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AAS and Immune System...

yea, they make you invincible like in video games man!
haha fuck wtf kind of idiots are on these chat rooms man
shootfighter im gonna slap you if you ever post again biitch
 
cokesniff said:
yea, they make you invincible like in video games man!
haha fuck wtf kind of idiots are on these chat rooms man
shootfighter im gonna slap you if you ever post again biitch
who the fuck are you COCKSNIFF? HE WAS JUST ASKING? CHILL BRO :)
 
cokesniff said:
yea, they make you invincible like in video games man!
haha fuck wtf kind of idiots are on these chat rooms man
shootfighter im gonna slap you if you ever post again biitch

Ive seen alot worse questions on here.
 
no need to cry shootfighter...go play on the playground its recess time
 
I know the body of evidence out there says that AAS lower the imune system, but I hardly ever get sick when Im on cycle. It seems like to me that my immune system is stronger than normal when on, but once I go off into PCT it all goes to hell. In the past when I didnt do proper PCT I would get sick alot during that time.
 
Keep talking cokesniff!

Every word you type makes you look like an even bigger clown..... Good job.

Thanks to the other guys for your helpful replies.....
 
I ran a quick pubmed search and there was not a ton of compelling evidence that AAS impairs immune function. There were some animal studies and other interesting studies in other, non-human models, that suggest that certain effector cells (T-lymphocytes and macrophages) can be impaired in these models but I did not see any solid evidence looking at large human populations.

You would imagine that if there was a drastic reduction in immune function, that all of the AIDS pts on AAS treatment would be dropping like flies from opportunistic infections such as CMV reactivation, PCP pneamonia, fungal infections etc. I did not see any evidence of this from my cursory search.

I also think that AAS may get lumped in with the well-known immune suppressive properties of corticosteroids.

If any-1 has data to the contrary, Id like to see it.

Oh, and ass[coke]-sniff, please put the coke down and step away from the table ya fruit!
 
From my understanding nandrolone boosts T cell count. A decrease in estrogen such as is the case with a cycle consisting of non-aromatizing compunds will impair the immune system to a degree.
 
The following 3 (OLD) studies indicated a potential benefit to immne function, but were in small populations and have not been validated.-

Schlumpberger JM, et al, "CD8+ lymphocyte counts and the risk of death in advanced HIV infection" J of Family Practice 1994;38,1(Jan):33-38.

Ooshika, N., et al, "Effect of an anabolic steroid on cellular immunity and postoperative evaluation of uterine cervical cancer" Japanese J of Cancer and Chemotherapy 1984;11(10):2177-2184

Huys JV et al, "Effect of nandrolone decanoate on t-cell lymphocytes during radiotherapy." Clin Therapeutics 1979; 2 (5) :352-357)

______________________________________________________________________
While these 2 studies looked at a randomized cohort of 75 HIV patients and ~35 patients. Both studies demonstrated no direct immune benefit as measured by CD4 lymphocyte counts, and do NOT validate results from the first 3.

A prospective study on the safety and effect of nandrolone decanoate in HIV-positive patients.
Int Conf AIDS 1996 Jul 7-12; 11:26 (abstract no. Mo.B.423)
Bucher G, Berger DS, Fields-Gardner C, Jones R, Reiter WM; Center for Special Immunology, Chicago, IL, USA. Fax: 312-296-1097.

Effects of Pharmacological Doses of Nandrolone Decanoate and Progressive Resistance Training in Immunodeficient Patients Infected with Human Immunodeficiency Virus
The Journal of Clinical Endocrinology & Metabolism Vol. 84, No. 4 1268-1276

It seems like the jury is still out on this question.
 
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