Ya always want to take the lowest dose possible, when it comes to inhibitors. No estrogen is very bad for cholesterol, and the arteries, and estrogen is anabolic as well. I'd start 1 week in at .125ml ed or eod, and watch bp and bloat--adjust as necessary. A little extra water can be good for growth too. Too much, and you have moon face, mood swings, and extra fat gain. Watch for the signs, know your body.