood cells and platelets. These macrophages produce the pigment bilirubin from the breakdown of haemoglobin and release it into the blood plasma. Bilirubin is removed from the blood by the liver and kidneys and is excreted in the bile and to a lesser extent in the urine. Because a great deal of blood circulates through the spleen, this organ serves as a kind of reservoir for blood. Adrenaline and sympathetic nerve discharge stimulate the spleen to contract, releasing much of its blood into the circulation. This function is important especially during haemorrhage, but it is not considered essential in humans. (The reservoir function of the spleen is considered especially important in dogs and other carnivores.) The spleen appears to store platelets in humans, and a large percentage of the body's platelets are normally found there. Although the spleen performs many important functions it is not vital to life. Fortunately so, for of all the abdominal organs, the spleen is the one most easily and most frequently injured. A severe blow or crushing injury to the upper abdomen or lower left chest may fracture the ribs that protect the spleen and cause rupture of the spleen itself. When the spleen is ruptured, extensive, sometimes massive haemorrhage occurs. This condition is usually treated by prompt surgical removal of the spleen (splenectomy) to prevent death due to loss of blood and shock. (When surgery--either splenectomy or occasionally surgical repair--is not performed on an injured spleen, the mortality rate is about 90%.) When the spleen is surgically removed, some of its functions are taken over by the bone marrow and liver; other functions are simply absent, and the body manages without them.
 
saiyanjin said:
Does not having a spleen affect the digestion of oral steroids? If so is it THAT harmful, my friend is interested in trying DBOL and has no spleen. Info is appreciated.

I lost my spleen after being ejected during a car accident in 1999. It has had no adverse effect on any part of my life including oral AAS.
 
The lymphatic system compensates for splenic loss (its a filter basically, but blood instead of lymph).
Has no impact on drug metabolism.
He should be fine on dbol.
 
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