From AST Sports Science ...
Q: A lot of supplement companies claim there is research to support the benefits of adding chrysin to their prohormone supplements. They claim that chrysin eliminates any undesired increase in estrogen levels, is this true?
A: Quite a few years ago, some laboratory test tube (in vitro) studies showed that a chemical called chrysin (5,7-dihydroxyflavone), prevented the conversion of testosterone to estrogen. However, a chemical reaction within a test tube does not mean the same effect will occur within a living body.
Paul Delia posted the results of an invivo (within the living body) study on chrysin last year. The results of this research confirmed that test tube findings can sometimes be a far cry from human experiments. Published in the International Journal of Sport Nutrition & Exercise Metabolism, this study examined the effects of chrysin on serum testosterone concentrations and adaptations to resistance training in healthy young men. The scientists specifically wanted to see if chrysin or indol-3-Carbinol increased testosterone levels or reduced the aromatization effects of androstenedione (a prohormone).
The study revealed that chrysin did not result in increased serum testosterone concentrations or reduce the estrogenic effect of androstenedione. Also, chrysin did not enhance the results of resistance training.
Even though the science shows chrysin is not effective, supplement companies still include this compound in their prohormone supplements. Why? It is a result of what Paul Delia appropriately terms the "monkey see - monkey do" syndrome that is rampant in the supplement industry.
This means if a supplement company spends a ton of money on marketing a useless supplement that is supported by absolutely no research, other "me too" companies will still copy the worthless product and sell it under their own name. Many supplement companies do this in a lame attempt to provide the consumer with something “new”, regardless of whether the compound is effective or not. It happens all the time. It’s a case of the crooks leading the stupid. The fact is that no human or animal research shows that chrysin possesses any ability whatsoever to bind to estrogen or prevent estrogen production.
Q: I read where you say Chrysin does not prevent aromatization and should not be taken with androstenedione. How come every other company sells andro supplements with chrysin in them and says that it does help reduce aromatization and also boosts testosterone?
A: We have said this for quite a few years now. Chrysin is a worthless supplement and should never be taken with ando supplements. In fact, a recent study unequivically proved this.
In the International Journal of Sport Nutrition & Exercise Metabolism, the study, "Effects of Anabolic Precursors on Serum Testosterone Concentrations and Adaptations to Resistance Training in Young Men." was put together to see specifically if chrysin or indol-3-Carbinol increased the testosterone elevating effects and/or reduced the aromatization effects of androstenedione.
Using the supplement Andro-6, the study concluded that, " . . . addition of these herbal extracts (chrysin) to androstenedione does not result in increased serum testosterone concentrations, reduce the estrogenic effect of androstenedione, and does not augment the adaptations to resistance training."
As to why all the other supplement companies sell worthless andro concoctions with chrysin in them is simple. They do no research at all. They are "monkey see - monkey do" operations. It works like this; If a company comes out with a stupid supplement supported by no research but spends tons of money marketing the worthless supplement, other "me too" companies will knock the worthless product off and sell it under their own name. It happens all the time. It's the blind leading the blind.
It's pathetic but it's very prevelent in the sports nutrtion industry.
Effects of Anabolic Precursors on Serum Testosterone Concentrations and Adaptations to Resistance Training in Young Men. International Journal of Sport Nutrition & Exercise Metabolism, 10 (3).
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