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toilet hamster
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"However, a drink providing only the BCAA leucine was able to promote full recovery of post-workout protein synthesis levels to pre-training values. In addition, by adding carbohydrate to the beverage, protein synthesis was higher after the workout than before the workout. Since this beverage increased blood insulin levels, the author of the study concluded that insulin indeed had a synergistic effect with leucine on protein synthesis.
The results of this study and others have lead researchers to believe that within the muscle cell, there's one particular regulatory pathway for protein synthesis that's stimulated by insulin, but dependent on leucine (27). If insulin is present and leucine isn't, then protein synthesis can't maximally be stimulated. If leucine is present and insulin isn't, protein synthesis can't be maximally stimulated. But give 'em both and look out!
Since leucine has this great impact on muscle protein synthesis and since levels of leucine, much like glutamine, decline during exercise, it only makes sense to supplement with leucine after workouts (28). In the end, it appears that leucine, along with protein and carbs, will lead to the greatest increases in protein synthesis. "
The results of this study and others have lead researchers to believe that within the muscle cell, there's one particular regulatory pathway for protein synthesis that's stimulated by insulin, but dependent on leucine (27). If insulin is present and leucine isn't, then protein synthesis can't maximally be stimulated. If leucine is present and insulin isn't, protein synthesis can't be maximally stimulated. But give 'em both and look out!
Since leucine has this great impact on muscle protein synthesis and since levels of leucine, much like glutamine, decline during exercise, it only makes sense to supplement with leucine after workouts (28). In the end, it appears that leucine, along with protein and carbs, will lead to the greatest increases in protein synthesis. "
