care of google:
Clonazepam's pharmacological profile is similar to other anxiolytic/sedative benzodiazepines. Its basic anticonvulsive properties are also similar to those of other diazepines. Clonazepam is capable of suppressing the spike and wave discharge in absence seizures (petit mal) and decreasing the frequency, amplitude, duration and spread of discharge in minor motor seizures.
Clonazepam is well absorbed orally with maximum blood concentrations occurring in 1 to 2 hours. Clonazepam is metabolized by the liver to inactive metabolites, which are excreted mainly in the urine. Less than 0.5% of a dose is excreted in the urine unchanged and from 9 to 27% of a dose may be excreted in the feces. The half-life of the parent compound varies from approximately 18 to 50 hours
Alone or as an adjunct in the management of myoclonic and akinetic seizures and petit mal variant (Lennox-Gastaut syndrome). May also be of some value in patients with absence spells (petit mal) who have failed to respond to succinimides.
Up to nearly 33% of the patients in some studies have shown a loss of anticonvulsant activity, often within the first 3 months of clonazepam administration. In some cases, dosage adjustment may re-establish efficacy.