hog426 said:
Does anyone have any input on this. trying to get cut for a show in August and would like to see some opinions on these two compounds.
I've personally been using albuterol and having nothing but positive results with no sides. I've haven't had to take any supplementation as I did with clen. Although, I received great results from using both products Here is something I found posted on another board.
Albuterol, like its closely related chemical cousin clenbuterol, is an asthma medication that has been adopted by athletes and bodybuilders as an ergogenic aid. Like clenbuterol, albuterol binds to the so called beta 2 adrenergic receptors found on cells throughout the body. The beta 2 receptors on fat cells activate an enzyme called hormone sensitive lipase.
This breaks up stored fat into free fatty acids that are able to then leave the fat cell and serve as a fuel source in other tissues. In athletes the primary target of these fatty acids is working muscle. This is the familiar process we know as lipolysis. Albuterol, like clen, is a potent lipolytic agent. But simply freeing up fat is not enough. Unless the body can burn the extra FFA they will simply be reincorporated into fat. Albuterol has the ability to elevate a person's metabolic rate so these FFA can be utilized for fuel.
Numerous animal studies have shown that clenbuterol increases both muscle size and strength; data supporting these effects in humans are sparse.
Albuterol on the the other hand has been shown to significantly increase both strength and endurance in humans (1,2). As an added benfit, albuterol lowers LDL and total cholesterol, while at the same time elevating HDL, the "good cholesterol":
"Significant alterations (P < or = .02) were observed in total cholesterol ([TC] -9.1% +/- 2.5%), low-density lipoprotein cholesterol ([LDL-C] - 15.0%
+/- 2.9%), and high-density lipoprotein cholesterol ([HDL-C] +10.4% +/-
3.2%) concentrations, as well as the TC/HDL-C (-17.4% +/- 2.6%) and LDL-C/HDL-C (-22.9% +/- 2.4%) ratios." (3)
4 mg of albuterol taken approximately 1 to 2 hours before a workout allows for peak plasma levels to be reached during the training session.
Additionally the much shorter half life of albuterol compared to clenbuterol allows one to benefit from its ergogenic effects during a training session but not suffer the sleeplessness that many clenbuterol users experience. Moreover, the short half life leads to much less beta 2 receptor downregulation than with clenbuterol, allowing one to use the drug daily for longer periods of time. On the other hand, if one is primarily interested in fat loss rather than performance enhancement, one could take
3 or 4 multiple doses of albuterol throughout the day, always of course cutting back if clenbuterol-like side effects are felt.
Albuterol, like its closely related chemical cousin clenbuterol, is an asthma medication that has been adopted by athletes and bodybuilders as an ergogenic aid. Like clenbuterol, albuterol binds to the so called beta 2 adrenergic receptors found on cells throughout the body. The beta 2 receptors on fat cells activate an enzyme called hormone sensitive lipase.
This breaks up stored fat into free fatty acids that are able to then leave the fat cell and serve as a fuel source in other tissues. In athletes the primary target of these fatty acids is working muscle. This is the familiar process we know as lipolysis. Albuterol, like clen, is a potent lipolytic agent. But simply freeing up fat is not enough. Unless the body can burn the extra FFA they will simply be reincorporated into fat. Albuterol has the ability to elevate a person's metabolic rate so these FFA can be utilized for fuel.
Numerous animal studies have shown that clenbuterol increases both muscle size and strength; data supporting these effects in humans are sparse.
Albuterol on the the other hand has been shown to significantly increase both strength and endurance in humans (1,2). As an added benfit, albuterol lowers LDL and total cholesterol, while at the same time elevating HDL, the "good cholesterol":
"Significant alterations (P < or = .02) were observed in total cholesterol ([TC] -9.1% +/- 2.5%), low-density lipoprotein cholesterol ([LDL-C] - 15.0%
+/- 2.9%), and high-density lipoprotein cholesterol ([HDL-C] +10.4% +/-
3.2%) concentrations, as well as the TC/HDL-C (-17.4% +/- 2.6%) and LDL-C/HDL-C (-22.9% +/- 2.4%) ratios." (3)
4 mg of albuterol taken approximately 1 to 2 hours before a workout allows for peak plasma levels to be reached during the training session.
Additionally the much shorter half life of albuterol compared to clenbuterol allows one to benefit from its ergogenic effects during a training session but not suffer the sleeplessness that many clenbuterol users experience. Moreover, the short half life leads to much less beta 2 receptor downregulation than with clenbuterol, allowing one to use the drug daily for longer periods of time. On the other hand, if one is primarily interested in fat loss rather than performance enhancement, one could take
3 or 4 multiple doses of albuterol throughout the day, always of course cutting back if clenbuterol-like side effects are felt.
(1) Med Sci Sports Exerc. 2000 Jul;32(7):1300-6. Effect of salbutamol on muscle strength and endurance performance in nonasthmatic men. van Baak MA, Mayer LH, Kempinski RE, Hartgens F.
(2) Aviat Space Environ Med. 2004 Jun;75(6):505-11 Albuterol helps resistance exercise attenuate unloading-induced knee extensor losses.
Caruso JF, Hamill JL, Yamauchi M, Mercado DR, Cook TD, Keller CP, Montgomery AG, Elias J.
(3) Metabolism. 1996 Jun;45(6):712-7 Effects of oral albuterol on serum lipids and carbohydrate metabolism in healthy men. Maki KC, Skorodin MS, Jessen JH, Laghi F.
more,
Albuterol does not effect VO2 max and improves strength
Med Sci Sports Exerc. 2000 Jul;32(7):1300-6. Related Articles, Links Click here to read Effect of salbutamol on muscle strength and endurance performance in nonasthmatic men.
van Baak MA, Mayer LH, Kempinski RE, Hartgens F.
Department of Human Biology, Maastricht University, The Netherlands.
PURPOSE: The ergogenic effect of acute beta2-adrenergic agonist administration in nonasthmatic individuals has not been clearly demonstrated. Therefore, the acute effects of oral administration of the beta2-adrenergic agonist salbutamol (4 mg) on muscle strength and endurance performance were studied in 16 nonasthmatic men in a double-blind randomized cross-over study. METHODS: Peak expiratory flow (Mini Wright Peakflowmeter), isokinetic strength of the knee extensors and knee flexors at four angular velocities (Cybex II dynamometer), and endurance performance in a cycle ergometer test until exhaustion at 70% of maximal workload were measured. RESULTs: Peak expiratory flow increased from 601
+/- 67 L x min(-1) to 629 +/- 64 L x min(-1) after salbutamol (P < 0.05).
Peak torque was higher after salbutamol than after placebo (4.4% for the knee extensors, 4.9% for the knee flexors) (P < 0.05). Mean endurance time increased from 3,039 +/- 1,031 s after placebo to 3,439 +/- 1,287 s after salbutamol (P = 0.19). When four subjects complaining about adverse side effects were excluded from the analysis, the increase in endurance time
(729 +/- 1,007 s or 29%) was statistically significant (P <-0.05).
Salbutamol did not affect VO2, respiratory exchange ratio, heart rate, and plasma free fatty acid and glycerol concentration during exercise; plasma lactate and potassium concentrations were increased (P < 0.05).
CONCLUSIONS: Under the conditions of this study, oral salbutamol appears to be an effective ergogenic aid in nonasthmatic individuals not experiencing adverse side effects.