Take with lemonade or OJ or else cap the powder. Buy 5mg I hope you ment 5000mgs. But actually you should start out take 10000mg and then work your way down 3000mgs. The reason is B5 will cause an intital breakout where you acne will get worse about a week after you start taking it. If you start with 5000mgs and its not enough to slow down your bodies sebum production (oil glands), then you will have to up the dose and when you up the dose you will get a second initial breakout. You wil avoid future breaks if you start higher and work you way down. After this about a month your acne should be gone but if you are prone to acne without gear then you will need to take B5 non stop to get the benefits. You should take B5 4-5 times a day in equal doses because it does not last for more then 3 hours. At least this is what I do. How do the rest of you take B5?