! Test flu !

[Duramax747]

Im currently on a cycle going through what I believe is considered "Test Flu". I found this article on it and its actually exactly what I have especially the low fever sitting at 96.1 at the moment.

I just wanted to remind/educate anyone that does not know about this.

“Test Flu” – What it is and what to do

All of us at one time or another has experienced “Test Flu” in our cycles. I want to give some insight to educate the community and give some possible remedies in helping relieve the symptoms. So you can get the most out of your cycle.

First, what is “Test Flu”? It is not an official diagnosis that a physician would label, but a term that is associated with the flu because of the similarity of symptoms. The symptoms have a rapid onset. Often starts with the onset of low grade fever, headache, fatigue, and body aches. Not in that exact order or even all the symptoms listed may occur. Listed below are a few symptoms you may be experiencing:
• fever (low grade)
• severe aches and pains in the joints and muscles
• generalized weakness
• fatigue
• headache
• dry cough
• sore throat and watery discharge from your nose

“Test Flu” varies from individual to individual based on their immune system. It’s the intercorelation between your immune system and your endocrine. If you overload one then the other responds unfavorably. It’s your body’s auto immune response to the foreign substance that has entered your body and caused and influx of hormones. Your body sees the large increase as foreign and tries to get rid of it. Triggering an inflammatory response and raising you metabolism. Once your body builds its resistance to it, the symptoms relieve or even resolve. This usually takes a week or so.

“Test Flu” doesn’t necessarily mean your gear is dirty or that it’s good to go either. That’s more of an urban legend than truth.

Generally, the “Test Flu” is far more common with the short ester preparations like propionate. If you are using TestE then maybe consider to change to Test Cyp
A good rule of thumb is the shorter the carboxylic acid chain, then the greater degree of possible tissue irritation that can trigger the auto immune response. The reason being is these esters are acids, so they cause a localized reaction that the body reacts in a common defensive fashion and thus creating the “Test Flu”

Now this not always the case in every person because please remember we are all engineered differently. So everyone reacts differently to different things.

So what can we do to help to prevent or even reduce the symptoms in the meantime?
My OTC remedy is Vitamin C 4000mg in two split doses (2000mg in AM , 2000mg in PM) a day and Zinc 100mg in two split doses (50mg in AM, 50mg in PM) for a week and drop the dosages in half until symptoms subside. Drink plenty of water to ensure hydration which will also aid in recovery.

Ive took the 2000mg Vitamin C and it seems to be helping, Hope this helps broskies.

 

[eddymerckx]

stolen but easier than typing it out--test flu is a natural defense mechanism - to the sudden increase in exogenous hormone levels. Its the body's way of trying to "flush" out the foreign entity it perceives is there (just as it does w/ a flu virus). There has also been some connection between high BA content and immune response. think the combination of sudden increased hormone levels and a foreign substance being injected into the muscle can cause these symptoms. Some people are sensitive, some arent. Certain people don’t experience it at all and some might just get mild chills (low grade fever) or a runny nose for a few days and not even take much note of it.

etiocholanolone represents only about 20% of the metabolites of testosterone in people. Maybe folks who experience this reaction to testosteone have particularly high levels of 17 beta hydroxysteroid dehydrogenase, the enzyme that converts testosterone into etiocholanolone. Or an isoform of the enzyme that makes the conversion more efficient.

Etiocholanolone is believed to produce fever and flu-like aches and pains because it induces the systemic release of Interleukin-1, a powerful proinflammatory cytokine.

Etiocholanolone is the 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine and is androgenically inactive. Classified a ketosteroid, it causes fever (it is a pyrogen), immunostimulation and leukocytosis. The pyrogenic effect of Etiocholanolone has been shown to be due to the release of interleukin-1 (IL-1) from the leukocytes that are mobilized in response to its production or injection. Etiocholanolone has anticonvulsant activity and may be an endogenous modulator of seizure susceptibility. Significantly increased values of etiocholanolone (along with testoterone and androsterone) an be detected in the urine of men with androgenic alopecia (male pattern baldness).

see link below

HMDB: Showing metabocard for Etiocholanolone (HMDB00490)

 

[Duramax747]

stolen but easier than typing it out--test flu is a natural defense mechanism - to the sudden increase in exogenous hormone levels. Its the body's way of trying to "flush" out the foreign entity it perceives is there (just as it does w/ a flu virus). There has also been some connection between high BA content and immune response. think the combination of sudden increased hormone levels and a foreign substance being injected into the muscle can cause these symptoms. Some people are sensitive, some arent. Certain people don’t experience it at all and some might just get mild chills (low grade fever) or a runny nose for a few days and not even take much note of it.

etiocholanolone represents only about 20% of the metabolites of testosterone in people. Maybe folks who experience this reaction to testosteone have particularly high levels of 17 beta hydroxysteroid dehydrogenase, the enzyme that converts testosterone into etiocholanolone. Or an isoform of the enzyme that makes the conversion more efficient.

Etiocholanolone is believed to produce fever and flu-like aches and pains because it induces the systemic release of Interleukin-1, a powerful proinflammatory cytokine.

Etiocholanolone is the 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine and is androgenically inactive. Classified a ketosteroid, it causes fever (it is a pyrogen), immunostimulation and leukocytosis. The pyrogenic effect of Etiocholanolone has been shown to be due to the release of interleukin-1 (IL-1) from the leukocytes that are mobilized in response to its production or injection. Etiocholanolone has anticonvulsant activity and may be an endogenous modulator of seizure susceptibility. Significantly increased values of etiocholanolone (along with testoterone and androsterone) an be detected in the urine of men with androgenic alopecia (male pattern baldness).

see link below

HMDB: Showing metabocard for Etiocholanolone (HMDB00490)

Great read. Thanks for sharing.