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lanky
Well-known member
The metabolism of dromostanolone (2á-methyl-5á - androstan-17â-ol-3-one) was studied in three adult volunteers after oral dose of 20 mg. Solvent extracts of urine obtained after enzyme hydrolysis were derivatized with MSTFA/TMCS and MSTFA/TMIS. The structures of intact drug and its metabolites were determined by gas chromatography/mass spectrometry (GC/MS) in electron impact (EI) mode. The major metabolite (2á-methyl-5á- androstan-3á-ol-17-one), its 3â -epimer, parent compound, and several hydroxylated metabolites including intact drug were detected by comparing total ion chromatograms of control urine with that of the administered sample. Two epimers of 2á -methyl-5á- androstan-3,17â-diol were detected using selected ion monitoring. The maximum excretion of dromostanolone and 2á-methyl-5á- androstan-3á-ol-17-one was reached in 6.2-15 hr. The half-life of intact dromostanolone was 5.3 hr. About 3.0% of the administered amount was found to be excreted within 95 hr as unchanged form.
base your own conclusions about what the half life would be on a 17 alpha methyl version of this molecule(aka-superdrol). probably greater than 5.3 hours.
base your own conclusions about what the half life would be on a 17 alpha methyl version of this molecule(aka-superdrol). probably greater than 5.3 hours.
