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Frackal
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Just a question of interest I'm asking Huck, Fonz, ulter and the other ox fans/gurus:
Well, we all know that oxandrolone increases creatine synthesis and large doses of creatine work systergenically with ox because (as I understand it) oxandrolone allows you to utilize all of that extra creatine through increased synthesis.
Well according to the article originally posted by huck below, it also halts the exit of amino acids from the muscle, so if you were to take large amounts of glutamine, would you recieve a systergenic effect being the glutamine pool would continue to build up to supraphysiological levels causing I assume a very positive effect on protein synthesis/anabolism?
Hope this makes sense....
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Hey fellas,after yesterdays interest,I thought I'd pass along some more interesting info on this nifty little multi-purpose compound.The following is an excerpt taken from a column titled"Bodybuilding Pharmacology"in the May 2000 edition of Ironman magazine,ENJOY.ORAL STEROIDS:EFFECTS ON PROTEIN METABOLISM-While testosterone injections remain the cornerstone of androgen medical therapy,recent studies have focused on the effects of oral anabolics.A popular anabolic in that category is oxandrolone,formerly sold under the trade name Anavar but currently available as Oxandrin.A group of scientists recently gave injections of testosterone enanthate to healthy young men and found that the drug increased net protein synthesis(duh)and reuse of amino acids in muscle.The researchers decided to see if oxandrolone offered similar effects as an oral drug.They gave 15mgs of the drug for five days to healthy young men.They tested muscle protein synthesis and breakdown rates using sophisticated testing procedures and found that muscle protein synthesis rates increased by 44 percent after the subjects used oxandrolone,with zero affect on muscle protein breakdown.In other words,they found an anabolic effect(duh)Muscle protein synthesis increased while muscle protein breakdown didn't.The researchers also found an increase in muscle cell androgenic receptors promoted by oxandrolone.In edition,comparing the effects of testosterone in their previous study with oxandrolone in the newer study showed that oxandrolone exerts a greater anabolic effect on skeletal muscle than testosterone injections.(I'm assuming they're talking about a mg to mg basis here)Another signifigant finding was that oxandrolone prevented the exit of amino acids from muscle cells that normally occurs after an overnight fast.That would be a potent anti-catabolic effect of the drug:helping to maintain muscle cell content of amino acids.When amino acids leave the muscle,catabolic effects dominate.Using oxandrolone led led to a 65 percent increased rate of protein synthesis under fasting conditions.....Gentlemen/ladies,if you can get your hands on this marvelous compound,it should be a regular part of your stacking array,especially when inducing lypolisis for pre-contest preperations.Hope you guys enjoy this interesting little tidbit as much as I did.
Well, we all know that oxandrolone increases creatine synthesis and large doses of creatine work systergenically with ox because (as I understand it) oxandrolone allows you to utilize all of that extra creatine through increased synthesis.
Well according to the article originally posted by huck below, it also halts the exit of amino acids from the muscle, so if you were to take large amounts of glutamine, would you recieve a systergenic effect being the glutamine pool would continue to build up to supraphysiological levels causing I assume a very positive effect on protein synthesis/anabolism?
Hope this makes sense....
---
Hey fellas,after yesterdays interest,I thought I'd pass along some more interesting info on this nifty little multi-purpose compound.The following is an excerpt taken from a column titled"Bodybuilding Pharmacology"in the May 2000 edition of Ironman magazine,ENJOY.ORAL STEROIDS:EFFECTS ON PROTEIN METABOLISM-While testosterone injections remain the cornerstone of androgen medical therapy,recent studies have focused on the effects of oral anabolics.A popular anabolic in that category is oxandrolone,formerly sold under the trade name Anavar but currently available as Oxandrin.A group of scientists recently gave injections of testosterone enanthate to healthy young men and found that the drug increased net protein synthesis(duh)and reuse of amino acids in muscle.The researchers decided to see if oxandrolone offered similar effects as an oral drug.They gave 15mgs of the drug for five days to healthy young men.They tested muscle protein synthesis and breakdown rates using sophisticated testing procedures and found that muscle protein synthesis rates increased by 44 percent after the subjects used oxandrolone,with zero affect on muscle protein breakdown.In other words,they found an anabolic effect(duh)Muscle protein synthesis increased while muscle protein breakdown didn't.The researchers also found an increase in muscle cell androgenic receptors promoted by oxandrolone.In edition,comparing the effects of testosterone in their previous study with oxandrolone in the newer study showed that oxandrolone exerts a greater anabolic effect on skeletal muscle than testosterone injections.(I'm assuming they're talking about a mg to mg basis here)Another signifigant finding was that oxandrolone prevented the exit of amino acids from muscle cells that normally occurs after an overnight fast.That would be a potent anti-catabolic effect of the drug:helping to maintain muscle cell content of amino acids.When amino acids leave the muscle,catabolic effects dominate.Using oxandrolone led led to a 65 percent increased rate of protein synthesis under fasting conditions.....Gentlemen/ladies,if you can get your hands on this marvelous compound,it should be a regular part of your stacking array,especially when inducing lypolisis for pre-contest preperations.Hope you guys enjoy this interesting little tidbit as much as I did.
