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I'm high on SAM-e!

Adverse effects

Gastrointestinal disorder, diarrhea, dyspepsia, anxiety, headache, psychiatric, insomnia, allergy and rashes.[14] Long term effects are unknown.

[edit] Serotonin syndrome

There is concern and one report of the potentially fatal serotonin syndrome in association of SAMe with other medications.[22][23]

[edit] Induction of mania

"In an extensive MEDLINE search on SAMe, Kagan found induction of mania in one patient out of fifteen treated with parenteral SAMe. In the same review Lipinski found the apparent induction of mania in two patients with bipolar disorder (total of nine depressed patients studied).[24] Both depesssion and mania can be life-threatening conditions that may cause cognitive dysfunction even after remission.[25] There is concern that antidepressants in general can induce hypomania and/or mania.[26]"

Yikes
 
You know ive actually looked into getting some. do you take it for the joint benefits or for the mood benefits? its been prescribed in europe for a while, but u can get it OTC here. People claim it's like a SSRI without the side-effects, good for curing anxiety and shit. hows it workin for u
 
CrazyRussian said:
You know ive actually looked into getting some. do you take it for the joint benefits or for the mood benefits? its been prescribed in europe for a while, but u can get it OTC here. People claim it's like a SSRI without the side-effects, good for curing anxiety and shit. hows it workin for u


Its really hard to tell at this point; but I am hoping to get all of the benefits - joint and elevate my mood!

I'll let you know but I hear good things.
 
weird..this is an all natural remedy for lupus. My rheum told me about it.

How long have you been taking this?
 
Last edited:
mightymouse69 said:
Day 3 - I started at 400mg/day

Here are the results of a meta-analysis from an US Dept. of Health, thus they are not trying to sell it...However they are very conservative in their interpretation.

http://www.ahrq.gov/clinic/epcsums/samesum.htm


printed that out...will be my lunch reading material.
Interesting...I think I made a thread about this once?! Not sure.
I was going to try it for joint pain, but am waiting to see the homeopath before I put more into my body

Thanks hun
 
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