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Need some serious help bros! Dostinex not working!
- Thread starter Maxx Out
- Start date
columbia58
New member
Maxx Out said:
How much tren and how long...are you using anything else...I am no expert but would like to know...
monkey arms
New member
I get those sides as well, the only thing do is stop using it. They go away with in 10 days. Are you getting little painful lumps under your nips? If so, they may not be all that serious. I've lived with them for a few weeks while cycling and they have always, always gone away on their own.
Goldprospector
New member
I just finished a Tren/Test cycle and was getting the same thing in the beginning. I threw in some Nolva @ 20mg ED, along with the Dost (E4D) and A-dex (EOD). I ran the Nolva for about 2 1/2 weeks until the symptoms subsided. Then i stopped taking it. I kept the Dost and A-dex going. The symtoms returned late in the cycle but only very mild and I did not add the nolva as of yet. I am done with the tren but am finishing the cycle with Test/Winny/Var and the sysmtoms are not noticable. I will add Nolva again in PCT.
bicepts101
New member
Maxx Out said:
well the thing about dostinex/cabergoline is ur supposed to start using it a week or 2 prior to using progest derived drugs to build up a decent concentration. it takes some time to take effect.....
Bruce
New member
yeah bro been off deca 6 weeks or 7. my nips were puffy before and a little sore, i was freakin cause nolva and adex did nothing. i spoke with genetic about getting some femara or dostinex and he said that if my lumps were gone to leave it be. i did so and they are fine now. still a bit erect, but fine. i will be using femara next time in conjunture with my cycle of deca
concordsize
New member
If i were you i would stop the tren and try it at a later date.
Güclü_oglan
New member
get some nolva incase you got fake gear (gynocomastia extremely rarely occur without estrogen present)
bicepts101
New member
Maxx Out said:
im pretty sure there has to be certain amounts of estrogen, progestorone, and igf to cause gyno....i could be wrong here
bicepts101
New member
Maxx Out said:
yes im saying an over abundance of one and high amounts of the other is needed to cause gyno....like i said done quote me though i could be wrong
U
UA_Iron
Guest
dostinex does nothing for progesterone sides either...
bicepts101
New member
UA_Iron said:
wrong...dostinex does in fact lower prolactin levels
bicepts101
New member
UA_Iron said:
wrong... here:
15 patients (8 women, 7 men) were treated with Dostinex, once weekly, for 48 weeks.
Results:
A 93.6% reduction in prolactin levels, with normal levels obtained in 73% of patients
5 patients who had previously been unable to achieve normal prolactin levels on other dopamine agonists, achieved normal prolactin levels on Dostinex
gonadal function was restored in all hypogonadal men
75% of premenopausal women with amenorrhea experienced return of gonadal function
11 of 15 patients experienced tumor shrinkage
minimal side effects – no patients discontinued Dostinex because of intolerance
Colao, A. et al. 1997. Long-term and low-dose treatment with cabergoline induces macroprolactinoma shrinkage. J Clin Endocrinol Metab 82(11): 3574-3579.
23 patients with macroprolactinomas Results:
normalization of prolactin levels in 18 patients within 3-6 months at 0.5 mg/week
tumor volume reduction greater than 80% occurred in 61% of patients at the 12-24 month follow-up
the complete disappearance of the tumor occurred after 6 months in one patient and after 1 year of treatment in 5 patients
visual field defects were improved in 90% of patients who experienced them
Conclusions
In general, the data suggests that Dostinex is a better tolerated and a more effective dopamine agonist that bromocriptine in the treatment of prolactinomas. Dostinex effectively lowers prolactin levels and shrinks tumor size in a high percentage of cases, making it a good first option in the treatment of both micro- and macroprolactinomas.
Additional Resources
Ciccarelli, E., Guisti, M., Miola, C., Potenzoni, F., Sghedoni, D., Camanni, F., and G. Giordano. 1989. Effectiveness and tolerability of long term treatment with cabergoline, a new long-lasting ergoline derivative, in hyperprolactinemic patients. J Clin Endocrinol Metab 69(4): 725-728.
Cannavo, S., Curto, L., Squadrito, S., Almoto, B., Vieni, A., and F. Trimarchi. 1999. Cabergoline: a first-choice treatment in patients with previously untreated prolactin-secreting pituitary adenoma. J Endocrinol Invest 22(5): 354-359.
coloradosteve
New member
Your natural test levels could be causing the gyno? The Tren and Eq might create a synergenic effect that causes natural test to convert to estrogen at a greater rate than without Tren and Eq.
U
UA_Iron
Guest
bicepts101 said:
Prolactin and Progesterone are NOT the same thing.
who is in fact wrong?
bicepts101
New member
UA_Iron said:
ok bro technically you are 100% correct
so what are some sides that progestorone can create? prolactin, growth of breast tissue
prolactin is responsible for breast development. plus high prolactin levels induces the estrogen receptor to become more sensitive. thus making the user more prone to gyno. i believe its best to eliminate estrogen and prolactin cause, synergistically, they create havic.
**"prolactin may have a direct stimulatory effect on mammary tissue development, but only in the presence of high estrogen levels"
**Ismail AA, Barth JH.Ann Clin Biochem 2001 Nov;38(Pt 6):596-607
this is relavant because most cycle involve high aromatizing compounds. so theoretically eliminating estrogen would rid everyone of gyno....probably not the case IMO im sure levels of prolacting still will reck havic in presence of low levels of estrogen
U
UA_Iron
Guest
progesterone is a bitch - I'm not sure there's too many people that could explain the mechanism involved in which it causes gyno - I dont even know how myself. I think the same goes for prolactin...
I think the only viable progesterone options are winny (to which degree it binds to progesterone is unknown), formestane (no one uses this, or the few results arent anything spectacular) and b6 (which again is unknown).
I have seen flow charts for the way in which progesterone, prolactin and estrogen interact - and if I find them I'll post 'em.
I think the only viable progesterone options are winny (to which degree it binds to progesterone is unknown), formestane (no one uses this, or the few results arent anything spectacular) and b6 (which again is unknown).
I have seen flow charts for the way in which progesterone, prolactin and estrogen interact - and if I find them I'll post 'em.
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