Effectiveness of Receptor Sites

[needsize]

I read somewhere recently that the effectiveness of a receptor site to AS is directly related to the amount of the mineral, zinc, in the receptor itself. Apparently, use of AS uses up zinc stores at a high rate, and that has a lot to do with how AS quickly becomes less effective over the length of a cycle. The problem is, I can't remember where the hell I read this info, has anyone else seen anything along these lines? That would be pretty sweet if we could prolong the length of cycles by supplementing zinc.....I just bought some, $5 for a month's supply!

 

[Scotsman]

Thinkmuscle.com had an article on receptor site downregulation. The article is titled "androgen receptors down-regulate don't they" The article explores what goes on in the receptor cells and how the react to androgen antagonism.

 

[needsize]

Thanks, I went and checked out that article. To be honest though, it was only part 1 of the entire article and it didn't really give a clear picture, at least not that I was able to distinguish, as to whether or not the receptors do actually down-regulate, or why AS becomes less effective over a certain period of time on. I'm grasping at this zinc thing as it seems a really easy way to maintain effectiveness of AS, of course, you know how effective "the easy way" generally is

 

[Scotsman]

The second part of the article should be on there too. I get the newsletter on e-mail and I remember reading the second part of the study. Try a search for it and see what comes up on their site.

 

[serge]

the article you are refering to can be found on mesomorphosis.com and on anabolicextreme.com

 

[serge]

BTW, receptors do not down regulate, one theory is that when anabolic hormons are increased, your body compensates for them by creating more cortisol receptor cites, so after a while you are loosing muscle as fast as you are gaining it so net gains equal to zero.