There have been studies showing that it may act as an appetite depressant. In the past, I have used it while following low calorie diets and CKD's for this purpose and it seemed to be fairly effective....with no problems.
What about saccharine and cyclamates ?
They have been suspected to be carcinogenic (though they have been "cleared" by the fda and declared GRAS - Generaly recognized as safe)
I agree Aspartame does kill the appetite. Someone told me once when i was really hungry and craving carbs to just take a small packet of Aspartame and eat it, it actually worked pretty good i can say. Killed desire for carbs and helped kill appetite a bit. I know also after a shake w/ aspartame i wont feel hungry for a while and have to force my 2nd shake in.