NANDROLONE AND OXYMETHOLONE x GYNECOMASTIA.

[Barth]

This question is an opinion research. Which the most likely cause of the gynecomastia caused by the nandrolone and oxymetholone?
1- Prolactin (Protection: bromocriptine)
2- Progesterone (Protection: winstrol??)
3- Estrogen (Protection: tamoxifen)
I know that this question is not clarified still, but I wanted to know the opinion of all. Please, answers. I thank the answers.

 

[bbkingpin]

I always take Nolva even with a deca only cycle. Nolva binds at estro receptor in the breast tissue.

 

[SCOTTY-TWO-HOTTY]

Deca(Nandrolone)and Anadrol(Oxymetholone)are both Nor-19 Hormones... Tren is a third Nor-19 AAS, I don't know of any others. Nor-19 steroids have a strong affinity for the Progesterone receptor. If Gyno occurs when using these AAS, it is caused by Progesterone not Estrogen.

 

[biganth01]

After many cycles i feel that Deca/Tren gave me the worst problems with gyno! I recently took some Nandrolone Phenyl Prop,and my nipples got sore real fast! Took it out and the pain went away! Now i stick with Test/EQ,shame cos Tren was awsome for strength and hardness :-(

 

[The Bigfella]

Oxymetholone is 3 only and is not a progestin.

Nandrolone is 1, 2 and 3.

The best protection for progesterone is avoiding elevated estrogen, this would best achieved through dosing of an aromatase inhibitor. Winny is a weak remedy and more a nice to have IMO

Bigfella.

 

[Sigmund Roid]

Deca(Nandrolone)and Anadrol(Oxymetholone)are both Nor-19 Hormones...

This is not true, only deca is 19-nor.

Can oxy really convert to an estrogen? I thought it only converted to DHT.....

 

[The Bigfella]

This is not true, only deca is 19-nor.

Can oxy really convert to an estrogen? I thought it only converted to DHT.....

Oxymeth, does not convert to estrogen, it is itself estrogenic, it has similarities with its A-ring to those of estradiol even though it is not an aromatic A-ring does not need a conversion. Nolvadex or Clomid is the best protection as it targets the ER primarily.

BTW, it does not and cannot convert to DHT, only test does that and Oxymeth has no interaction at all with the enzyme 5-alpha reductase.

Bigfella.

 

[Sigmund Roid]

Oxymeth, does not convert to estrogen, it is itself estrogenic, it has similarities with its A-ring to those of estradiol even though it is not an aromatic A-ring does not need a conversion. Nolvadex or Clomid is the best protection as it targets the ER primarily.

BTW, it does not and cannot convert to DHT, only test does that and Oxymeth has no interaction at all with the enzyme 5-alpha reductase.

Bigfella.

You may be right, but I still don't see similarities between the A-ring of estradiol and oxy. Oxy has an oxymethylene group (HO-CH=) on position 2, which according to me does not do anything to increase the flatness of the A-ring. The oxy A-ring has IMO the same 3D structure as that of DHT.

 

[The Bigfella]

Unlike the strong progestins (deca, tren) it does not have a 'missing' carbon atom at the 19th position. Secondly we can see that it has an OH group attached to the A ring, something that is not seen on any other androgen but is seen on estrogens! So although anadrol does not contain an aromatic A ring, nor can it be aromatised, this may expalin why it would bind to the estrogen receptor.

Bigfella.

 

[SCOTTY-TWO-HOTTY]

Unlike the strong progestins (deca, tren) it does not have a 'missing' carbon atom at the 19th position. Secondly we can see that it has an OH group attached to the A ring, something that is not seen on any other androgen but is seen on estrogens! So although anadrol does not contain an aromatic A ring, nor can it be aromatised, this may expalin why it would bind to the estrogen receptor.

Bigfella.

Good explaination Bro. So, in summary... both Deca and Tren are Nor-19 and Drol is not???