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Acne all you need to know.

  • Thread starter Thread starter ryker77
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ryker77

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Acne vulgaris (acne) is a common skin condition that can affect people of all ages, although teenagers develop acne most often. Acne is a disorder that occurs when the sebaceous glands in a person's skin make too much oil (sebum). The oil combines with cells that line the walls of these glands and clogs the person's skin pores.

It is not clear what causes a person's body to produce too much oil or not properly shed dead skin cells. Vitamin B5 might help with oily skin. Outbreaks of acne may be linked to hormones, genetics, or bacteria.1 Acne is not caused by eating too much chocolate or oily foods.

Acne can range from mild to severe. A person may have only occasional bouts with acne or it may be constant. Treatment for acne is based on the severity of the outbreak and how much it affects a person's appearance.

The goal of treatment is to reduce or eliminate outbreaks and to prevent scarring. Home care of acne and use of nonprescription medications can be effective. Prescribed oral medications (such as isotretinoin) and topical medications (such as benzoyl peroxide) are also available to treat acne. Usually, a combination of medications is most helpful.

Treatments read this part!! If you go to a general doctor you'll get poor service. You'll need to be able to tell him that you want to try ### and some of ###. Or just go to a dermatoligist.

Medications do not cure acne, but they can help manage the severity and frequency of outbreaks. Different medications are used, depending on the type of acne (pimples, whiteheads, blackheads, or cystic lesions). The types of medications used most often to treat acne include those that:

Help unplug skin pores and stop them from getting plugged with oil (such as tretinoin [sold as Retin-A]).
Kill bacteria, such as antibiotics and lotions that contain sodium sulfacetamide.
Reduce the amount of sebum made by a person's body (such as isotretinoin [sold as Accutane]).
Reduce the effects of hormones in producing acne (such as oral contraceptive pills for women).
The best medical treatment for acne often consists of a combination of medications. Some medications are combined into one product, such as Benzamycin topical gel which contains an antibiotic (erythromycin) and benzoyl peroxide, or BenzaClin topical gel, which contains benzoyl peroxide and the antibiotic clindamycin. Other times, two different medications are needed. For example, some people use benzoyl peroxide lotion or gel in the morning and tretinoin (Retin-A) at bedtime.

The most common types of medications used to treat acne include:

Antibiotics, such as erythromycin (E-Mycin) and tetracycline.

Tretinoin (Retin-A) and adapalene (Differin), both retinoid medications.

Other retinoids, such as isotretinoin (Accutane) and tazarotene (Tazorac).

Certain hormones, such as estrogen (low-dose birth control pills).

Sodium sulfacetamide, such as Klaron lotion, Novacet lotion, and Sulfacet-R lotion.

Azelaic acid, such as Azelex, a topical cream.
 
Antibiotics for acne

Antibiotics for acne

Antibiotics are often used to treat severe acne or acne that is likely to leave scars. Antibiotics reduce the number of pimples and the amount of redness around pimples. Antibiotics also may reduce overall inflammation of a person's skin. This results in less acne scarring.

Antibiotics can be applied directly to your skin (topically) or taken by mouth (orally). Topical antibiotics kill bacteria that are on your skin. Oral antibiotics kill bacteria in your skin pores. Oral antibiotics work best if they are started at high doses. The dose is reduced when acne gets better.

People with mild acne may only need topical antibiotics. The most common include:

Erythromycin (E-Mycin).
Clindamycin hydrochloride (Cleocin).
People with severe acne and people who are more prone to scarring from acne often take antibiotics by mouth. The most common oral antibiotics include:

Tetracycline hydrochloride (Achromycin).
Erythromycin (E-Mycin).
Doxycycline (Vibramycin, Monodox).
Minocycline hydrochloride (Minocin).
Trimethoprim-sulfamethoxazole (Bactrim, Septra).
Amoxicillin (Amoxil).
An antibiotic that works for one person with acne may not work for another. Over time, antibiotics can stop being effective. When this occurs, a different antibiotic may be used. For example, oral doxycycline may be used for a person whose acne is no longer helped by oral erythromycin. Oral minocycline may be used for a person whose acne has gotten worse while taking oral tetracycline.

Please not that most orals medications will require you to not eat or drink milk type foods for 1-3 hours. Also any type of vit A, E zinc and a few others will hinder its performance. So most orals are useless for us meatheads.
 
Tretinoin (Retin-A)

Tretinoin (Retin-A)


Tretinoin (Retin-A) is very effective for treating whiteheads and blackheads. Tretinoin is made from vitamin A and is sometimes called vitamin A acid or retinoic acid.

Tretinoin comes in cream, gel, and liquid forms. Apply it to the skin once a day, usually at night, about 20 to 30 minutes after washing your face.

Tretinoin works best if you start with a lower strength and change to a higher strength as needed. Doing this may reduce the amount of redness and peeling of your skin.
You may need to use tretinoin for as long as 6 weeks before you notice any improvement in your skin condition.
At first, tretinoin may make acne worse. You may notice redness and peeling of your skin when you first use tretinoin.

Some people use benzoyl peroxide for 2 to 3 weeks before starting tretinoin. This may prevent your acne from getting worse when you start using tretinoin.

Using tretinoin along with other products such as benzoyl peroxide or antibiotic lotion or gel may be more successful than using tretinoin alone.

Side effects of tretinoin include:

Sensitivity to sunlight.
Dryness or excessive redness and peeling of the skin.
If your skin becomes very red and peels, try using tretinoin every other night or every third night instead of every night.

I like the gel because the cream is very oily. Yet the cream can come in a stronger strenght.
 
Adapalene (Differin)

Adapalene (Differin)

Adapalene (Differin) is an effective treatment for whiteheads, blackheads, and pimples. It is made from vitamin A, just like tretinoin. Adapalene usually is applied directly to the skin once a day in the evening.

At first, adapalene may seem to make acne worse. However, with continued use, adapalene usually begins to clear up acne in 2 to 3 weeks. Some people need to use it for as long as 6 weeks before they notice any improvement in their acne.

Side effects of adapalene may include:

Sensitivity to sunlight.
Dryness or excessive redness and peeling of the skin.
Some helpful hints when using adapalene:

Always wash the affected skin before applying adapalene.
Avoid getting it near your mouth and on the skin directly under your nose.
Avoid direct sunlight as much as possible. Use sunscreens (with an SPF of at least 15) and protective clothing such as hats or visors and long-sleeved shirts when you are in the sunlight.
Avoid sunlamps, because the ultraviolet rays are similar to those of sunlight and can damage your skin.
If your skin becomes very red and peels, use adapalene every other night or every third night instead of every night.
 
isotretinoin (Accutane) tazarotene (Tazorac)

Other retinoids for acne vulgaris isotretinoin (Accutane) tazarotene (Tazorac)

Retinoid medications are made from vitamin A and can be used to treat severe acne. Retinoid medications are usually taken by mouth, although in Europe they are available in a topical cream. People usually need to take this medication for 3 to 6 months.

How It Works

Retinoids work by unclogging skin pores and shrinking oil glands to a very small size.

Why It Is Used

Retinoids are used to treat people who:

Have severe acne that did not get better with other treatments.
Develop scars (particularly deep scars) after their pimples or cystic lesions heal.

Making the decision about taking isotretinoin (Accutane) for severe acne

How Well It Works

In most people, acne goes away or improves within 4 to 5 months after starting retinoid medication.

Some people who take this medication are free of acne for years after they stop using it. If a person's acne returns after he or she stops using isotretinoin or tazarotene, the acne usually is not as bad as it once was.

Side Effects

Retinoid medications may have side effects, such as:

Miscarriage and serious birth defects. The most dangerous side effect of retinoid medication is miscarriage and serious birth defects in babies whose mothers took the medication during pregnancy. Women who can have children need to take special precautions so that they do not become pregnant while they are taking retinoid medication. The risk of birth defects and miscarriages goes away about 1 month after the medication is stopped.

Increase in triglycerides in the blood. A person who takes retinoid medication may have higher than normal levels of certain fats (triglycerides) in his or her blood. High levels of triglycerides may make a person more prone to certain health problems, such as heart disease. For this reason, all people need to have their blood checked for triglyceride levels before starting this medication and every 4 to 6 weeks while taking it.

Changes in mood or thoughts. Some people who take retinoid meciations may have changes in their moods (such as depression) or become confused and lose touch with reality. Rarely, a person may have thoughts of suicide. It is not clear why this occurs. It may be related to too much vitamin A in a person's body. These symptoms go away when the medication is stopped.

Liver damage. Some people who have certain liver conditions may develop liver damage if they take retinoid medication. For this reason, all people need to have blood tests to check their liver function before starting this medication. People with liver problems need to have blood tests to check their liver function during treatment with retinoid medication.

Other side effects. Other common side effects of retinoid medications can include chapped lips, dry skin, dry eyes, and dryness inside the nose and mouth. People also complain of fatigue, sensitivity to the sun, problems with night vision, and thinning of hair.

Thnking about accutane click:
http://content.health.msn.com/encyclopedia/article/4115.13017#aa37467-intro
 
Certain hormones for acne

Not really for us. But good for your GF or SO.
Certain hormones for acne


Certain hormones that prevent the body from producing testosterone can be used to treat acne. They are only used in women because men need testosterone for normal sexual activity.

The most common hormone taken by mouth is estrogen, in the form of low-dose birth control pills.

Rarely, other hormones, including dexamethasone and prednisone, are used in acne treatment.

Hormones have many side effects and are used to treat severe acne only for short periods of time.
 
Sodium sulfacetamide for acne

Lotions that contain sodium sulfacetamide can be used to treat acne. They kill bacteria on your skin when applied directly to your skin.

The most common lotion that contains only sodium sulfacetamide is Klaron Lotion.

Other lotions also contain sulfur and include:

Novacet.
Sulfacet-R.

Side effects of lotions that contain sodium sulfacetamide are rare. However, the lotions may irritate some people's skin, causing it to become very red and dry. Other people may have problems breathing after using lotions that contain sodium sulfacetamide.
 
Azelaic acid for acne vulgaris

Azelaic acid for acne vulgaris

How It Works

Azelaic acid is a naturally occurring substance that acts as an antibacterial against acne vulgaris. It is used as a topical cream that works by inhibiting the growth of bacteria in the skin.

Why It Is Used

Azelaic acid is used to slow down the growth of bacteria and reduce inflammation in acne vulgaris. It may also be used to treat the bacteria that causes acne (P. acnes) that does not respond to other medications.

How Well It Works

Azelaic acid works well in mild to moderate outbreaks of acne. It does not work well for acne that is not inflamed or is not associated with a bacteria. A decrease in the number of inflamed acne lesions usually occurs 1 to 2 months after applying the cream.

Side Effects

Azelaic acid should not be applied to the eye, mouth, or other mucous membranes. This product is not approved for use in children under the age of 12 years.

What to Think About

Topical azelaic acid can be used to treat stubborn acne for up to 1 year; however, some doctors recommend that it not be used for longer than 6-month intervals. Limited studies indicate azelaic acid may be as effective as oral tetracycline hydrochloride without the many potential negative side effects.

Probably not good for us meatheads. Since are acne comes from oily skin.
 
A / T / S

Company
Medicis

Pharmacologic Class
Macrolide antibiotic.

Generic Name
Erythromycin

Available as
A/T/S SOLUTION
(erythromycin 2%, alcohol 66%)
A/T/S GEL
(erythromycin 2%, alcohol 92%)

Indications
Acne vulgaris.

Adults
Solution: Apply with applicator or pad to cleansed area twice daily.
Gel: Apply sparingly to cleansed area twice daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes and mucous membranes. Pregnancy (Category B).
Nursing mothers: Not recommended.

Interactions
Additive irritation with other topical agents (esp. abrasives or keratolytics).

Adverse Reactions
Superinfection, dryness, scaly skin, pruritus, urticaria, erythema, oiliness, burning sensation.

How Supplied

Soln–60mL
Gel–30g
 
ACCUTANE

Company
Roche

Pharmacologic Class
Retinoid.

Generic Name
Isotretinoin

Available as
Isotretinoin 10mg, 20mg, 40mg; capsules; contains parabens.

Indications
Severe recalcitrant nodular acne unresponsive to conventional therapy, including systemic antibiotics.

Adults
Take with meals. 0.5-1mg/kg per day in 2 divided doses; treat for 15-20 weeks or less if nodule count reduced by >70%; max 2mg/kg per day. Repeat course only if necessary after at least 2 months drug-free interval.

Children
Not applicable.

Contraindications
Pregnancy (Category X). Nursing mothers. Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Be fully familiar with drug's toxicity before use. Counsel patient about need for contraception; obtain 2 negative pregnancy tests prior to initiation of drug and monthly thereafter; use 2 effective methods of contraception 1 month before, during, and 1 month after therapy; get written informed consent. Monitor blood lipids initially and for 1st 4 weeks. Osteoporosis risk (eg, osteomalacia, anorexia nervosa). Monitor bone growth, glucose, sed rate, CBC, liver enzymes. Discontinue if visual or auditory disturbances; colitis, pancreatitis or hepatitis symptoms; uncontrolled hypertriglyceridemia, or significant decrease in WBCs occurs. Refer to specialist if papilledema or hearing disturbances occurs. Do not donate blood during and for 1 month after therapy. Avoid wax epilation or skin resurfacing during and for 6 months after therapy. Adolescents. Avoid sun, UV light. Decreased tolerance to contact lenses. Max 1 month/Rx.

Interactions
Avoid tetracyclines (increased risk of pseudotumor cerebri), Vit. A, or alcohol consumption. Avoid St. John's wort with hormonal contraceptives. Low-dose progestin-only contraceptives (ie, minipills) may provide inadequate contraception. Caution with drugs that can disturb bone metabolism (eg, anticonvulsants, systemic corticosteroids).

Adverse Reactions
Dry skin, eyes, nose, mouth, and lips, transient exacerbation of acne, dizziness, drowsiness, headache, abnormal menses, bronchospasm, voice alterations, alopecia, epistaxis, flushing, hirsutism, rash, GI disturbances, photosensitivity, abnormal wound healing, depression, psychosis, suicidal ideation, pseudotumor cerebri, pancreatitis; visual, auditory, or lipid disturbances; hepatotoxicity, inflammatory bowel disease, osteopenia, osteoporosis, hyperostosis, premature epiphyseal closure, reversible corneal opacities, decreased night vision, musculoskeletal symptoms (eg, arthralgia), back/chest pain, blood dyscrasias, glucose intolerance, palpitation, thrombotic disease.

How Supplied
Caps–10 x 10 (Rx packs)
 
ACHROMYCIN V

Company
Stada

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Tetracycline

Available as
Tetracycline HCl 250mg, 500mg; capsules.

Indications
Adjunct in severe acne.

Adults
Initially 1g daily in 2-4 divided doses, then 125-500mg daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Renal impairment. Monitor blood, renal and liver function in long-term use. Sun or UV light. Pregnancy, Nursing mothers: Not recommended.

Interactions
Avoid methoxyflurane, photosensitizing agents. May antagonize bactericidal antibiotics. May increase serum digoxin levels. Reduced absorption with antacids, iron, zinc, calcium, magnesium, dairy products, urinary alkalinizers, other multivalent cations. May reduce effectiveness
of oral contraceptives. Monitor prothrombin time with oral anticoagulants.

Adverse Reactions
Nausea, dizziness, rash, blood dyscrasias, pseudotumor cerebri, photosensitivity, increased BUN, hepatotoxicity.

How Supplied
Caps: 250mg–40, 100, 1000
500mg–100, 1000
 
AVITA

Company
Bertek

Pharmacologic Class
Retinoid.

Generic Name
Tretinoin

Available as
Tretinoin 0.025%; cream; gel.

Indications
Acne vulgaris.

Adults
Apply sparingly to cleansed and completely dry skin once daily
at bedtime. If irritation develops, may reduce the dosing frequency.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Not for use in eczema or on sunburned skin.
Minimize exposure to sun, UV light, weather extremes.
Avoid eyes, mouth, angles of nose, mucous membranes.
Pregnancy (Category C) Nursing mothers: Not recommended.

Interactions
Allow effects of benzoyl peroxide, sulfur, resorcinol, salicylic acid, other topical acne agents to subside before applying. Avoid keratolytics, abrasives, astringents, drying agents, high-alcohol content topical products, spices, lime.

Adverse Reactions
Apparent exacerbation of symptoms, local skin reactions
(including erythema, edema, blistering, crusting), transient
pigmentation changes, stinging on application, dry skin.

How Supplied
Cream, gel–20g, 45g
 
AZELEX

Company
Allergan Herbert

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Azelaic acid

Available as
Azelaic acid 20%; cream.

Indications
Mild to moderate inflammatory acne vulgaris.

Adults
Wash and dry skin. Massage thin film gently into affected areas twice daily (AM and PM). Wash hands after use. If persistent irritation occurs, may decrease to once daily.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Monitor patients with dark complexions for hypopigmentation. Discontinue if sensitivity or severe irritation develops. Avoid mouth, eyes, other mucous membranes, and occlusive dressings. Pregnancy (Category B). Nursing mothers.

Adverse Reactions
Pruritus, burning, stinging, tingling; rare: exacerbation of asthma or of recurrent herpes labialis, vitiligo depigmentation, small depigmented spots, hypertrichosis, reddening.

How Supplied
Crm–30g, 50g
 
BENZAC

BENZAC
Company
Galderma

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as
Benzoyl peroxide 5%, 10%, alcohol 12%; gel.

Indications
Acne.

Adults
Initially apply to cleansed area once daily, increase to 2-3 times daily
as tolerated.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, mouth, and mucous membranes.
Pregnancy (Category C). Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive drying, allergic dermatitis, may bleach fabrics or hair.

How Supplied
Gel–60g
 
Alpha Lipoic acid, both the racemic and r version helped quite a bit with my acne. So does an EFA supplement to keep skin smooth. Face acne here.
 
BENZAC-W

BENZAC-W

Company
Galderma

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as
BENZAC-W GEL
(benzoyl peroxide 2.5%, 5%, 10%; aqueous-base gel)
BENZAC-W WASH
(benzoyl peroxide 5%, 10%; cleansing solution)

Indications
Acne.

Adults
Gel: Initially apply to cleansed area once daily,
increase to 2-3 times daily as tolerated.
Wash: Wash affected area 1-2 times a day. Rinse off.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Avoid eyes, mouth, and mucous membranes. Pregnancy
(Category C). Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive drying, allergic dermatitis, may bleach fabrics or hair.

How Supplied
W Gel–60g
Wash 5%–4oz, 8oz
10%–8oz
 
BENZACLIN

BENZACLIN
Company
Dermik

Pharmacologic Class
Lincosamide antibiotic + antibacterial/keratolytic.

Generic Name
Clindamycin + Benzoyl peroxide

Available as
Clindamycin (as phosphate) 1%, benzoyl peroxide 5%; gel.

Indications
Topical treatment of acne vulgaris.

Adults
Apply twice daily.

Children
Not recommended.

Contraindications
History of regional enteritis, ulcerative or antibiotic-associated colitis.

Precautions
Avoid eyes, mucous membranes. Discontinue if significant diarrhea occurs. Pregnancy (Category C). Nursing mothers: Not recommended.

Interactions
Additive irritation with other topical agents. Avoid erythromycin.

Adverse Reactions
Dry skin, application site reaction, pruritus, peeling, erythema, sun-burn; superinfection, colitis (rare); may bleach fabrics or hair.

How Supplied
Gel-25g, 50g
 
BENZAGEL

BENZAGEL
Company
Dermik

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as
BENZAGEL
(Benzoyl peroxide 5%, 10%; alcohol 14%; gel)
BENZAGEL WASH
(Benzoyl peroxide 10%; alcohol 14%; gel)

Indications
Mild to moderate acne.

Adults
Benzagel: Apply sparingly to cleansed and dried area one or more times daily,
as tolerated. Benzagel Wash: Wet skin, wash affected area(s) once or twice daily.
Rinse, pat dry.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, mouth, and mucous membranes.
Discontinue Gel if severe irritation occurs; discontinue Wash if itching, redness, burning, swelling, or undue dryness occurs. May bleach fabrics or hair. Pregnancy (Category C). Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive dryness, allergic or contact dermatitis,
may bleach fabrics or hair.

How Supplied
Benzagel–1.5oz
Benzagel Wash–60g
 
BENZAMYCIN

BENZAMYCIN
Company
Dermik

Pharmacologic Class
Macrolide antibiotic + antibacterial/keratolytic.

Generic Name
Benzoyl peroxide + Erythromycin

Available as
BENZAMYCIN JAR
(Erythromycin 3%, benzoyl peroxide 5%; gel)
BENZAMYCIN PAK
(Erythromycin 3%, benzoyl peroxide 5%; gel)

Indications
Acne vulgaris.

Adults
Apply to cleansed, dried areas twice daily.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
ts class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, mouth, mucous membranes.
Discontinue if excessive irritation or dryness occurs.
Pregnancy (Category C). Nursing mothers.

Interactions
Additive irritation with other topical agents.
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Dryness, local reactions (eg, peeling, pruritus, burning sensation, erythema), superinfection; may bleach hair or fabrics.

How Supplied
Gel (jar, mix before dispensing)–23.3 g, 46.6 g
Pak (pouches, mixed by patient)–60
 
BENZOYL PEROXIDE

BENZOYL PEROXIDE
Company
Various

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as
Benzoyl peroxide 5%, 10%; gel

Indications
Mild to moderate acne.

Adults
Apply sparingly to cleansed and dried area one or more times daily,
as tolerated.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, mouth, and mucous membranes.
Discontinue Gel if sever irritation occurs; discontinue Wash if itching, redness, burning, swelling, or undue dryness occurs.
May bleach fabrics or hair.
Pregnancy (Category C). Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive dryness, allergic or contact dermatitis,
may bleach fabrics or hair.

How Supplied
Gel: 5%–45g
10%–45g, 90g
 
CLEAR BY DESIGN

CLEAR BY DESIGN
Company
GSK Consumer

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as OTC
Benzoyl peroxide 2.5%; gel.

Indications
Acne.

Adults
Apply to cleansed, dry areas of face, neck, and body 1-2 times daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, mucous membranes.
Discontinue if excessive irritation, dryness occurs.

Adverse Reactions
Dry skin, pruritus, irritation.

How Supplied
Gel–1.5oz
 
CLEOCIN T

CLEOCIN T
Company
Pharmacia

Pharmacologic Class
Lincosamide antibiotic

Generic Name
Clindamycin

Available as
Clindamycin (as phosphate) 1%; soln*; pads*; lotion; gel;
*(contains isopropyl alcohol 50%).

Indications
Acne vulgaris.

Adults
Apply thin film twice daily.

Children
Not recommended.

Contraindications
History of regional enteritis, ulcerative or antibiotic associated colitis.

Precautions
Avoid eyes, mouth, abraded skin and mucous membranes.
Atopic patients. Discontinue if significant diarrhea occurs.
Pregnancy (Category B). Nursing mothers.

Interactions
May potentiate neuromuscular blocking agents. Avoid erythromycin.

Adverse Reactions
Dryness, oily skin, burning, erythema, abdominal pain, gram (-) folliculitus, stinging eyes; rare: diarrhea, colitis.

How Supplied Plenty of options
Soln w. applicator–30mL, 60mL
Pledgets (1mL soln/pad)–60
Lotion–60mL
Gel–30g, 60g
 
Topical green tea extract works great for acne...

Management of acne vulgaris with 2% polyphenone (green tea extract) in cream
a placebo-controlled, double-blind study.

T. Syed (1), A. Seyed (2)

(1) Department of Dermatology, University of California San Francisco, Box
0989, CA 94143, USA.
(2) Department of Chemistry, University of California at Berkeley, CA 94720,
USA.

Purpose

To evaluate the safety, tolerability and clinical efficacy of
Epigallocatechin gallate(-EGCg) 2% in cream to treat acne vulgaris.

Methods

Subjects (34M/26F), aged 12-30 years, harboring 10-150 mild-to-moderate,
open or closed comedones, including cystic acne lesions (mean 73) were
randomized into two parallel groups (active and placebo). The diagnosis of
acne vulgaris was established by clinical observations. Each patient
received an identical precoded tube (25g) with instructions on how to
topically apply the trial cream to the entire affected area of the acne
lesions, twice daily for 5 consecutive days per week. The study was
scheduled for 16 weeks with 6 weeks of active treatment. Absence of clinical
signs of acne lesions and inflammation was recorded as treated.

Results

By the end of the treatment 40.0% patients and 42.0% acnes were treated.
Breaking the code revealed, that 2% EGCg cream had cured 73.3% patients and
77.0% lesions, while placebo healed 6.6% patients and 6.7% acnes (2% EGCg
cream vs placebo; p<0.0001).

Conclusion

The findings of the study showed that along with non-objective mild side
effects, Green Tea Extract, (Polyphenone, -EGCg) 2% in cream is safe,
tolerable and significantly more effective than placebo to cure acne
vulgaris in young adolescents.
 
CLINDAGEL

CLINDAGEL
Company
Galderma

Pharmacologic Class
Lincosamide antibiotic

Generic Name
Clindamycin

Available as
Clindamycin (as phosphate) 1%; gel.

Indications
Acne vulgaris.

Adults
Apply thin film once daily.

Children
Not recommended.

Contraindications
History of regional enteritis, ulcerative or antibiotic-associated colitis.

Precautions
Atopic patients. Discontinue if significant diarrhea occurs.
Pregnancy (Category B). Nursing mothers: not recommended.

Interactions
May potentiate neuromuscular blocking agents.

Adverse Reactions
Pruritus, peeling, abdominal pain, GI disturbances, gram (-) folliculitis; rare: diarrhea, colitis.

How Supplied
Gel–42 g, 77 g
 
DESQUAM-X

DESQUAM-X
Company
Westwood Squibb

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as
Benzoyl peroxide 5%, 10%; water-base gel.

Indications
Mild to moderate acne.

Adults
Massage into cleansed area 1-2 times daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Avoid eyes, mouth, mucous membranes. Pregnancy
(Category C). Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive drying, allergic dermatitis, may bleach fabrics or hair.

How Supplied
Gel–1.5oz, 3oz
 
DESQUAM-X WASH

DESQUAM-X WASH

Company
Westwood Squibb

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as
DESQUAM-X WASH
(Benzoyl peroxide 5%, 10%; water-base cleanser)
DESQUAM-X 10 BAR
(Benzoyl peroxide 10%)

Indications
Acne.

Adults
Bar: Wash for 1-2 minutes 2-3 times daily. Rinse well. Wash: Wet skin, apply, work to full lather, rinse and pat dry 1-2 times daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Avoid eyes, mouth, mucous membranes. Pregnancy (Category C).
Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive drying, allergic dermatitis, may bleach fabrics or hair.

How Supplied
Wash–5oz
Bar–3.75oz
 
DIFFERIN

DIFFERIN
Company
Galderma

Pharmacologic Class
Retinoid.

Generic Name
Adapalene

Available as
DIFFERIN
(Adapalene 0.1%; gel; cream; alcohol-free)
DIFFERIN SOLUTION
(Adapalene 0.1%; soln; pads; contains alcohol 30%)

Indications
Acne vulgaris.

Adults
Apply to affected areas once daily, at bedtime,
after cleansing the area.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Do not use on cuts, abrasions, or broken, eczematous, or sunburned skin. Avoid contact with eyes, lips, angles of the nose, mucous membranes. Minimize exposure to sun and UV light. Increased irritation in extreme weather (eg, wind, cold). Concomitant use of other topical irritants (see Interactions). Reduce frequency or discontinue if prolonged or severe irritation occurs. Pregnancy (Category C). Nursing mothers.

Interactions
Avoid use until the effects of sulfur, resorcinol, or salicylic acid have subsided. Increased irritation with other potentially irritating topical products (eg, medicated or abrasive soaps and cleansers, soaps
and cosmetics that have a strong drying effect, products with high concentrations of alcohol, astringents, spices, lime).
Avoid waxing treated areas.

Adverse Reactions
Erythema, scaling, dryness, pruritus, burning, acne flares.

How Supplied
Gel, cream–15g, 45g
Soln w. applicator–30mL
Pledgets, 1mL soln/pad–60
 
DORYX

DORYX
Company
Warner Chilcott

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Doxycycline

Available as
Doxycycline (as hyclate) 75mg, 100mg; coated pellets in capsules.

Indications
Adjunct in severe acne.

Adults
100mg every 12 hrs for 1 day, then 100mg daily;
reduce dose after improvement. Take with fluids.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Monitor blood, renal, and hepatic function in long-term use.
Sunlight or UV light. Pregnancy (Category D), Nursing mothers: Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption. Avoid concomitant penicillins, methoxyflurane. Carbamazepine, hydantoins decrease effectiveness. Monitor prothrombin time with oral anticoagulants. Oral contraceptives may be less effective.

Adverse Reactions
Photosensitivity, GI upset, rash, blood dyscrasias, hepatotoxicity.

How Supplied
Caps 75mg–60
100mg–50
 
DOXYCYCLINE

DOXYCYCLINE
Company
Various

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Doxycycline

Available as
Doxycycline (as hyclate) 50mg, 100mg
capsules or 100mg tablets

Indications
Adjunct in severe acne.

Adults
100 mg every 12 hours for first day, then 100mg daily in 1 or 2 divided doses. Reduce dose after improvement.
Take with fluids.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Monitor blood, renal and hepatic function in long-term use.
Avoid sun and UV light. Asthma (syrup).
Pregnancy (Category D), Nursing mothers: Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption.
Avoid concomitant penicillins, methoxyflurane.
Carbamazepine, hydantoins may decrease effectiveness.
Monitor prothrombin time with oral anticoagulants.
Oral contraceptives may be less effective.

Adverse Reactions
Superinfection, photosensitivity, GI upset, enterocolitis, rash, blood dyscrasias, hepatotoxicity.

How Supplied
Caps: 50mg–50, 100
100mg–50, 100
Tabs: 100mg–50, 200
 
EMGEL

EMGEL
Company
Elan

Pharmacologic Class
Macrolide antibiotic.

Generic Name
Erythromycin

Available as
Erythromycin 2%, alcohol 77%; gel

Indications
Acne vulgaris.

Adults
Apply sparingly to cleansed dry area as thin layer twice daily (AM & PM).
Wash hands after application.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, mucous membranes. Reevaluate if no improvement after 8 weeks. Pregnancy (Category B). Nursing mothers: Not recommended.

Interactions
Possible additive irritation with other topical acne agents
(esp. abrasives or keratolytics).

Adverse Reactions
Superinfection, burning, peeling, dryness, pruritus, erythema, oiliness, urticaria.

How Supplied
Gel–27g, 50g
 
ERYCETTE

ERYCETTE

Company
Ortho Dermatological

Pharmacologic Class
Macrolide antibiotic.

Generic Name
Erythromycin

Available as
Erythromycin 2%, alcohol 66%; saturated swabs.

Indications
Acne vulgaris.

Adults
Rub over cleansed area twice daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, nose, mouth, and mucous membranes.
Pregnancy (Category C). Nursing mothers.

Interactions
Additive irritation with other topical agents (esp. abrasives or keratolytics).

Adverse Reactions
Superinfection, dryness, scaly skin, pruritus, burning sensation.

How Supplied
Swabs–60
 
ERYTHROMYCIN TOPICAL

ERYTHROMYCIN TOPICAL

Company
Various

Pharmacologic Class
Macrolide antibiotic.

Generic Name
Erythromycin

Available as
Erythromycin 2%, topical solution, gel.

Indications
Acne vulgaris.

Adults
Apply with applicator or pad to cleansed area twice daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes and mucous membranes. Pregnancy (Category B).
Nursing mothers: Not recommended.

Interactions
Additive irritation with other topical agents (especially abrasives or keratolytics).

Adverse Reactions
Superinfection, dryness, scaly skin, pruritus, urticaria, erythema,
oiliness, burning sensation.

How Supplied
Soln–60mL
Gel–30g, 60g
 
FINEVIN

FINEVIN

Company
Berlex

Pharmacologic Class
Antibacterial - keratolytic.

Generic Name
Azelaic acid

Available as
Azelaic acid 20%; cream

Indications
Mild to moderate inflammatory acne vulgaris.

Adults
Wash and dry skin. Massage thin film gently into affected areas twice daily (AM and PM). Wash hands after use. If persistent irritation occurs, reduce to once daily.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Monitor patients with dark complexions for hypopigmentation. Discontinue if sensitivity or severe irritation develops. Avoid mouth, eyes, other mucous membranes, and occlusive dressings. Pregnancy (Category B). Nursing mothers.

Adverse Reactions
Pruritus, burning, stinging, tingling; rare: exacerbation of asthma or of recurrent herpes labialis, vitiligo depigmentation, small depigmented spots, hypertrichosis, reddening.

How Supplied
Cream—30g
 
KLARON

KLARON

Company
Dermik

Pharmacologic Class
Sulfonamide antibiotic.

Generic Name
Sulfacetamide

Available as
Sodium sulfacetamide 10%; lotion.

Indications
Acne vulgaris.

Adults
Apply thin film twice daily to affected areas.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Discontinue if hypersensitivity, skin rash, or irritation occur. Avoid eyes.
Denuded or abraded skin. Asthma. Pregnancy (Category C). Nursing mothers.

Adverse Reactions
Local irritation; severe systemic toxic reactions to sulfonamides
may occur rarely.

How Supplied
Lotion–2oz
 
MINOCIN

MINOCIN

Company
Wyeth

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Minocycline

Available as
MINOCIN CAPSULE
(Minocycline (as HCl) 50mg, 100mg; pellet-filled capsules)
MINOCIN SUSPENSION
(Minocycline (as HCl) 50mg/5mL; custard flavored; contains sulfites and alcohol 5%)

Indications
Adjunct in severe acne resistant to tetracycline and erythromycin.

Adults
Initially 50-200mg daily in 2 divided doses. Reduce dosage after improvement. Take with fluid.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication

Precautions
Renal impairment. Asthma (susp). Monitor blood, renal and hepatic function in long-term use. Pregnancy, Nursing mothers: Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption.
Avoid concomitant penicillins, methoxyflurane.
Monitor prothrombin time with oral anticoagulants.
Oral contraceptives may be less effective.

Adverse Reactions
Nausea, dizziness, rash, blood dyscrasias, pseudotumor cerebri, photosensitivity (rare), increased BUN, hepatotoxicity.

How Supplied
Caps: 50mg–100, 250
100mg–50, 250
Susp–2oz
 
MINOCYCLINE

MINOCYCLINE
Company
Various

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Minocycline

Available as
Minocycline (as HCl) 50mg, 100mg; capsules.

Indications
Adjunct in severe acne resistant to tetracycline and erythromycin.

Adults
Initially 50-200mg daily in 2 divided doses. Reduce dosage after improvement. Take with fluid.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Renal impairment. Monitor blood, renal and hepatic function in long-term use. Pregnancy, Nursing mothers: Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption.
Avoid concomitant penicillins, methoxyflurane.
Monitor prothrombin time with oral anticoagulants.
Oral contraceptives may be less effective.

Adverse Reactions
Nausea, dizziness, rash, blood dyscrasias, superinfection, pseudotumor cerebri, photosensitivity (rare), increased BUN, hepatotoxicity.

How Supplied
Caps: 50mg–100
100mg–50
 
MONODOX

MONODOX
Company
Oclassen

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Doxycycline

Available as
Doxycycline monohydrate 50mg, 100mg; capsules.

Indications
Adjunct in severe acne.

Adults
200mg in 2-4 divided doses for 1 day, then 100mg/day in 1-2 doses.
Reduce dose after improvement. Take with fluid.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Monitor blood, renal, and hepatic function in long-term use.
Sunlight or UV light. Pregnancy (Category D), Nursing mothers:
Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium reduce absorption.
Avoid concomitant penicillins, methoxyflurane.
Carbamazepine, hydantoins, barbiturates may decrease effectiveness.
Monitor prothrombin time with oral anticoagulants.
Oral contraceptives may be less effective.

Adverse Reactions
Superinfection, photosensitivity, GI upset, enterocolitis, rash, blood dyscrasias, hepatotoxicity.

How Supplied
Caps: 50mg–100
100mg–50, 250
 
ORTHO TRI-CYCLEN 28

ORTHO TRI-CYCLEN 28 Just for info not for guys.
Company
Ortho-McNeil

Pharmacologic Class
Progestin + estrogen

Generic Name
Ethinyl estradiol + Norgestimate

Available as
Norgestimate 0.18mg, ethinyl estradiol 35micrograms (7 tabs); norgestimate 0.215mg, ethinyl estradiol 35micrograms (7 tabs); norgestimate 0.25mg, ethinyl estradiol 35micrograms (7 tabs);
inert (7 tabs).

Indications
Moderate acne vulgaris in females, Âł15 years of age,
who have no known contraindications to oral contraceptive therapy,
desire contraception, have achieved menarche and are unresponsive
to topical anti-acne medications.

Adults
Use Day 1 or Sunday start for the first cycle.
1 tablet daily for 28 days; repeat.

Children
Not applicable.

Contraindications
Thrombophlebitis or thromboembolic disorders. Cerebral vascular or coronary artery disease. Breast or other estrogen-dependent neoplasms. Undiagnosed abnormal genital bleeding. Cholestatic jaundice of pregnancy or jaundice with prior OC use. Hepatic adenoma or carcinoma. Pregnancy (Category X).

Precautions
Smokers over 35 years of age: Not recommended. Uncontrolled hypertension. Hypertriglyceridemia. Discontinue if jaundice, visual disturbances, migraine or other severe headaches occur. Do regular complete physical exams. May need barrier contraception with Sunday starts or postpartum use (see literature). Nursing mothers: Not recommended.

Interactions
Antagonized by hepatic enzyme inducing drugs (eg, rifampin, carbamazepine, St. John's wort), possibly others. May affect measurement of sex hormone-binding globulin levels.

Adverse Reactions
Hypertension, nausea, vomiting, breakthrough bleeding, amenorrhea, transient delay of ovulation after discontinuation, edema, chloasma, mastodynia, headache, intolerance to contact lenses. Increased risk of gallbladder disease, thromboembolic disorders.

How Supplied
Packs–1
 
PERSA-GEL

PERSA-GEL
Company
J & J Consumer

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as OTC
PERSA-GEL, EXT STR
(Benzoyl peroxide 5%; water-base gel)
PERSA-GEL, MAX STR
(Benzoyl peroxide 10%; water-base gel)

Indications
Acne.

Adults
Apply a thin layer to cleansed area 1-3 times daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Avoid eyes, mouth, mucous membranes. Use with sunscreen. Reduce strength or frequency or discontinue if excessive irritation occurs. Pregnancy (Category C). Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive drying, allergic dermatitis; may bleach fabrics or hair.

How Supplied
Gel–1oz
 
RETIN-A

RETIN-A
Company
Ortho Neutrogena

Pharmacologic Class
Retinoid.

Generic Name
Tretinoin

Available as
RETIN-A CREAM
(Tretinoin 0.025%, 0.05%, 0.1%)
RETIN-A GEL
(Tretinoin 0.01%, 0.025%; alcohol 90%)
RETIN-A LIQUID
(Tretinoin 0.05%; alcohol 55%)
RETIN-A MICRO
(Tretinoin [in microspheres] 0.04%, 0.1%; aqueous gel)

Indications
Acne vulgaris.

Adults
Initially apply sparingly to cleansed and completely dry skin once daily at bedtime. Adjust strength or frequency as tolerated and needed.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Not for use in eczema or on sunburned skin. Minimize exposure to sun,
UV light, and weather extremes. Avoid eyes, mouth, angles of nose, and mucous membranes. Pregnancy (Category C) Nursing mothers: Not recommended.

Interactions
Allow effects of benzoyl peroxide, sulfur, resorcinol, salicylic acid, other topical acne agents to subside before applying. Avoid keratolytics, abrasives, astringents, drying agents, high-alcohol content topical products, spices, lime.

Adverse Reactions
Transient symptom exacerbation or pigmentation changes, irritation, dryness, stinging, photosensitivity.

How Supplied Plenty of options Get the bigger tubes. Cause you'll use alot on your back. I use 20 grams per week. Plus it might help with strech marks.
Crm–20g, 45g
Gel–15g, 45g
Liq–28mL
Micro–20g, 45g
 
SALAC

SALAC

Company
Bioglan

Pharmacologic Class
Keratolytic.

Generic Name
Salicylic acid

Available as OTC
Salicylic acid 2%; medicated cleanser in surfactant base.

Indications
Acne.

Adults
Lather with warm water, massage into skin, rinse, and dry 2-3 times daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Avoid eyes.

Interactions
Excessive dryness or irritation with other topical agents.

Adverse Reactions
Excessive drying, allergic reactions.

How Supplied
Cleanser–6oz
 
SULFACET-R

SULFACET-R
Company
Dermik

Pharmacologic Class
Sulfonamide antibiotic + antibacterial/drying agent.

Generic Name
Sulfacetamide + Sulfur

Available as
Sodium sulfacetamide 10%, sulfur 5%; lotion; regular and tint-free.

Indications
Acne vulgaris, acne rosacea, seborrheic dermatitis.

Adults
Apply thin film and massage in 1-3 times daily.

Children
Not applicable.

Contraindications
Kidney disease. Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Discontinue if sensitization occurs. Avoid eyes, abraded or denuded skin. Pregnancy (Category C). Nursing mothers.

Adverse Reactions
Local irritation, allergic dermatitis; systemic toxic reactions in
sulfonamide-sensitive patients.

How Supplied
Lotion–25g
 
SUMYCIN

SUMYCIN
Company
Par

Pharmacologic Class
Tetracycline antibiotic

Generic Name
Tetracycline

Available as
SUMYCIN TABLETS
(Tetracycline HCl 250mg, 500mg)
SUMYCIN ORAL SUSPENSION
(Tetracycline 125mg/5mL; fruit flavor; contains sulfites)

Indications
Adjunct in severe acne.

Adults
Initially 1g daily in 2-4 divided doses.
After improvement: 125-500mg daily. Take with fluids.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Renal impairment. Asthma (susp). Monitor blood, renal and hepatic function in long-term use. Avoid sun and UV light. Pregnancy, Nursing mothers: Not recommended.

Interactions
Avoid methoxyflurane, photosensitizing agents. May antagonize bactericidal antibiotics. May increase serum digoxin levels. Reduced absorption with antacids, iron, zinc, calcium, magnesium, dairy products, urinary alkalinizers, other multivalent cations. May reduce effectiveness of oral contraceptives. Monitor prothrombin time with oral anticoagulants.

Adverse Reactions
Nausea, dizziness, rash, blood dyscrasias, pseudotumor cerebri, photosensitivity, increased BUN, hepatotoxicity.

How Supplied
Tabs: 250mg–100, 1000
500mg–100, 500
Susp–1 pt.
 
T-STAT

T-STAT
Company
Westwood Squibb

Pharmacologic Class
Macrolide antibiotic.

Generic Name
Erythromycin

Available as
Erythromycin 2%; soln; pads; alcohol 71.2%.

Indications
Acne vulgaris.

Adults
Apply with applicator or pads to cleansed and dried area twice daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Avoid eyes, nose, mouth, and mucous membranes.
Pregnancy (Category C). Nursing mothers.

Interactions
Additive irritation with other topical agents (esp. abrasives or keratolytics).

Adverse Reactions
Superinfection, dryness, erythema, pruritus, burning sensation.

How Supplied
Soln (applicator optional)–60mL
Pads–60
 
TAZORAC

TAZORAC

Company
Allergan Herbert

Pharmacologic Class
Retinoid.

Generic Name
Tazarotene

Available as
Tazarotene 0.05%, 0.1%; aqueous gel.

Indications
Mild-to-moderate facial acne vulgaris (0.1% strength only).

Adults
Cleanse and dry skin. Apply thin film of 0.1% to lesions on face once daily in the evening. Women of childbearing potential: begin therapy during normal menses.

Children
Not recommended.

Contraindications
Pregnancy (Category X). Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Obtain reliable negative pregnancy test within 2 weeks before starting therapy; use effective contraception during therapy.
Do not use on broken, eczematous, or sunburned skin.
Sun sensitivity. Avoid sun and UV light; use adequate sun protection. Increased irritation in extreme weather (eg, wind, cold). Discontinue if excessive irritation occurs. Nursing mothers.

Interactions
Avoid use until the effects of strong topical drying agents have subsided. Caution with other photosensitizers (eg, tetracyclines) or irritants (eg, topical astringents, abrasives, depilatories, permanent wave solutions, products with high alcohol concentration).

Adverse Reactions
Desquamation, burning/stinging, dry skin, erythema, pruritus, other local reactions.

How Supplied Try and get the 100gram tube.
Gel–30g, 100g
 
TETRACYCLINE

TETRACYCLINE

Company
Various

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Tetracycline

Available as
TETRACYCLINE (Tetracycline HCl 250mg, 500mg; capsules, tablets)
TETRACYCLINE SUSPENSION
(Tetracycline 125mg/5ml; flavored oral suspension)

Indications
Adjunct in severe acne.

Adults
Initially 1g daily in 2-4 divided doses.
After improvement: 125-500mg daily. Take with fluids.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Renal impairment. Asthma (suspension). Monitor blood, renal
and hepatic function in long term use. Avoid sun and UV light.
Pregnancy, Nursing mothers: Not recommended.

Interactions
Avoid methoxyflurane, photosensitizing agents.
May antagonize bactericidal antibiotics.
May increase serum digoxin levels.
Reduced absorption with antacids, iron, zinc, calcium, magnesium,
dairy products, urinary alkalinizers, other multivalent cations.
May reduce effectiveness of oral contraceptives.
Monitor prothrombin time with oral anticoagulants.

Adverse Reactions
Nausea, dizziness, rash, blood dyscrasias, superinfection, pseudotumor cerebri, photosensitivity, increased BUN, hepatotoxicity.

How Supplied
Caps: 250mg–60, 100, 500, 1000
500mg–50, 100, 500, 1000
Tabs: 250mg–30, 60
500mg–30, 60
Susp–60ml, pint
 
VIBRAMYCIN

VIBRAMYCIN

Company
Pfizer

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Doxycycline

Available as
VIBRAMYCIN CAPSULES
(Doxycycline [as hyclate] 50mg, 100mg)
VIBRAMYCIN SYRUP
(Doxycycline [as calcium] 50mg/5mL; raspberry-apple flavor; contains sulfites)
VIBRAMYCIN SUSPENSION
(Doxycycline 25mg/5mL; raspberry flavor)
VIBRA-TABS
(Doxycycline [as hyclate] 100mg; tablets)

Indications
Adjunct in severe acne.

Adults
100mg every 12 hours for one day, then 100mg daily in 1-2 divided doses. Reduce dose after improvement. Take with fluid.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Monitor blood, renal and hepatic function in long-term use. Avoid sun and UV light. Asthma (syrup). Pregnancy (Category D), Nursing mothers: Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption. Avoid concomitant penicillins, methoxyflurane. Carbamazepine, hydantoins may decrease effectiveness. Monitor prothrombin time with oral anticoagulants. Oral contraceptives may be less effective.

Adverse Reactions
Photosensitivity, GI upset, rash, blood dyscrasias, hepatotoxicity.

How Supplied
Caps: 50mg–50
100mg–50, 500
Syrup–1oz, 16oz.
Susp–2oz
Tabs–50, 500
 
As you can tell their are many choices of MED RX drugs. Please note that they come in various dosages in various methods. You can get gel, cream, lotion, wash, bar, pads, applicators, pills, tabs caps, oral suspension, chew tabs, and syrup. Just look over all the info and when you see the doctor just say I did some research and think that this @#$% drug in this dosages will work. Don't let him give you a small ass tube because if its your back/shoulder area remember that your not a 120lb teen.

What works on your faces my or may not work for your back ETC. I tazorac on my face and retin-a on my back. But will try tazorac all over. Then the last step will be accutane if needed.

KARMA KARMA KARMA:D :fro:
 
My Acne Tricks

I still don't buy the medical community's assessment that diet does not affect acne. I have tried most acne medications (differin, antibiotics, accutane, etc.), with only moderate success -- the exception being accutane, but the side-effects were too great. Since then I decided to see if the old wive's tale about candy and pizza giving you acne was true. So I systematically removed sugars and dairy products from my diet. Surprisingly, the cystic acne that I had on my face and back subsided considerably. I only got tiny little blemishes. So if you have bad cystic acne, try cutting out dairy, but you can still use whey supplements.

Also, i heard that sugar had good anti-inflamation properties. So whenever I wash my face, I pour a little bit of sugar onto the lathered cleanser and allow it to disolve. I then wash my face like I normally do. This definitely lessens the redness of acne. I strongly recommend anyone with facial acne give this a try for one week -- I guarantee that you'll see a difference!
 
Damn bro! :eek2: I realize you didn't type out the entire thread but that's still a ton of work.

Karma 4 U.
 
trial0r said:
cool post, too bad nothing short of the hand of god will clear my shit up.

I feel you. But with all those different drugs you have to be able to CONTROL the acne. It will take some time and trial but you find what works for you. Remember most acne meds take over4 weeksbefore they even start to help.
 
Great job bro. Thats alot of work you put into this and i know you did it to increase the value in this board. You got karma from me and a nomination for this post to be either a "STICKY" or in the "BEST OF ELITE" forum.
 
Thanks. I just know that from other post poll on side effect that ACNE was number one problem. Its just a fucking pimple so thiers has to be a way we (meatheads) can pick out the best meds to control it. Our acne comes from extra hormone induced. So far I used some oral meds and no help. Tried some topicals and they help to control. Tazorac so far is working to the point of almost clear skin. I like retin-a gel at low dose because I can still tan.
I would hope that board members would post thier results when trying out the meds. The better educated we are the better bodies we'll have.
 
I said fuck it last week and started accutane. At least I tried most everthing else. This is the cure not temp solution to the problem.

Dry them oil glands UP!
 
ryker77 said:

Have you tried that Retin-A micro bead facewash?

Saw it advertised recently on TV, and it looks OK.

Prescription only though.

Personally, I just use Tea Tree oil Facewash and a medicated
scrub.

Fonz
 
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