I would love to see an article or published study showing how ibuprofen really hurts gains. Ibuprofen is not liver toxic, neither is aspirin, although aspirin would be the better choice. Acetaminophen (tylenol) is the liver "killer". This post is about ibuprofen and the liver. It is NOT toxic to the liver, specially if guys just take it once in a while for a headache. Polfajefa says it's worst for your liver than alcohol. That couldnt't be further from the truth. Alcohol IS toxic to the liver, MORE SO than a little ibuprofen pill that you take for a headache. If you meant Tylenol, well, that's a different story....which by the way, it still wouldn't kill you if your were on dbol and you had a headache and you had to take tylenol. Come on guys, let's not blow this shit out of proportion. Moderation is key with everything. Use these pain meds SPARINGLY and it won't do shit to your liver, and it won't hinder your gains. If your worried about an advil/tylenol/aspirin hurting your gains, then you have other issues going on. Sorry 'bout the rant......rough day today.