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Does anyone have any following information about glucosol (corosolic acid)? I'm curious in knowing more about its affects on blood glucose. It is referenced in "breaking the metabolic code" (but no references given) and I found this pubmed study, but I don't have access to anything other than the abstract.
everything else I find on it is from supp company marketing lit.
Thanks, the pubmed study abstract is listed below.
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Antidiabetic activity of a standardized extract (Glucosol™) from Lagerstroemia speciosa leaves in Type II diabetics
A dose-dependence study
William V. Judya, Siva P. Harib, W. W. Stogsdilla, Janet S. Judya, Yousry M. A. NaguibCorresponding Author Contact Information, E-mail The Corresponding Author, b and Richard Passwaterb
a SIBR, Inc., 4112 20th Street West, Bradenton, FL 34205, USA
b Soft Gel Technologies, Inc., 6982 Bandini Boulevard, Los Angeles, CA 90040, USA
Received 1 February 2002; revised 1 March 2003; accepted 29 March 2003. ; Available online 17 May 2003.
Abstract
The antidiabetic activity of an extract from the leaves of Lagerstroemia speciosa standardized to 1% corosolic acid (Glucosol™) has been demonstrated in a randomized clinical trial involving Type II diabetics (non-insulin-dependent diabetes mellitus, NIDDM). Subjects received a daily oral dose of Glucosol™ and blood glucose levels were measured. Glucosol™ at daily dosages of 32 and 48 mg for 2 weeks showed a significant reduction in the blood glucose levels. Glucosol™ in a soft gel capsule formulation showed a 30% decrease in blood glucose levels compared to a 20% drop seen with dry-powder filled hard gelatin capsule formulation (P<0.001), suggesting that the soft gel formulation has a better bioavailability than a dry-powder formulation.
Author Keywords: Type II diabetes; Blood glucose; Lagerstroemia speciosa; Glucosol™
everything else I find on it is from supp company marketing lit.
Thanks, the pubmed study abstract is listed below.
----
Antidiabetic activity of a standardized extract (Glucosol™) from Lagerstroemia speciosa leaves in Type II diabetics
A dose-dependence study
William V. Judya, Siva P. Harib, W. W. Stogsdilla, Janet S. Judya, Yousry M. A. NaguibCorresponding Author Contact Information, E-mail The Corresponding Author, b and Richard Passwaterb
a SIBR, Inc., 4112 20th Street West, Bradenton, FL 34205, USA
b Soft Gel Technologies, Inc., 6982 Bandini Boulevard, Los Angeles, CA 90040, USA
Received 1 February 2002; revised 1 March 2003; accepted 29 March 2003. ; Available online 17 May 2003.
Abstract
The antidiabetic activity of an extract from the leaves of Lagerstroemia speciosa standardized to 1% corosolic acid (Glucosol™) has been demonstrated in a randomized clinical trial involving Type II diabetics (non-insulin-dependent diabetes mellitus, NIDDM). Subjects received a daily oral dose of Glucosol™ and blood glucose levels were measured. Glucosol™ at daily dosages of 32 and 48 mg for 2 weeks showed a significant reduction in the blood glucose levels. Glucosol™ in a soft gel capsule formulation showed a 30% decrease in blood glucose levels compared to a 20% drop seen with dry-powder filled hard gelatin capsule formulation (P<0.001), suggesting that the soft gel formulation has a better bioavailability than a dry-powder formulation.
Author Keywords: Type II diabetes; Blood glucose; Lagerstroemia speciosa; Glucosol™
