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chocamine

Lao Tzu

Lao Tzu

New member
I saw Juve mention this drug, so i looked it up. it seems to be like ephedra, so i want to give it a try. Anyone know anything about it? It is really just watered down cocaine? What all alpha/beta receptors does it activate? Does it effect dopamine, serotonin or chemicals like that? Would it give a false positive for cocaine on a drug test?
 
nordstrom said:
I saw Juve mention this drug, so i looked it up. it seems to be like ephedra, so i want to give it a try. Anyone know anything about it? It is really just watered down cocaine? What all alpha/beta receptors does it activate? Does it effect dopamine, serotonin or chemicals like that? Would it give a false positive for cocaine on a drug test?
Click to expand...

It is a concentrated chocolate extract. Chocolate contains caffeine and theobromine, which are methylxanthines that affect adenosine receptors and inhibit phosphodiesterase (not sure what all isoforms of PD). It also contains phenylethylamine, which is a metabolite of phenylalanine and is shown to improve mood. PEA is rapidly deactivated by MAO, though.

There are some novel compounds found in chocolate in very small quantities such as anandamide-mimicking lipids, which bind to cannabanoid receptors.
 
chocamine and selegiline is an awesome combination btw. however, some may find it to be too stimulating.
 
bdog527 said:
chocamine and selegiline is an awesome combination btw. however, some may find it to be too stimulating.
Click to expand...

Yes, selegiline is useful with chocamine, since selegiline is an MAO-B inhibitor and decreases the degradation of the PEA. Cut back on the doses if it becomes to stimulatory.
 
atlantabiolab said:
Yes, selegiline is useful with chocamine, since selegiline is an MAO-B inhibitor and decreases the degradation of the PEA. Cut back on the doses if it becomes to stimulatory.
Click to expand...

MAO inhibitors could be extremely dangerous for people on EF because we take in alot of protein. I dont know how much tyrosine is in whey protein mix but it could be really dangerous. Then again i cant remember the differenece of MAO inhibitors or if each has different effects on blood pressure and tyrosine.
 
nordstrom said:
MAO inhibitors could be extremely dangerous for people on EF because we take in alot of protein. I dont know how much tyrosine is in whey protein mix but it could be really dangerous. Then again i cant remember the differenece of MAO inhibitors or if each has different effects on blood pressure and tyrosine.
Click to expand...

The "cheese effect" is not due to protein or tyrosine, but tyrAMINE, which is found in cheese and a few other foods. Also, selegiline is an MAO-B inhibitor which lacks the potential for this problem, because it is the MAO-A isoform that is involved in this problem. This is a concern with tricyclic's, not so with selegiline.
 
I'm starting selegine/hydergine this month.

I'm also using:

ALCAR @ 7-10g
Choline (cheap bitartrate) @ 5g
Neurogenex @ 3-5/day
Rhodiola @ ~ 2g/day 3%
Bacopa @ 800mg-1g/day
Bromocriptine @ 1mg/day (will cease once selegiline arrives)
Mucuna 15% L-dopa (2-300mg 5x a week)
Pregnenolone @ 100mg/day (just started...going to see how this affects me in terms of downstream metabolite side effects)

In fact, Atlanta...what do you think about using oral pregnenolone for cognitive enchancement...is there a concern about it raising estrogen/progesterone levels in men? I've read conflicting statements.

Help is appreciated. :)
 
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jesus christ, atlantabiolab totally knows his stuff.

abl, are you working in the biotech industry? what kind of products does your company produce?
 
atlantabiolab said:
The "cheese effect" is not due to protein or tyrosine, but tyrAMINE, which is found in cheese and a few other foods. Also, selegiline is an MAO-B inhibitor which lacks the potential for this problem, because it is the MAO-A isoform that is involved in this problem. This is a concern with tricyclic's, not so with selegiline.
Click to expand...

Nice :)
 
Frackal19 said:
Pregnenolone @ 100mg/day (just started...going to see how this affects me in terms of downstream metabolite side effects)

In fact, Atlanta...what do you think about using oral pregnenolone for cognitive enchancement...is there a concern about it raising estrogen/progesterone levels in men? I've read conflicting statements.

Help is appreciated. :)
Click to expand...

Yeah i want info on pregnenolone too. I started taking it a couple weeks ago at a really low dose (like 20mg a day) and i noticed that when i was doing cardio my shirt rubbing against my nipples caused them to itch (it never did that before i used pregnenolone or after i quit), fearing gyno i quit using it but i dont know if converstion to progesterone is what was causing the sensation of itchy nipples.
 
Oral pregnenolone is crap - use transdermal, rub it on your templs, wrists - works great. Maybe make a nasal spray :o

Anyway, atl owned this thread anyways - chocamine + l-deprenyl, is fk'n godlike, in fact l-deprenyl should be used with everything, good stuff.
Try chocamine(2-5g) (this is mainly for PEA) with DL-phenylalanine(500mg), l-Tyrosine (1g),ALCar(1g) and if you have immediate access to l-dep drop that in too=sharp like an assassin, and overall great CNS stimulation , especially for someone like me who will be unphazed with 100mg+ ephedrine in one sitting.


And I don't watch tv, bucko, nothing ever good anyways....:o
 
juve said:
Oral pregnenolone is crap - use transdermal, rub it on your templs, wrists - works great. Maybe make a nasal spray :o

Anyway, atl owned this thread anyways - chocamine + l-deprenyl, is fk'n godlike, in fact l-deprenyl should be used with everything, good stuff.
Try chocamine(2-5g) (this is mainly for PEA) with DL-phenylalanine(500mg), l-Tyrosine (1g),ALCar(1g) and if you have immediate access to l-dep drop that in too=sharp like an assassin, and overall great CNS stimulation , especially for someone like me who will be unphazed with 100mg+ ephedrine in one sitting.


And I don't watch tv, bucko, nothing ever good anyways....:o
Click to expand...

Agreed with the oral problems of pregnenolone. Unlike DHEA, which does make it through hepatic metabolism into the blood, I can't find any info on pregnenolone being bioavailable from oral intake, not to mention my own experiences with it don't seem to confirm that it does. Transdermal would be the next choice and with the availability of transdermal gels and bulk pregnenolone, this is a viable choice. I am playing around with the idea of a cyclodextrin pregnenolone mixed with picamilon or vinpocetine for intranasal use. Also, I have not found any info on PubMed showing that oral intake alters sex hormone levels.

As for deprenyl, do a search for Cyprenyl (or cyprenil). I have not tried it, but I have heard people use it with success and can be purchased online.
 
atlantabiolab said:
Agreed with the oral problems of pregnenolone. Unlike DHEA, which does make it through hepatic metabolism into the blood, I can't find any info on pregnenolone being bioavailable from oral intake, not to mention my own experiences with it don't seem to confirm that it does. Transdermal would be the next choice and with the availability of transdermal gels and bulk pregnenolone, this is a viable choice. I am playing around with the idea of a cyclodextrin pregnenolone mixed with picamilon or vinpocetine for intranasal use. Also, I have not found any info on PubMed showing that oral intake alters sex hormone levels.

As for deprenyl, do a search for Cyprenyl (or cyprenil). I have not tried it, but I have heard people use it with success and can be purchased online.
Click to expand...


selepryl - liquid deprenyl citrate - the stuff I'm using; very cheap at IAS $69~~ for 300mg = highly recommended :)
 
If that's legit that's an awesome deal...


ABL ... just curious, why the combination of pregnenolone, vinpo and picamilon? Some anticipated synergy or just your preferred combination?

I also have some picamilon but I don't think I've noticed a whole lot from it... though I have noticed "some" effect...mild stim + mild tranquilizing as it's claimed to do
 
Frack

why the concern for mental clarity?

your already smart

why the need for more?

sometimes its not such a good thing to be smarter :)

you know that don;t ya :)
 
Genetics are just a starting point.

But it really stems from my whole underlying idealogy of how I govern my life, which is through constant forward motion no matter what category that might be. Brain, looks, academics, career, social ability, knowledge, aspirations, accompishments, etc...
 
Frackal19 said:
If that's legit that's an awesome deal...


ABL ... just curious, why the combination of pregnenolone, vinpo and picamilon? Some anticipated synergy or just your preferred combination?
Click to expand...

Not both vinpocetine and picamilon, but either or. Picamilon is more potent, from the studies I have seen, than vinpocetine in its cerebrovascular effects. Also, picamilon has putative anxiolytic effects, which may mix well with pregnenolone...don't know yet. Last, picamilon is effective in small quantities, 50mg orally, so it would be effective in smaller quantities intranasally.

I have narcolepsy, not the hilarious fall-in-your-food version (cataplexy), but just the constant fatigued version (though I can fall asleep at the drop of a hat). So I play around with potential stimulants to assist in this disorder.
 
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