Another use for tamoxifen?

[MS]

From an abstract presented by researchers at the Cardiff Breast Unit, Llandough Hospital, Penarth:

These folks speculated that women who underwnet breast removal surgery for breast cancer would have better healing scars if they were also taking tamoxifen as part of their therapy (tamoxifen is known to inhibit a growth factor that is involved in excess scar formation). As they suspected, women taking tamoxifen suffered much less scarring (8% 'unsatisfactory' scars) compared to women who were not taking tamoxifen at the time of surgery (25% 'unsatisfactory' scarring). The researchers conclude "Treatment with tamoxifen is associated with better looking operative scars. Our findings support the theory that tamoxifen should have a place in the treatment or prevention of hypertrophic scars."

Just thought you folks would like to know

 

[NubianBeauty]

I would rather use Oxandrolone

 

[The Ranger]

How bout Vit E...??? Out of curosity....or both??

Ranger

 

[MS]

How about all three??

Seriously though, oxandrolone may speed helaing, but I haven't come across anything that would make me think it will reduce scarring.

 

[MS]

Why don't we use vitamin E in dermatology?

Pehr K, Forsey RR.

Division of Dermatology, McGill University, Montreal, Que.

OBJECTIVE: To review the possible uses of topical and systemic tocopherols as therapy for skin conditions in light of the widespread
use of vitamin E by patients. DATA SOURCES: Index Medicus was searched for articles published from 1922 (when vitamin E was
discovered) to 1966 (the beginning of MEDLINE). MEDLINE was searched for articles in English and French on vitamin E or
tocopherol in relation to dermatology. Additional original articles were identified from the reference lists of the review articles. STUDY
SELECTION: Only well-designed controlled studies were accepted; anecdotes and open studies are cited for completeness and as
direction for future research. DATA SYNTHESIS: THERE WAS SOME WEAK OR CONFLICTING EVIDENCE that vitamin E is of value in yellow
nail syndrome, vibration disease, epidermolysis bullosa, cancer prevention, claudication, cutaneous ulcers, and COLLAGEN SYNTHESIS and
WOUND HEALING. It was of no use in atopic dermatitis, dermatitis herpetiformis, psoriasis, subcorneal pustular dermatosis, porphyrias and
skin damage induced by ultraviolet light. CONCLUSIONS: After 44 years of research there is still scant proof of vitamin E's
effectiveness in treating certain dermatologic conditions. Further research in well-designed controlled trials is needed to clarify vitamin
E's role.

 

[NubianBeauty]

How about all three??

Seriously though, oxandrolone may speed helaing, but I haven't come across anything that would make me think it will reduce scarring.

OK!

 

[wilson6]

"How about all three?? "

Just what I was thinking.

W6

 

[MS]

Here I was trying to offer some cheap, easily available options for minimizing post operative scarring, and you GUYS have to get all fancy, expensive and black market on me!!!!!

For the record, hGH (like oxandrolone) does not reduce the formation of scar tissue (at least not in burn victims). Sure, use oxandrolone or hGH to SPEED the healing of a wound, but throw in some tamoxifen to reduce the chances of those wounds scarring. A good rub with vitamin E won't hurt (and it's also cheap). Like W6 was thinking.