Any studies available on the long term use of Arimidex? I've been off cycle for 5 weeks now, finished off with clomid, nolva and arimidex. I am still taking the arimidex at .5mg EOD. Is it safe to take this indefinately? I love it. Having low estrogen simply kicks ass. Is there any potential for a rebound effect when I come of it? Can it cause the body to produce more aromatase enzyme over time?

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