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LONG Research3, IGF-1 - Receptor Grade

DBBT said:
What is this stuff exactly? I do know it differs form regular IGF1 but i don't even know what the hell that is either. Is this comparable to HGH???


HGH is the precursor to IGF-1. The liver secretes IFG-1 (and 2, but we are only worried about 1) in response to GH in the body being released by the pituitary gland. IGF is what actually causes the anabolic growth in tissues and bones. Once GH causes the IGF release, the IGF has a half life of approx 10 minutes in the body, and is very unstable during that time.

With that said, along comes Long R IGF-1 which has added amino acids in the chain that makes up the compound. These added amino's not only increase the stability of IGF-1 (although still very volatile) it also increases the half life from 10 minutes to 10-20 hours. Receptor grade is just much more pure than media grade, but you pay for that. While mosts texts I have read state that for bodybuilding media grade is more than you would ever need, most everyone here opt's for the better receptor grade to be safe.

If you google it there are alot of great studies and texts on Insulin Like Growth Factor out there. I just read a great one from a doctor that explained how IGF when penetrating a cell not only greatly increases the amino acid uptake, but also glycogen, to such a high state that the body MUST burn fat for energy cause the IGF puts up a protective fence around the muscle cells if you will, that does not allow their use for energy. This is paraphrasing but you get the idea. Dont want to keep rattling but it gets even more interesting when you look at shooting sub-q vs. IM and the benefits of each, great stuff, I just ordered a BUTT LOAD of it after all this research time, time will tell if all is true.
 
thats a good post...if i could give you some more K i would....PM me and remind me sometime if you feel the need fr some K!

PS..thanks for that..im tired of answering IGF questions..I love to help everyone but its the same IGF question over and over!.
But no you INDY..i owe you big time
 
LftHndPwrHouse said:
thats a good post...if i could give you some more K i would....PM me and remind me sometime if you feel the need fr some K!

PS..thanks for that..im tired of answering IGF questions..I love to help everyone but its the same IGF question over and over!.
But no you INDY..i owe you big time

Dont worry, I'll be collecting back when you know what get's into my hot little hands here in a couple of days :) Thanks for that PM by the way, makes sense and I'd like to use that info to research on, without spiking everyones interest here, I think you might be onto something here. Who told you about that method of mixing the gear up ?? Doctor, trainer ?? sounds like someone with background in how the muscles work.
 
Well I am a med student(ya i went back to school after getting laid off from Charles Schwab during 9/11...and a friend of mine graduated out of Drexel University in Bio Enginering and works for Hofman LaRoche...So between us we have dont some experimenting with low doses..I tested the theory on my self..

Thanks for that positive feedback..I just based it of the area and density of a muscle. Being you can fill a muscle like your delt with 2cc safely.

I want to research some more and make a post on it.
 
LftHndPwrHouse said:
Well I am a med student(ya i went back to school after getting laid off from Charles Schwab during 9/11...and a friend of mine graduated out of Drexel University in Bio Enginering and works for Hofman LaRoche...So between us we have dont some experimenting with low doses..I tested the theory on my self..

Thanks for that positive feedback..I just based it of the area and density of a muscle. Being you can fill a muscle like your delt with 2cc safely.

I want to research some more and make a post on it.

I'll be eagerly awaiting that post !! We'll be in touch, and hey, I'll be in NYC pretty soon !!
 
Nice coming to the east coast.

Oh and to make you feel even better..The place that makes your IGF is associated with John Hopkins U (that is the Med dept)

I think i am just going to chew on some deef antler felt next time i go hunting.

I have some discuraging news for the youngsters wanting to IGF.

Basically taking IGF before you have totally matured is a NO NO.
Some studies have shown that taking IGF treatment duing your developing years has a very bad impact on your own production of IGF for the REST OF YOUR LIFE! It can also cause cases of Liver and Kidney cancer. 87% of the test subjects had tumors on their Kidneys and Liver that had IGF treatment.

On a mature subject IGF has alot of benificial effects. Such as blood suger regulation, it will help strengthen your tendons and ligaments(good for people on Gear to prevent injury due to the muscle out growing the tendons max load capasity), it helps muscle cells in smooth muscles(strong organs), weight loss due to what Indy said above(it blocks cell absorbtion of glucose forcing the cell to burn its own glucose for energy), It helps protien synthesis, causing the myofibril to enlarge and promotes muscle cell splitting generating hypertrophy and hyperlasia(enlargement of muscle cells and the creation of more cells intern make more muscle fiber)

Thats a small start
 
indy69camaro said:
HGH is the precursor to IGF-1. The liver secretes IFG-1 (and 2, but we are only worried about 1) in response to GH in the body being released by the pituitary gland. IGF is what actually causes the anabolic growth in tissues and bones. Once GH causes the IGF release, the IGF has a half life of approx 10 minutes in the body, and is very unstable during that time.

With that said, along comes Long R IGF-1 which has added amino acids in the chain that makes up the compound. These added amino's not only increase the stability of IGF-1 (although still very volatile) it also increases the half life from 10 minutes to 10-20 hours. Receptor grade is just much more pure than media grade, but you pay for that. While mosts texts I have read state that for bodybuilding media grade is more than you would ever need, most everyone here opt's for the better receptor grade to be safe.

If you google it there are alot of great studies and texts on Insulin Like Growth Factor out there. I just read a great one from a doctor that explained how IGF when penetrating a cell not only greatly increases the amino acid uptake, but also glycogen, to such a high state that the body MUST burn fat for energy cause the IGF puts up a protective fence around the muscle cells if you will, that does not allow their use for energy. This is paraphrasing but you get the idea. Dont want to keep rattling but it gets even more interesting when you look at shooting sub-q vs. IM and the benefits of each, great stuff, I just ordered a BUTT LOAD of it after all this research time, time will tell if all is true.

tell me about sub q and im diff's...and K to you for all that good stuff
 
Basically GH gets injcted sub q because it is picked up your liver and the capularies in your intestines. IGF-1 is produced in those areas HGH stimulates the production and release of IGF-1. Studies showed that there is a high level of IGF in your intestines. GH gets turned in to igf via the liver. The rest of it gets put in to your blood stream via the capularies in your intestines that transports the nutrients from food.

Being you are by passing the conversion part by using IGF, IGF is the part that directly effects the muscles. You inject IM in the group that is being worked to irrigate the muscle group with the amminos and protiens from IGF. It has a much quicker and more efficient effect on the muscle.

It takes several hours for the IGF to pass from a Sub Q injection to the muscles. IGF-1 is also very unstable when it gets broke down in the body, due to this it may not be as effective by the time it reaches the muscles. Though Long R3 has an extra ammino bonded to it making it a bit more stable and with it a long shelf life(as stated by INDY) why risk it. Get the full half life right in to the muscle.

Being IGF works how i stated earlier its better to inject IM.
 
"I have some discuraging news for the youngsters wanting to IGF.

Basically taking IGF before you have totally matured is a NO NO. "

What do you believe is the minimum age for IGF-1?
 
Thats all depending on the person. The tests were conducted during developement of the internal organs. Your natural levels of IGF are the highest during puberty. I would not suggest the use untill lets say mid 20's to play it safe.. I would say when organs like the liver and kidneys are fully developed.

Ill find out more.
 
Oh ya...the reason..is because it works on the smooth muscle of organs. When the smooth muscle is growing subjecting it with extra IGF can cause abnormal growth(tumors)

Of topic..it helps out transplant patients
 
LftHndPwrHouse said:
Oh ya...the reason..is because it works on the smooth muscle of organs. When the smooth muscle is growing subjecting it with extra IGF can cause abnormal growth(tumors)

Of topic..it helps out transplant patients


Well bro I cannot answer that with the accuracy I would like to at the moment as I have 3 laptops and evidently the information I saved is not on this one. I will find it and get it to you cause I wanted to paste it into a document for my own archives. I remember that first of all it works both ways much like gh does, either way will increase IGF-1 levels in the bloodstream. Site injections IM does however favor the muscle growth and instantaneous pumps and blood flow while still allowing the body to burn fat vs. muscle for energy. Sub-q shots were much like gh in that adipose tissue is reduced in the spot, but I cannot recall how/why and wont speculate on that to save my reputation for being truthful and honest. Bottom line is both are good, IM is better for growth of that particular muscle, sub-q is better for leaning. When I get all my information together I have compiled I will make sure you get it or If I find it quickly will get it right here in the thread.
 
i agree about the sub q injections for leaning and IM for growth. Both do work!

The tumor part was from a test on developing organs.
 
v shape said:
"I have some discuraging news for the youngsters wanting to IGF.

Basically taking IGF before you have totally matured is a NO NO. "

What do you believe is the minimum age for IGF-1?


Like GH I would be safe and wait till 35 if possible, most wont, but it's best advised. although GH is much more targeted at that range for medical reasons, I think IGF being seperated and on it's own can relax that abit, but 25-28yrs would be the minimum for me to advise.
 
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