Very bloody soon imo.
THey key is that we humans are not really very good with coming up with new things and we are much much better at adapting things to novel solutions.
Life extension actually appears to be by most-all acoounts to be a lot simplier that we thought in the past. Telomeres...
GHB is accepted to give a 9fold increase in Prolactin levels and 16fold Gh release based greatly on a Japanese Study. (Search google for GHB GH PROLACTIN).
The primary Prolactin path can be balanced against Dopamine.
Certain commonly available fresh Beans (food grade.. esp the Pod) are...