As athletes, we are most concerned with the "PT" part of the hpta - hypothalamic-pituitary-testicular axis - . "P" being the pituitary and "T" being the Testes. To review, our hormonal responses are based mainly on negative feedback. For example, supragenetic levels of testosterone
or any anabolic steroids will signal the pituitary to stop secreting lh - leutenizing hormone - and will signal the hypothalamus to stop secreting gonadotropin-releasing hormone (GRH). So, during an anabolic steroids cycle
, we experience low, natural Testos levels, a reduction in testuclar mass, low lh - leutenizing hormone - , and low GRH. The goal of PCT - post cycle therapy - (recovery) is to get the hpta - hypothalamic-pituitary-testicular axis - back to normal.
The most important aspect of recovery is getting testicular mass back to normal as quickly as possible. There is only one drug that will do this and do it quickly--HCG - human chorionic gonadotropin - . HCG - human chorionic gonadotropin - imitates lh - leutenizing hormone - (which is suppressed). HCG - human chorionic gonadotropin - acts independently of the hpta - hypothalamic-pituitary-testicular axis - suppression and independent of the meds from the anabolic steroids cycle
. In this situation, the only side effect we need to worry about is the return of estrogen to normal levels (estrogen rebound). Since estrogen is already at very low levels (the athlete used an aromatase inhibitor during his anabolic steroids cycle
), Nolvadex is sufficient to block the onrush. By the time the athlete is using nolvadex-only, his testes are up to their normal size. And the pituitary begins to release its own lh - leutenizing hormone - .