You can even run this by your doctor. I have a good relationship with mine and have discussed t3 with him. 1 pill a day should have minimal benefits. Of course, it will not cause any real disturbances to your body either, so it wont hurt you to try. I'd reccommend pyramiding. Something like 1,2,2,2,2,3,3,2,2,1 could work. I think that whter youre doing 1 or a few at a time, your bodys metabolism wil speed up, causing you to sweat more, and in turn, burn calories faster. How much depends on how much you take.