DNP......"LIVER DAMAGE"

[OXANDRIN]

The overproduction of lactic acid is evidence that fermentation is occuring on a large scale. Knowing that the drug can interfere with DNA replication, it makes sense to conclude that it has interefered with mitochondrial DNA and affected normal ATP production. If the mitochondria's ability to produce ATP were disrupted, the ATP would have to be produced outside the mitochondria, by fermentation taking place in the cytosol. Though it is normal for the body to use fermentation, especially by muscle cells during hard excercise, fermentation is a temporary response that cannot be sustained in humans. In the case of patients in this clinical trial, ongoing exposure to the drug would disrupt mitochondrial DNA as use continued, rendering more mitochondria unable to produce ATP. Lactic acid production as a by-product of fermentation would continue, and eventually overwhelm the liver.

 

[Fonz]

The overproduction of lactic acid is evidence that fermentation is occuring on a large scale. Knowing that the drug can interfere with DNA replication, it makes sense to conclude that it has interefered with mitochondrial DNA and affected normal ATP production. If the mitochondria's ability to produce ATP were disrupted, the ATP would have to be produced outside the mitochondria, by fermentation taking place in the cytosol. Though it is normal for the body to use fermentation, especially by muscle cells during hard excercise, fermentation is a temporary response that cannot be sustained in humans. In the case of patients in this clinical trial, ongoing exposure to the drug would disrupt mitochondrial DNA as use continued, rendering more mitochondria unable to produce ATP. Lactic acid production as a by-product of fermentation would continue, and eventually overwhelm the liver.

You do realize that the amount of lactic acid that would have to be generated outside the mitochondria would have to be so enormous as to reduce the solubility of Lactic Acid by quite a few powers of ten in order for the liver not to be able to process the Lactic Acid. Just not possible under almost any conditions. Might happen if you took say like 3000mg/day for like 10 years.....but that seems highly unlikely.

And besides, lactic acid acid is a soluble acid. You could neutralize it somewhat with a soluble base. A buffer of sorts...like Potassium Citrate or baking soda. for a length of time.

 

[bigp3]

I dont know why anyone would fuck with DNP it is bug poison for gods sake,,, you can get ripped easily enough without it

 

[needsize]

it does say "eventually", and no one stays on dnp long enough for eventually to be a problem, no one sane anyway

 

[dzulboy]

You do realize that the amount of lactic acid that would have to be generated outside the mitochondria would have to be so enormous as to reduce the solubility of Lactic Acid by quite a few powers of ten in order for the liver not to be able to process the Lactic Acid. Just not possible under almost any conditions. Might happen if you took say like 3000mg/day for like 10 years.....but that seems highly unlikely.

And besides, lactic acid acid is a soluble acid. You could neutralize it somewhat with a soluble base. A buffer of sorts...like Potassium Citrate or baking soda. for a length of time.

fUNNY I READ A BOOK THAT SAID 18 DAYS

 

[solidspine]

It is not going to happen in a 10 or 14 day cycle.

 

[Fonz]

fUNNY I READ A BOOK THAT SAID 18 DAYS

Please link me to that book. I would love to read THAT.

 

[dzulboy]

Chemical muscle enhancement said not exceed 18 days hey the dudes beeen pretty freakin knowledgeable thus far

 

[Fonz]

Chemical muscle enhancement said not exceed 18 days hey the dudes beeen pretty freakin knowledgeable thus far

You call that a REFERENCE book?

In the 1930's when DNP was legal for sale as a weight loss aid, people used it for up to 6 months, sometimes longer, with no deletirious effects.

So tell whomever wrote THAT book, to get his facts straight first through better research, before spouting rubbish.

 

[dzulboy]

well excuse me
now i know why you get ripped on
step on stage with me sometime bud we will seperate the men from the girls real fast

i've read your posts and some seem very intelligent when you can actually see what you have wrote through your ego

 

[Triple-G]

I dont know why anyone would fuck with DNP it is bug poison for gods sake,,, you can get ripped easily enough without it

Nitroglycerine is an explosive that has been used in blasting rock and in mining, but it also causes the arteries in the body (including the coronary arteries) to widen and is therefore used to treat heart attacks in humans. All a matter of the correct dosage. DNP in the range of 200-400mg a day works wonders for cutting.

 

[GoldenDelicious]

right, someone explain this "fermentation" business to me. i have never seen that nomenclature in any literature used in pharmacy.

its a huge simplification to say that dnp use would be deleterious because of mitochondrial inhibition. so huge im not really going to get too far into it except to say taht there are many many mitochondria in every cell, and ATP production is not inhibited, only retarded periodically. furthermore there is no reference to dose.

then of course you have the thousands of people using hte drug in the 30s and 80s with no reported long term sides.

im not a huge fan of dnp but the statement, and the source of the info in the first place, is a bit off

cheers

 

[MrMakaveli]

haha, I dont mean to start shit but did GD and Fonz just agree? *Feels the ground* and hell hasnt frozen over?

 

[Fonz]

well excuse me
now i know why you get ripped on
step on stage with me sometime bud we will seperate the men from the girls real fast

i've read your posts and some seem very intelligent when you can actually see what you have wrote through your ego

Yeah....Ok.

Your author is just dead wrong.

Get over it.

 

[benevolent anarchist]

You shouldn’t take it that way. You just relayed a message that you read. And Fonz made a pretty good case in direct opposition to that message. Better to ask the author to come over and explain himself than to start the “calling out” nonsense. OR Can you post the exact paragraph where the “18 days” was mentioned? Maybe that’s just the author’s personal recommendation rather than when he believes liver damage begins.

 

[needsize]

I cant imagine running dnp even for 8 days, I am currently on day 6 of 400mg(200 in the morning and 200 before bed), and the heat sucks ass. On the bright side, I am well under 10% and still losing a pound a day, along with my diet

 

[John C Calhoun]

For everything you wanted to know about DNP check out :

http://www.atsdr.cdc.gov/toxprofiles/tp64.html

Download chapter 2 health effects.

 

[The_Eviscerator]

Yeah....Ok.

Your author is just dead wrong.

Get over it.

What Author Rea was referring to was sane usage to insure safety. I am sure one could use it longer, but it would not be wise.

I think CME and BTPB are very good books. Some "internet gurus" have poo pooed them, but in 8 months of using his concepts I weigh 235 at 9-10% BF. Up from 218. Blood work has come back PERFECT. No post cycle crashes anymore and constant healthy growth.

 

[supreme]

I just started an 18 day (length of cycle was just a coincidence - had 18 caps left) of DNP at 200 mg / day.

Have done 3 previous cycles ramping up the dosage and it totally sucked!!!! -night sweats, insomnia , lethargy, dry mouth, sore throat & worst couldn't train seriously. So far 200mg and no sides except a little extra warmth and bodyfat loss. I think low dose is the way to go if you want to be able to train and function normally.

S

 

[GoldenDelicious]

haha, I dont mean to start shit but did GD and Fonz just agree? *Feels the ground* and hell hasnt frozen over?

agreeance and independent concordance are different