? About ALA (alpha lipoic acid)

[TommyGunns]

My understanding is that ALA stimulates insulin receptors on muscle cells which increases uptake of glucose, i.e. disposing glucose into the muscle cell.

The question I have is does ALA also increase insulin activity at fat cells? If it did, could it have somewhat negative effects (if above maintenance calories) in that it would tend
to promote fat gain? Also, if ALA does increase insulin activity at the fat cells, is activity preferentially at the
muscle cell over the fat cell?

As far as dieting is concerned, ALA would seem to offer great benefits if on a low carb CKD.

 

[Ulter]

ALA doesn't lower your plasma insulin levels only r-ALA will do that. Some of you understanding is off a little but end result is the same. If you use r-ALA your carbs will be disposed of into the muscle cells.

 

[TommyGunns]

Uter,

So basically, if I add ALA to a meal I will have diverted more glucose/nutrients into my muscle cells than into my fat cells?

Just trying to figure this out Uter.

 

[macrophage69alpha]

Uter,

So basically, if I add ALA to a meal I will have diverted more glucose/nutrients into my muscle cells than into my fat cells?

Just trying to figure this out Uter.

this really depends...

with racemic ala.. its kind of unclear and it seems to depend on how many calories.. ie.. if really bulking this seems to greatly enhance fatty deposition. though perhaps at higher doses (3g+ this may be less true..) .. however there is the strange belly distension (almost certainly an insulin issue) that accompanies the use of racemic ala (at least for some)

with r-ala.. there is a decrease in plasma insulin.. this decreases adiposity.. both from carbs and fats.. only a minimal amount of insulin is needed for anabolism... with r-ala there should be less fat gain when bulking and more carbs shuttled to muscle than with regular ala (at least in theory)..

the difference between the 2 is more noticeable by older people and people that are insulin insensitive (who produce more insulin than necessary in most cases already..)



as far as you CKD question..

the use of r-ala should make this an obsolete question.. the whole point of CKD is to lower insulin)

high doses of ala may be better suited for use with CKD (may.. at least from anecdotals.. at least from cost perspective)..

 

[Norway]

Can i buy R-ALA from http://www.yohimburn.com/yoeu.htm

????

 

[macrophage69alpha]

http://www.yohimburn.com/Merchant2/merchant.mv?Screen=PROD&Store_Code=Y&Product_Code=EURALA

 

[TommyGunns]

Thanks for your replies.