Serzone is a prescription anti-depressant. It's a MAO inhibitor. Its basically a generation older than the SSRI's like Prozac, Zoloft, and Paxil.
There's some speculation that taking Prozac immediately after E usage may help alleviate the crash in seritonin levels that takes place over the following days. There's also SOME speculation that this may prevent SOME of the neural damage associated with E. I haven't read this regarding Serzone, though. Keep in mind, all side effects of taking E can be avoided by not taking E....
St J's MAY be a SSRI, it's tough to find any (validated) information that conclusively shows how it does what it does. Or, for that matter, if it really does anything. Anyhow, 5-HTP does seem to do something and it should NOT be taken with SSRI's.