How important is Estrogen for man?

[Counterstrike]

If we eliminate E by using L-dex on a non cycle how different would our bodies act? is Estrogen important of man to get by do we need it or not? curious

 

[muslix]

ya i was wondering the same thing! bump

 

[SOLID]

and to those that answer please explain it in "dummy terms" so I can understand it.

 

[StRoNg_WoN]

Well we have it... but remember, taking away estrogen doesn't necessarily make our test higher... and that is what counts in my book... so I would worry about how to get your test levels higher, and how to stay in the positive nitrogen balance, rather then how to get rid of the estrogen that you may have...

Just my 2 cents...

 

[Counterstrike]

Well we have it... but remember, taking away estrogen doesn't necessarily make our test higher... and that is what counts in my book... so I would worry about how to get your test levels higher, and how to stay in the positive nitrogen balance, rather then how to get rid of the estrogen that you may have...

Just my 2 cents...

The question wasn't abotu makign my test higher read the wquestion your answer has nothign to do with my question.
I know some peopel experienced BF reduction using L-dex IF i want to spike my test levels then i'll use test. Basically is Estrogen important for our funtction as man? if not then i'm going to use L-dex and Clen for some BF reduction

 

[adoniscomplex]

Bump for a good question

 

[Bulldog_10]

haha...i was at my doctors office a while back and I asked to get my blood work done...and she asked me what I wanted to get checked. So I said liver enzymes, cholesterol, and test/estrogen levels. So the dumb bitch says "why in the world would you want to get your estrogen levels checked?!?! Estrogen is only in women."

And she went to med school supposedly...

 

[SAF]

One of the most important tasks that estrogen carries out is cholesterol regulation. I'm not a doctor, but logic would tell you that individuals with high blood and/or high cholesterol should be careful using Arimidex. This is from Anabolics 2000...

While it (Arimidex) will effectively reduce estrogenic side effects, it will also block the beneficial properties of estrogen from becoming apparent (namely its effect on cholesterol values).

If you're concerned about using Arimidex, then you may want to use Nolvadex as an alternative. This is from Anabolics 2000 as well...

Since the estrogen receptor antagonist Nolvadex is shown not to display an antiestrogenic effect on cholesterol values, it is certainly the preferred form of estrogen maintainance for those concerned with cardiovascular health.

Hope it helps!

SAF

 

[Silent Method]

I did a little bit of searching on this topic. Without going to deep, I have concluded that the concern with estrogen inhibition in men can be roughly condensed into 3 areas.

1. Negative effect regarding cholesterol regulation. (Lots of info on this site to help with that.)

2. Negative effect regarding bone resorption (especially in older men, also in men with chronic or estrogen deficiency or mutated estrogen metabolism) - NOT thought to be a problem in short term cases of decreased estrogen in men. Estrogen plays is a key to "preventing the increase in bone resorption." (Bone resorption is bone breaking down and re-form- as you get older you begin to lose the ability to re-form bone.)

3. Various nervous and related psychological functions controlled by estrogen. "In addition to its primary role as a sex hormone in women, estrogen has been shown to play a part in everything from memory to increasing the rate at which nerve cells grow. It affects the sensing of pain, has an effect on mood and is involved in regulating the brain's use of sugar." Do some homework and you will find that much schizophrenia and Alzheimer’s research is focusing on the role of estrogen metabolism.


An interesting article...

Researchers discover abnormal bone lengthening, bone mass in males with estrogen-related deficiency
Contact: Ann Harrell
(214) 648-3404
e-mail: [email protected]

DALLAS -- January 12, 1996 -- The next time you're at a professional basketball game, take a closer look at the almost 8-footer charging the basket. He may not be as strong as you think -- he may not have enough estrogen, said Dr. Evan Simpson, a biochemist at UT Southwestern Medical Center at Dallas.

Simpson is one of the authors of the first patient study linking abnormalities in male bone growth and mineralization to lack of the female hormone estrogen. "Aromatase Deficiency in Male and Female Siblings Caused by a Novel Mutation and the Physiological Role of Estrogens" appeared in the December 1995 issue of the Journal of Clinical Endocrinology and Metabolism. Researchers from the Columbia University College of Physicians and Surgeons and the University of California, San Francisco, School of Medicine, also participated in the research.

While there have been previous reports of the effect of aromatase deficiency on females, including recent work by Simpson, this article reported on the first deficiency in a male and its implications for growth and development. Simpson is a professor of biochemistry and obstetrics and gynecology at UT Southwestern and a researcher in the Cecil H. and Ida Green Center for Reproductive Biology Sciences.

Simpson and his colleagues explained how a mutation in the CYP19 gene results in a major malfunction of estrogen metabolism. The normal gene encodes an enzyme called aromatase, which converts the male hormone androgen into estrogen in gonads, bones and other body areas. Simpson, who originally cloned and characterized the gene with his associates at UT Southwestern, explained that lack of aromatase causes uncontrolled bone lengthening and a lack of bone mineralization, which results in weak bones. He said the effect of the deficiency on male development was unknown until now.

In women, this deficiency leads to female gender-related problems, failure to go through puberty, lack of breast development, failure to menstruate and cystic ovaries. Most of these conditions, however, can be treated with estrogen. If left untreated, females also may experience uncontrolled bone lengthening.

Dr. Akira Morishima of Columbia University, one of the paper's authors, first diagnosed the female patient in the journal article as having gender problems when she was 22 months old. Eventually she was recognized as the first recorded case of aromatase deficiency, a project in which Simpson also was involved. Morishima has treated the patient throughout her formative years and continues to be her physician.

The researchers later determined that her brother also carried the defective gene that causes the production of estrogen to go awry. At the time he was first examined, the boy was 14 years old and was of normal stature; however, 10 years later he was 6 feet 8 inches tall and was still growing. "Moreover, his bones were markedly undermineralized," Simpson said.

"The report of the male sibling without a functional aromatase enzyme shows that estrogen has a role in bone formation in males as well as females," Simpson said. "In the past we had assumed that androgens played the same role in the development of male bones as estrogen does in women. Clearly this is not the case."

Researchers have uncovered no problems associated with the male patient's gender development, with the possible exception of a low libido.

Another important point to emerge from this work is the fact that two siblings with aromatase deficiency have reached adulthood and are otherwise normal. This indicates that estrogen may not have an essential role in human embryonic development as was previously thought, Simpson said. Meanwhile his lab continues this research with familial DNA studies related to aromatase deficiency in both men and women.

Other participants in the study were UT Southwestern obstetrics and gynecology researchers Dr. Ke-nan Qin, a research fellow, and Carolyn Fisher, a senior research associate; and UCSF researcher Dr. Melvin Grumbach.

The work was funded in part by the March of Dimes and the U.S. Public Health Service.

 

[ZKaudio]

w/o estrogen I would eat people =-/

 

[Mike P.T.]

All of that plus building less muscle overall as estrogen plays a crucial role in glucose metabolism as well as igf-1 production and increased igf-1 sensitivity in tissues.

 

[caiza]

so less estrogen less size guys...

 

[ryker77]

l-dex does not rid your body of estrogen. It only helps to stop the conversion of androgen into estradiol. Estradiol would then bind to the estrogen receptor and increase the level of estorgen.

I'll say it again L-dex does NOT rid your body of estrogen. Do a search with my user name and you'll find the blood work to back this up.

 

[HUCKLEBERRY FINNaplex]

Ryker hit the nail on the head.It will not ELIMINATE E,it will only SUPPRESS T conversion to E by blocking of aromitase.SOME E is necessary,and even HEALTHY,it's the overload/spillover we're looking to negate as that is what's responsible for cosmetic abnormalities,and arimidex/liquidex takes care of that just fine in most users.You DO NOT want to eliminate all E from the system,that would be disastrous.Suppression should be the goal.

 

[SOLID]

so HUCK, would you say that it's bad to stack Nolva/Liquidex together while not on any gear- just doing it as an experiment to see if it help with estrogenic type fat loss. Thanks

 

[Silent Method]

l-dex does not rid your body of estrogen. It only helps to stop the conversion of androgen into estradiol. Estradiol would then bind to the estrogen receptor and increase the level of estorgen.

I'll say it again L-dex does NOT rid your body of estrogen. Do a search with my user name and you'll find the blood work to back this up.

Great point, I missed the incorrect reference "eliminating estrogen with liquidex" in the first post.

The 3 points in my post above are in reference to studies on aromatase inhibition in men.

 

[HUCKLEBERRY FINNaplex]

so HUCK, would you say that it's bad to stack Nolva/Liquidex together while not on any gear- just doing it as an experiment to see if it help with estrogenic type fat loss. Thanks

Not at all.Remember,tamoxiphen does not LOWER E production,it only prevents it from binding to and activating sites.I think that nolvadex and liquidex/arimidex is a fantastic combination.

 

[SOLID]

thanks HUCK, just what I wanted to hear.

 

[Lumberg]

I remember when I went on .5mg Arimidex/day I felt like crap, kinda sick after a few days. I probably shut down E conversion TOO much.

What nobody mentioned however is that estrogen level is one of the feedback mechanisms for test production. Thus reducing E will ramp up test production, in the absence of AS of course. This would explain why I felt stronger (and hornier) while on Arimidex alone.

JC

 

[Mike P.T.]

Ryker hit the nail on the head.It will not ELIMINATE E,it will only SUPPRESS T conversion to E by blocking of aromitase.SOME E is necessary,and even HEALTHY,it's the overload/spillover we're looking to negate as that is what's responsible for cosmetic abnormalities,and arimidex/liquidex takes care of that just fine in most users.You DO NOT want to eliminate all E from the system,that would be disastrous.Suppression should be the goal.

Yuppers!!!

Hmmm now I wonder if there are actually people who have tried using extra amounts of arimidex thinking that if a little is good then alot more would be better. Im talking like 5mg a day. Come on guys fess up. Who has tried this and was on less than 5 grams of test a week? Hehehehe.