I do NOT mix them, both chemicals are very fragile(unstable) and just my oppinion i think mixing them could easily breakdown or harm one or the other..make sense? its only a slin pin, just split them up....besides i take my IGF intramuscular, and my HGH sub Q....by the way, the hand pain is INCREDIBLY BAD when you mix these two, i could hardly even sleep and had to wear carpel tunnel braces at night just to ease the pain a little