I somewhat use the EF/C&C philosophies in real life to an extent.
Everytime I pass a fat person, I refer to them as Tuc. Everytime I see a bald, bleached goatee sporting wannabe bodybuilder, I call 'em Cosmo.
Instead of giving a person karma who I find funny, I punch their arm until it turns green. If I see transvestite twins walking hand in hand, I refer to them as Fickle Zima and Decaffinated Coffeebox.
I stay away from all blondes carrying a beating fish and if I see a big breasted red head batting her eye lashes, I ask her if she likes anal then run as fast as I can before she can "eh" me to death.