A normal routine is 300mg day 1 100mg 2-10 then 50mg day 11-21. I am just fininshing up clomid myself. I didn't split them up at all and really haven't had bad sides except some extra acne.
i would say split them up, since there really isnt any reason not to. spliting them up might make your body adsorb them better. just a thought because it is easy to split up the dosage.