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- Thread starter Sebass67
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supersizeme
New member
yeah you got that off t-mag. Mag-10 is nothing revolutionary...it's still prohormones. i've read a few reviews from people who have taken it, and it doesn't have nearly the effect that they claim it does.
casavant
New member
supersizeme said:
Of course it doesn't- that's just marketing hype. And if they ever do come out with a pro-hormone whose potency approaches or surpasses that of anabolic steroids, how much do you really think it would differ in terms of side effects? And how long do you think it would stay legal? Not very much, and not very long.
T
The Shadow
Guest
WODIN - here's the 411
1-AD INFORMATION
What is it?
1-AD is the proprietary name for the prohormone 5alpha-androst-1-en-3,17-dione. 1-AD has the following properties:
· Orally active – greatly suppressed liver deactivation
· Converts directly and efficiently to a hormone over 700% more potent than testosterone
· Does not aromatize, nor do any of its metabolic products - absolutely no estrogen formation
· A naturally occurring endogenous hormone in man
Naturally occurring and proven to convert
1-AD has been shown to be present as a urinary androgen metabolite in both healthy and diseased men. This compound can interact in-vivo with the enzyme 17beta-hydroxysteroid dehydrogenase to form the active anabolic / androgenic hormone 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone). Evidence for this in-vivo conversion exists in the literature. 100mg of 1-AD given orally to men was found to result in considerable excretion of 1-testosterone in the urine.
Orally active
Androgenic steroids are normally not very active orally. Large amounts have to be taken orally to see biological effects. This is because the liver first pass causes a massive deactivation of the compounds, primarily through oxidation to17-keto steroids. Chemists long ago found that by adding an alkyl (methyl or ethyl) chemical group to the 17-carbon, this oxidation can be prevented. However, this alkyl derivatization also greatly increases the toxicity on the liver. Therefore the usage of such synthetically altered compounds (Methyl Testosterone, Anadrol, Winstrol) are not without substantial risk.
Luckily another structural modification was found to block the undesirable liver oxidative deactivation – and do so in a manner that does not lead to liver toxicity problems. Specifically, we are talking about the introduction of a double bond in the 1- position of the steroid molecule.
Most active steroids (4-androstenediol, testosterone, nandrolone) have bonds in the 4-position. If you take that double bond and "switch it" to the 1-position, then something very unique happens to the way your body metabolizes the steroid. The main route of deactivation, the 17beta-hydroxysteroid dehydrogenase (17beta-HSD) reaction, gets profoundly altered. The 17beta-HSD reaction is what is known as an equilibrium reaction (goes both ways), and for steroids with double bonds in the normal 4-position, this equilibrium reaction leans predominantly towards oxidative deactivation.
However, when the double bond is switched to the 1-position, the equilibrium is suddenly shifted in the other direction – towards activation of the steroid. What this means is that when you take 1-AD, a very large percentage of it will convert to "1-testosterone". Furthermore, the 1-tesosterone that is formed will be very stable, and will not quickly convert back to 1-AD.
The 1-position double bond was actually utilized in the design of Methenolone (Primobolan), which is well known by bodybuilders to be an orally active, liver safe anabolic steroid. Primobolan owes its oral activity in large part to the same structural characteristic that makes 1-AD orally active (compare the 1-AD structure to the Methenolone structure).
The amazing "1-testosterone"
All this comes together perfectly for us here. First we discover a new natural prohormone, 1-androstenedione. Secondly we discover that this prohormone is orally active. The third and fourth discoveries however, really make 1-AD shine superior.
1-AD does not convert to testosterone. Instead it converts to an isomer (a close chemical derivative) of testosterone. That isomer is known as 17beta-hydroxy-5alpha-androst-1-en-3-one, or "1-testosterone". Chemically speaking, it is simply an analog of testosterone that has the double bond in the 1-position instead of the 4-position. There are more than just chemical differences here though. 1-testosterone differs from regular testosterone, or "4-testosterone", in a couple of very amazing ways.
First of all, 1-testosterone’s anabolic activity is considerably greater than that of testosterone. In fact, it has been shown to be over 7 times as myotrophic (anabolic to muscle) than testosterone! That is not a typo - please check the reference if you do not believe me. Very, very few prescription anabolic agents even share such amazing power. I don’t think I have to say much more on this aspect.
No aromatization to estrogen
As if 1-testosterone being over 7 times as anabolic as testosterone was not enogh. 1-testosterone also DOES NOT AROMATIZE to estrogens. Being a 5alpha-reduced androgen (a DHT derivative) it simply cannot aromatize. The same goes for its precursor 1-AD; it too cannot aromatize to any extent whatsoever. This alone makes 1-AD superior to all other prohormones (diol or dione, nor or andro) because all other prohormones either aromatize themselves or convert to a hormone that aromatizes.
Bringing it all together
Lets put this all into perspective. When you take 1-AD orally, a high percentage of it gets past the liver. A high percentage of the 1-AD is then converted to its active hormone, 1-testosterone. This 1-testosterone is extremely potent and imparts strong anabolic effects on your muscle tissue. Furthermore, this 1-testosterone stays around for a while, and is not easily metabolized to inactive 17-keto steroids. And lastly, none of the 1-AD or 1-testosterone, or any other metabolic by product of the two can aromatize to estrogens.
After reading this, I don’t think you can argue that 1-AD is a huge cut above all the other prohormones that came before it. Even the prohormones that others have theorized about, but have yet to market, do not even come close to 1-AD. But what have I observed in the real world you may ask? I have found that 1-AD is extremely effective for strength gains, motivation in the gym, and muscle hardness. It is only moderately effective for weight gain however, and this is very likely due to the fact that water retention is minimal (no aromatization). Qualitatively speaking, its results are very similar to a strong androgen/anabolic like trenbolone.
I hope you found this interesting. Now that you know what 1-AD is and what it can do I hope that you will all give 1-AD a try.
ergopharm-1-ad-information
1-AD INFORMATION
What is it?
1-AD is the proprietary name for the prohormone 5alpha-androst-1-en-3,17-dione. 1-AD has the following properties:
· Orally active – greatly suppressed liver deactivation
· Converts directly and efficiently to a hormone over 700% more potent than testosterone
· Does not aromatize, nor do any of its metabolic products - absolutely no estrogen formation
· A naturally occurring endogenous hormone in man
Naturally occurring and proven to convert
1-AD has been shown to be present as a urinary androgen metabolite in both healthy and diseased men. This compound can interact in-vivo with the enzyme 17beta-hydroxysteroid dehydrogenase to form the active anabolic / androgenic hormone 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone). Evidence for this in-vivo conversion exists in the literature. 100mg of 1-AD given orally to men was found to result in considerable excretion of 1-testosterone in the urine.
Orally active
Androgenic steroids are normally not very active orally. Large amounts have to be taken orally to see biological effects. This is because the liver first pass causes a massive deactivation of the compounds, primarily through oxidation to17-keto steroids. Chemists long ago found that by adding an alkyl (methyl or ethyl) chemical group to the 17-carbon, this oxidation can be prevented. However, this alkyl derivatization also greatly increases the toxicity on the liver. Therefore the usage of such synthetically altered compounds (Methyl Testosterone, Anadrol, Winstrol) are not without substantial risk.
Luckily another structural modification was found to block the undesirable liver oxidative deactivation – and do so in a manner that does not lead to liver toxicity problems. Specifically, we are talking about the introduction of a double bond in the 1- position of the steroid molecule.
Most active steroids (4-androstenediol, testosterone, nandrolone) have bonds in the 4-position. If you take that double bond and "switch it" to the 1-position, then something very unique happens to the way your body metabolizes the steroid. The main route of deactivation, the 17beta-hydroxysteroid dehydrogenase (17beta-HSD) reaction, gets profoundly altered. The 17beta-HSD reaction is what is known as an equilibrium reaction (goes both ways), and for steroids with double bonds in the normal 4-position, this equilibrium reaction leans predominantly towards oxidative deactivation.
However, when the double bond is switched to the 1-position, the equilibrium is suddenly shifted in the other direction – towards activation of the steroid. What this means is that when you take 1-AD, a very large percentage of it will convert to "1-testosterone". Furthermore, the 1-tesosterone that is formed will be very stable, and will not quickly convert back to 1-AD.
The 1-position double bond was actually utilized in the design of Methenolone (Primobolan), which is well known by bodybuilders to be an orally active, liver safe anabolic steroid. Primobolan owes its oral activity in large part to the same structural characteristic that makes 1-AD orally active (compare the 1-AD structure to the Methenolone structure).
The amazing "1-testosterone"
All this comes together perfectly for us here. First we discover a new natural prohormone, 1-androstenedione. Secondly we discover that this prohormone is orally active. The third and fourth discoveries however, really make 1-AD shine superior.
1-AD does not convert to testosterone. Instead it converts to an isomer (a close chemical derivative) of testosterone. That isomer is known as 17beta-hydroxy-5alpha-androst-1-en-3-one, or "1-testosterone". Chemically speaking, it is simply an analog of testosterone that has the double bond in the 1-position instead of the 4-position. There are more than just chemical differences here though. 1-testosterone differs from regular testosterone, or "4-testosterone", in a couple of very amazing ways.
First of all, 1-testosterone’s anabolic activity is considerably greater than that of testosterone. In fact, it has been shown to be over 7 times as myotrophic (anabolic to muscle) than testosterone! That is not a typo - please check the reference if you do not believe me. Very, very few prescription anabolic agents even share such amazing power. I don’t think I have to say much more on this aspect.
No aromatization to estrogen
As if 1-testosterone being over 7 times as anabolic as testosterone was not enogh. 1-testosterone also DOES NOT AROMATIZE to estrogens. Being a 5alpha-reduced androgen (a DHT derivative) it simply cannot aromatize. The same goes for its precursor 1-AD; it too cannot aromatize to any extent whatsoever. This alone makes 1-AD superior to all other prohormones (diol or dione, nor or andro) because all other prohormones either aromatize themselves or convert to a hormone that aromatizes.
Bringing it all together
Lets put this all into perspective. When you take 1-AD orally, a high percentage of it gets past the liver. A high percentage of the 1-AD is then converted to its active hormone, 1-testosterone. This 1-testosterone is extremely potent and imparts strong anabolic effects on your muscle tissue. Furthermore, this 1-testosterone stays around for a while, and is not easily metabolized to inactive 17-keto steroids. And lastly, none of the 1-AD or 1-testosterone, or any other metabolic by product of the two can aromatize to estrogens.
After reading this, I don’t think you can argue that 1-AD is a huge cut above all the other prohormones that came before it. Even the prohormones that others have theorized about, but have yet to market, do not even come close to 1-AD. But what have I observed in the real world you may ask? I have found that 1-AD is extremely effective for strength gains, motivation in the gym, and muscle hardness. It is only moderately effective for weight gain however, and this is very likely due to the fact that water retention is minimal (no aromatization). Qualitatively speaking, its results are very similar to a strong androgen/anabolic like trenbolone.
I hope you found this interesting. Now that you know what 1-AD is and what it can do I hope that you will all give 1-AD a try.
ergopharm-1-ad-information
We need a double blind study on effectiveness of Mag10 vs. (a form of gear). Something like Test, Deca or Dball and two candidates that are of about the same size.
Frorider and DOT
SSME and DOT
Frackal and DOT
SSME and Frackal.
Frorider and Warik
You know...lil bitches!
Frorider and DOT
SSME and DOT
Frackal and DOT
SSME and Frackal.
Frorider and Warik
You know...lil bitches!
FarBeyondDriven
New member
damn at the huge fuckers that are natural, I knew I was headed the wrong way with that needle and vial.
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