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Does the anti-estrogen effects of Masteron work like that of Nolvadex?
Masterons anti-estrogen effects
- Thread starter Smokescreen
- Start date
I've heard masteron and proviron are almost identical, and yes it would help in the prevention of anti-estrogen effects.
Yes does it's anti-estrogen effects work like that of Nolvadex? Or is it via some other way?
Here i dug this up for you. Hope this answers your question!
Masteron is a derivative of DHT (as you can tell from its chemical name: 2a-methyl-dihydro-testosterone propionate), but what they fail to tell you is that DHT and its derivatives are commonly used in treatment of certain forms of breast cancer (see the etymology here: MASTectomy, gynocoMASTia, MASTeron, get it?). Masteron is not clinically used for weight gain (as is common with most steroids), so this makes it a very unique steroid from that perspective. Unfortunately, much of the information on Masteron available in medical journals doesnt focus on weight or strength gain or even fat loss, for those reasons. Most information on Masteron focuses on its use in treating certain forms of breast cancer, and it does this reasonably well.(4)(5) To give you an idea, Masteron + Tamoxifen actually fared better than Chemotherapy for immediate objective responses from patients (8).So? What does this tell us? Well, this makes it a very exciting drug for a lot of reasons. Clearly it wont aromatize at all nor will it have progesteronic sides, remember, Nolvadex (and most ancillaries) are used to reduce estrogen for breast cancer patients, so a drug used to treat breast cancer obviously wouldnt convert to estrogen...and in fact Masteron may interact with the aromatase enzymes to inhibit aromatization of other steroids into estrogen, and may additionally interact with estrogen (as a "blocker" of sorts) at the receptor site. (4)(5) This is how it helps to combat breast cancer, obviously, but this could also be part of the reason that Masteron is considered a "cutting" or "Pre-contest" drug. Masteron may actually be very useful for combating estrogenic/progesteronic side effects yes, you read that right, if you include Masteron in your cycle, you may not need other "ancillary" drugs like Arimidex or Letrozole). Hence, much like Proviron, Masteron could be used as an anti-side-effect-drug (remember, most ancillary drugs we use to combat estrogenic sides, like nolvadex, letrozole, and arimidex were originally developed to combat breast cancer...and thats exactly what Masteron was developed and used for). Along a similar line, being a DHT (DiHydroTestosterone) derivative, its got a very nice ability to add muscle hardness to an already lean physique, remember, Masteron has a deceivingly low anabolic/androgenic ratio, but since DHT is 5x as androgenic as testosterone and has a 3-4x higher affinity to receptor sites, Masteron provides a lot of "bang for the Buck" when examined on a Mg for Mg basis
All derivatives of DHT will have some anti estrogen properties. How effective they are is dependent on the steroids ability bind to the numerous receptors
Weird. Because everytime I use proviron. I tend to get a little gyno. I'm not the only one this has happened too. Others here have claimed the same thing about proviron.
And I know for a fact that proviron does NOT lower estrogen levels. I have used proviron in the past. And have gotten many, many bloodworks while on proviron and OFF proviron. And never once has it lowered my E levels.
It gives the "impression" that my E has been lowered. How? By giving me a harder and leaner physique. But bloodwork don't lie! Bloodwork has proven many times it has NOT lowered my E levels.
And I know for a fact that proviron does NOT lower estrogen levels. I have used proviron in the past. And have gotten many, many bloodworks while on proviron and OFF proviron. And never once has it lowered my E levels.
It gives the "impression" that my E has been lowered. How? By giving me a harder and leaner physique. But bloodwork don't lie! Bloodwork has proven many times it has NOT lowered my E levels.
L
lartinos
Guest
I was always under the assumption that Masteron binded to the estrogen receptor, but I would never use it as my only drug to combat estrogen.
