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Ala Vs R-ala
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Themachine01
New member
which program are you starting and when did you start?
The_Eviscerator
New member
Either one is OK, but R-ALA is better. If you use 100mg per 25 grams of carbs consumed, just get a couple bottles of some quality R-ala and use it wisely.
Another cool product for glucose disposal is SAN's Loaded. I may throw that into the mix on my PW meals in the near future.
Another cool product for glucose disposal is SAN's Loaded. I may throw that into the mix on my PW meals in the near future.
bicepts101
New member
The_Eviscerator said:
throw bioton into the mix too
https://www.anabolicfitness.net/ALA/index_1.htm
We're finding - and others are, too - that the R(+)-form - the natural form - is much more powerful than the racemic mixture ... Hopefully ... companies are going to be producing on more of a clinical scale the R(+)-form of lipoic acid, because we're finding very significant effects using this, as opposed to the racemic mixture."
Dr. Tory Hagen, in Mitochondrial Decay in Aging.
"We have presented in this study new information indicating that this enhancement of glucose metabolism is sterospecific, with the R(+)-enantiomer being much more effective than the S(-)- enantiomer."
Dr. Ryan Streeper and colleagues, in The American Journal of Physiology.
"Lipoic acid sold in a health food store is a synthetic mixture, a racemic mixture. And R[+]- is the natural form and S[-]- is an unnatural one ... And in our hands R[+]- works and S[-]- doesn't."
Dr. Bruce Ames, in Strategies for Engineered Negligible Senescence.
"R[+]-LA [that is, R(+)-lipoic acid], and not a racemic mixture of R[+]-and S[-]- LA, should be considered a choice for therapeutic applications."
Dr. Lester Packer and colleagues, in Free Radical Biology and Medicine.
"The S[-]-enantiomer … part of the racemate, which is present as about a 50% impurity, needs to be eliminated."
Dr. Guido Zimmer and colleagues, in Methods in Enzymoogy.
We're finding - and others are, too - that the R(+)-form - the natural form - is much more powerful than the racemic mixture ... Hopefully ... companies are going to be producing on more of a clinical scale the R(+)-form of lipoic acid, because we're finding very significant effects using this, as opposed to the racemic mixture."
Dr. Tory Hagen, in Mitochondrial Decay in Aging.
"We have presented in this study new information indicating that this enhancement of glucose metabolism is sterospecific, with the R(+)-enantiomer being much more effective than the S(-)- enantiomer."
Dr. Ryan Streeper and colleagues, in The American Journal of Physiology.
"Lipoic acid sold in a health food store is a synthetic mixture, a racemic mixture. And R[+]- is the natural form and S[-]- is an unnatural one ... And in our hands R[+]- works and S[-]- doesn't."
Dr. Bruce Ames, in Strategies for Engineered Negligible Senescence.
"R[+]-LA [that is, R(+)-lipoic acid], and not a racemic mixture of R[+]-and S[-]- LA, should be considered a choice for therapeutic applications."
Dr. Lester Packer and colleagues, in Free Radical Biology and Medicine.
"The S[-]-enantiomer … part of the racemate, which is present as about a 50% impurity, needs to be eliminated."
Dr. Guido Zimmer and colleagues, in Methods in Enzymoogy.
Dial_tone said:
If "Brand X" buys 97% purity to put in their capsules they can still call it R-ALA. But the 99.9%, which is what is in Glucorell R costs twice as much as 97%. Mainly because the 97% is used for livestock not humans, I assume because the livestock are not as sensitive to the difference as we are. A fact I just learned last week. I always saw it was much cheaper on their price lists but I had never inquired what the chemical companies were doing with the 97% or why they bothered making it. In a conversation with "Jimmy" at MTC in New York about purity he told me why, so now I know.
Point 2: Because the other 3% of the 97% is S-ALA, which will inhibit the effects of the R-ALA, you've defeated the whole purpose of buying R-ALA in the first place.
A
Animal
Guest
So you are saying that 3% messes up the whole batch and makes it as bad as racemic? Studies?
'Because the other 3% of the 97% is S-ALA, which will inhibit the effects of the R-ALA, you've defeated the whole purpose of buying R-ALA in the first place.'
And of course it's just 'speculation':
'There is speculation that caps may be less effective than powder due to heating that may occur during the commercial encapsulation process'
'Because the other 3% of the 97% is S-ALA, which will inhibit the effects of the R-ALA, you've defeated the whole purpose of buying R-ALA in the first place.'
And of course it's just 'speculation':
'There is speculation that caps may be less effective than powder due to heating that may occur during the commercial encapsulation process'
"So you are saying that 3% messes up the whole batch and makes it as bad as racemic?"
No, there are no studies to show ratios, only that the S inhibits, and as I remember, competes with R.
According the tests we've done on Glucorell R before and after bottling the encapsulation process doesn't affect the material. Neither does short term (an hour) exposure to heat under 103 deg. At 105 deg, it's shot.
No, there are no studies to show ratios, only that the S inhibits, and as I remember, competes with R.
According the tests we've done on Glucorell R before and after bottling the encapsulation process doesn't affect the material. Neither does short term (an hour) exposure to heat under 103 deg. At 105 deg, it's shot.
junk
New member
Honestly, I don't think there is THAT MUCH of a difference
between 97% and 99.9%. But I may be wrong.
The primary reason I prefer GlucorellR over other r-ALAs is that
1) I trust those people (Ulter & Macro). Yes, true they want
to sell their products which is totally legit, but I think they
are more commited to quality then any other website I know of.
I feel I can sleep well taking their products. I have a question for
you: Would you feel better and sleep better knowing you took
Schering Testoviron bought from a pharmacy accross the street
than you would taking some UG lab enathate bought for half
the price ? Get the point?
2) I know anabolicfitness invests quite sometime in making
new innovations and spending time making better products.
In order to support them, as opposed to other who just copycat
I say buy from them EVEN if (but it's not) more expensive.
3) GlucorellR has Biotin in it. True, Biotin is cheap and you can
add it yourself, but it's more convenient it's already capped with
the r-ALA
4) Their customer service proved excellent to me.
BTW: I don't have any shares at the afstore
between 97% and 99.9%. But I may be wrong.
The primary reason I prefer GlucorellR over other r-ALAs is that
1) I trust those people (Ulter & Macro). Yes, true they want
to sell their products which is totally legit, but I think they
are more commited to quality then any other website I know of.
I feel I can sleep well taking their products. I have a question for
you: Would you feel better and sleep better knowing you took
Schering Testoviron bought from a pharmacy accross the street
than you would taking some UG lab enathate bought for half
the price ? Get the point?
2) I know anabolicfitness invests quite sometime in making
new innovations and spending time making better products.
In order to support them, as opposed to other who just copycat
I say buy from them EVEN if (but it's not) more expensive.
3) GlucorellR has Biotin in it. True, Biotin is cheap and you can
add it yourself, but it's more convenient it's already capped with
the r-ALA
4) Their customer service proved excellent to me.
BTW: I don't have any shares at the afstore
L
lartinos
Guest
vitamin shoppe brand has r-ala, biotin, and chromium in it. I decided to give the AF r-ala a shot as i have been very happy with the other two products I've ordered. (yohimburn, p-7)
L
lartinos
Guest
whoops, i meant that vitamin shoppe has ala, biotin, and chromium in it. Anybody else supplement chromium with ala/r-ala
A
Animal
Guest
Ok, wait, S works on some different things than R and R works on some different things than S fpr example, S has a unique ability to work on RBC's which R doesn't and yes, I know of 'competition' and 'inhibits', but is it (S) inhibiting R while actually imparting it's own benefits or do they both cancel each other out?
I know there are a multitude of studies, but I don't recall them looking for benefits exerted by S which could be different from R when a racemic was used.
I know there are a multitude of studies, but I don't recall them looking for benefits exerted by S which could be different from R when a racemic was used.
You should look closer at Dr Burt Berkson's work, he's written two books, runs a clinic in NM, teaches at the UNM and has several papers published. He was the FDA's lead investigator of ALA for 20 years. My point being he's an authority. When I was lucky enough to speak to him from his home in NM he said that he would not switch to the R+ for the treating his Hepatitis patients. Even though Dr L Packer (the world's foremost authority on anti-oxidants) and Dr B Ames (see: Ames index) BOTH implored him to begin using R+. I even sent him a case of Glucorell R so he could try it. He won't. He told me that the racemate and the S are too important to be left out. But to my knowledge he is the only one left that still believes that. Some people are hard headed, something you don’t know anything about. Now, that said, his work is strictly with Liver Disease, an area that neither Packer nor Ames has done much work in. Packer being more interested in glucose uptake and Ames in Cancer prevention. There is actually some older work that was done in Europe with S only that is published in German and Russian under the name thioctic. You'll need to get them translated though. The most remarkable being the one where the Russian's gave racemate to the clean up workers at Chernobyl and the workers that received it didn't get any of the cancers or leukemia that the ones who were untreated developed. It was published in Russian as a 15 year follow up review to the accident. Again, it’s in Russian.
In the mean time, I will continue to go with the research done at USC and Berkley, and that research all says that the R+ is far more powerful and less invasive because it is after all the natural form of Lipoic and the body treats it as a friend rather than a foreign substance. I will email you Dr Packer’s paper which breaks it all down.
I am sending it to your hotmail [email protected] account
In the mean time, I will continue to go with the research done at USC and Berkley, and that research all says that the R+ is far more powerful and less invasive because it is after all the natural form of Lipoic and the body treats it as a friend rather than a foreign substance. I will email you Dr Packer’s paper which breaks it all down.
I am sending it to your hotmail [email protected] account
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