Re: To Pat- Does this help any?
Posted by PA on March 20, 1997 at 14:18:26:
In Reply to: Re: To Pat- Does this help any? posted by Another Jeff on March 20, 1997 at 13:08:15:
: Hey Pat,
: Me telling you something is like me telling Noah all
: about how floods are (in other words you probably
: already know all this) but here goes.
: From an examination of the hypothalamus/testicular
: axis, an increase in spermatogenesis would very
: probably also involve an increase in testosterone.
: I could write a book, but here is the brief, condensed
: 1. The hypothalamus releases GnRH
: 2. The GnRH stmulates FSH and LH
: 3. FSH increase = increase in androgen binding proteins (ABP)
: 4. LH acts on the interstitial cells to increase testosterone
: 5. The interaction of the ABP and the testosterone within the
: seminiferous tubule is what causes spermatogenesis.
: As you can see, an increase in spermatogenesis has
: to come from an increase in GnRH to result in an
: increase in the two main ingredients necessary- ABP
: and testosterone.
: Having said all that, "Bone" and I are in the process
: of testing all of this out which will also include
: a look into the botanical abstracts to review the
: actual studies on tribulis. I will be happy to post
: our findings. Hope that helped? Thanks for your
: comment about not immediately believing supplement
: claims. You are very correct about that.
: Another Jeff
Dude I am sure there are many other steps that can be effected
that are independent or succeeding the androgen increase. Did you know that
pregenolone has been shown to increase spermatogenesis? Do you honestly
think that it is via increased gonadotropin secretion/androgen production?
Perhaps yes if you are talking about an autocrine process but that would have no
effect on systemic androgen levels and subsequent muscle growth.