No weight loss on Synthroid (100 mcg) and Cytomel (5mcg) but have had great results with Ideal Protein. Did it for almost 2.5 months Feb 2012. Went from 190 to 161lb. Am 5'10. Lost almost 30 lbs gained from Hypothyroidism/Hashimoto's. Back on to lose the last 10 lbs. From having an almost perfect physique up until 37 and overnight starting to gain weight with no explanation was horrible. Even eating super clean and exercising hard wasn't having an effect. It's a disease that takes away your beauty (hair, skin, weight). I read some people take thyroid medication to lose weight, especially Cytomel but I would be worried that it might trigger something with your thyroid. The levels used at the height of a cycle really shocked me, it's powerful stuff. I would like to know what some of the side effects some people with normal thyroid on a cycle feel? Only curious. Trust me, this condition is no fun. I would give anything to be normal again.