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Accurate practical encapsulation of steroid powders

B182

New member
When ordering bulk powders for oral administration it's usually left up to the user to use one of two options to utilize the product in an accurate dose measured manner. One is disolving in an alcoholic solution like bacardi rum or 151, but there is an inconvenience factor involved with having to tote a bottle of drops with you. The second method provides a more convenient final product, but the process of producing it is costly and time consuming- weighing through expensive electronic microscales, and individual distribution of the appropriate amount in each capsule.

With that being said, I thought of an alternative method that combines a little of the two...

Supplies needed:

-99% isopropyl/ethanol/methanol alcohol (they MUST be at least 99% pure- while two of these are highly toxic for ingestion, it's of no concern as you wont be consuming them)

-Larger volume syringe w/ large needle (18ga would be great)

-00 gelatin capsules

-Cap em Quick encapsulator

-container in which the oral powder is dissolved with the alcohol.

Dissolve the compound in the 99% isopropyl alcohol with a ratio of each compound that produces the equivilant of one desired dose per mililitre. Once dissolved, draw up the solution into the syringe, and distribute 1ml of the alc. into each one of the empty 00 capsule halves held upright by the Cap Em Quick capper. The alcohol must be of high purity because any water content would slow the evaporation process as well as cause the gelatin capsule to decompose. Once all the capsule halves have been filled, set it aside and allow the alcohol to evaporate overnight. 24hrs later, you should find each capsule with a crystaline residue lining each capsule half- then simply put the top caps on and you have the finished product, in an accurately dosed, convenient, and affordable manner.
 
You can't really easily get ethanol in anything over 180 proof, because distilling it beyond that point requires a very expensive process. Otherwise, swell.
 
That's true, denatured high purity ethanol is readily available through chem. supply companies, but isopropyl or methanol would probably be cheaper.
 
humm, disolve the powder in poison (2 out of 3), then let the poison evaporate.... not what I would do :)

Are there gel caps that everclear or bacardi won't dissolve?
What about suspending it in an oil solution (like vitamin e gelcaps, etc.)?
 
The problem with bacardi and other liquers is that they contain water- as already above, any water content will cause the gelatin capsule to decompose and you will end up with a mess of gunk. Oil would work for the very short term, however it will leak out from the capsules causing a mess if not used within a matter of hours.

The fact that methanol and isopropyl are of high toxicity is irrelevant provided you can be patient enough to allow the alcohol to evaporate completely.
 
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Can the gel caps withstand alcohol? Don't they dissolve? Why not using acetone instead of alcohol, much more volatile, readily available and low toxicity (in trace amounts). And what is wrong with mixing your favorite powder with a filler, like starch?
 
The problem with using the filler method is that with highly dose sensitive substances (like steroids), it's not practically feasible for the do-it-yourselfer to achieve an acceptably homogenous mixture, added to the fact the inconsistencies in pressure, and packing can affect how much total powder is placed in each cap and are largely beyond control of the maker.
 
fillers work

Actually, the filler method works better than you think. You can achieve less than a +/- 5% variation. (validated using lab tests). I've seen numbers on nominal 25 mg. capsules of 24.6, 24.8, 25.2.
 
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