Intesting OT and cancer study...

[Guvna]

Intersting OT and cancer study...

http://www.ncbi.nlm.nih.gov/entrez/...d&dopt=Abstract&list_uids=10526287&query_hl=1


Intratesticular leiomyosarcoma in a young man after high dose doping with Oral-Turinabol: a case report.

Froehner M, Fischer R, Leike S, Hakenberg OW, Noack B, Wirth MP.

Department of Urology, Universitaetsklinikum "Carl Gustav Carus," Technical University of Dresden, Dresden, Germany.

BACKGROUND: Androgenic anabolic steroids have been suspected of activity as carcinogens in the development of carcinoma and angiosarcoma of the liver and adenocarcinoma of the prostate. Although the proliferation of smooth muscle cells is stimulated by sexual steroids, to the authors' knowledge a possible relation between androgenic anabolic steroids and the development of leiomyosarcoma has not previously been reported in humans. METHODS: A 32-year-old man underwent right radical orchiectomy for a tumor of the upper pole of the right testicle. Routine histopathologic examination and immunohistochemical staining were performed. RESULTS: The tumor was identified as an intratesticular leiomyosarcoma based on its typical growth pattern and the characteristic immunohistochemical staining profile. The patient reported a 5-year history of systematic use of high dose Oral-Turinabol (4-chloro-1-dehydro-17alpha-methylteststerone) that began at age 18 years and stopped approximately 9 years before presentation. CONCLUSIONS: The rarity of intratesticular leiomyosarcoma, the experimental induction of similar tumors in animals by androgens and estrogens, and the unusually young age at presentation of the patient in the current study support the hypothesis that high dose doping with androgenic anabolic steroids could have played a cocarcinogenic role in the development of the tumor in this case. Copyright 1999 American Cancer Society.



discuss.

 

[sandman_007]

testicular cancer? this can be very deadly if not caught early. look at lance armstrong, though he did survive

 

[mendo]

I wouldn't call it conclusive...but it is an interesting read. Thanks Guvna.

 

[Guvna]

I wouldn't call it conclusive...but it is an interesting read. Thanks Guvna.

nor would I. However, I found it browsing and thought I would post it.

 

[duke of earl]

It's an interesting read, and the sort of thing most of us don't wanna see, but

5-year history of systematic use of high dose

of pretty much any meds / ''drugs'' etc. can cause trouble



also there's absolutely no evidence to link the patients AAS use & the cancer - he probably used toothpaste too - doesn't mean it caused his illness

The only AAS I'm aware of which has some reasonable evidence liking it with caner is drol - can't fin the refs tho - anyone?

 

[Guvna]

It's an interesting read, and the sort of thing most of us don't wanna see, but



of pretty much any meds / ''drugs'' etc. can cause trouble



also there's absolutely no evidence to link the patients AAS use & the cancer - he probably used toothpaste too - doesn't mean it caused his illness

The only AAS I'm aware of which has some reasonable evidence liking it with caner is drol - can't fin the refs tho - anyone?

while not conclusive, I would still bet all the money I have in the bank that, if he hadnt have used OT, it would have been years until the cancer developed, if at all.

 

[Guvna]

The only AAS I'm aware of which has some reasonable evidence liking it with caner is drol - can't fin the refs tho - anyone?

I have seen that study. The lady used drol for like 1.5 years straight or something like that. The DID conclude it was DIRECTLY from the drol, however.


Also, saying "high dose" is very vague in the above passage. I suspect that by "high dose," it was really just regualr bbing dosages.

Also, Since really anything outside of medically perscibed drugs could be said to be abused. I suspect he cycled just like the rest of us, but they count the entire time form when he started, time off, and then when he stopped permenantly.

 

[Guvna]

"Can I drink winny" gets 1000 hits, but this gets 100. Damn.

 

[sparetire]

thanks for bumming my high bro.. i am ordering tbol tomorrow! bah! the thing that sticks out in this is the "high DOSE" statement. Everything in moderation..look at all the freaks who use more than 2-3 grams per week..people wonder why they die from some kind of brain aneurism or cancer...gee.....

lol..

 

[mendo]

"Can I drink winny" gets 1000 hits, but this gets 100. Damn.

Yeah people on here don't like to read negative scientific info about gear. If you said you gained 30 lbs off it...you'd get 2000 hits, but if you dig up evidence of a potential health risk...people ignore it. Meanwhile, the mainstream media just trashes gear and won't talk about the positive aspects. I think the truth is somewhere in between... Steroids aren't the evil killers some people think, but they aren't totally harmless and healthy either.

 

[Guvna]

thanks for bumming my high bro.. i am ordering tbol tomorrow! bah! the thing that sticks out in this is the "high DOSE" statement. Everything in moderation..look at all the freaks who use more than 2-3 grams per week..people wonder why they die from some kind of brain aneurism or cancer...gee.....

lol..

True, but anything over replacement for t levels could be considered "high dose."

 

[Guvna]

Yeah people on here don't like to read negative scientific info about gear. If you said you gained 30 lbs off it...you'd get 2000 hits, but if you dig up evidence of a potential health risk...people ignore it. Meanwhile, the mainstream media just trashes gear and won't talk about the positive aspects. I think the truth is somewhere in between... Steroids aren't the evil killers some people think, but they aren't totally harmless and healthy either.

Well said bro. agree 100%

 

[dr0832]

yeah high dose from a medical stand point would be the typical bb dosage. There not talking about him taking 10g of turinabol a day, just more then a doctor would prescribe a person. And for people saying this is inconclusive, you guys need to smarten up to reality and realize that this shit we play with does have serious long term side effects. These studies and incidents where people used gear and got cancer, are not just a conincidents. I am sorry to say it because I like gear too but this shit causes bad long term side effects. And people may say well I don't abuse it, I use 2 cycles a year. But when someone does 2 cycles a year for 10+ years, if your start in your early 20's, this would definitely amount to a sufficent amount of gear use that will probably lead to bad long term sides. You guys can ridicule me and my opinion but your only fooling yourselves. And even if you take the stance that gear will only speed up the formation of pre existing cancer, realize that many many people in the US are diagnosed with cancer ever year, which means theres a good chance at least a majority of us already have some pre-existing cancer.