Plornive, I don’t pretend to know THE answers to your questions, but I’ll give you my opinion for all to flame or discuss. “Do you think that protein assimilation is unaffected by protein intake frequency?”
Without a doubt you can absorb more than 30g protein in one meal. If you read the first abstract I mentioned (
http://www.ncbi.nlm.nih.gov:80/entr...ve&db=PubMed&list_uids=10867039&dopt=Abstract) you'll see that they gave the women a 2 week "adaptive" protein diet to get their body's accustomed to higher protein intake before they fed the experimental protein diet. This is in contrast to earlier studies (where they grabbed some young guys off the street and shoved gobs of protein down their gullet without allowing their system to adapt). In any event, it prolly doesn’t matter so much for BB cutting diets since these tend to be grossly over supplied with protein anyway, and if some digestion/absorption is reduced it merely means less calorie intake than calculated, therefore a greater rate of weight loss.
“Also, do you think that fat-loss vs. muscle loss is the same regardless of meal frequency?” I dunno to be honest.
“It seems like keeping blood sugar at a constant would allow the body to constantly be in a more ideal state”. Not necessarily. Remember that in normal, healthy folks with good insulin sensitivity that insulin is very anabolic. Dieting to lose fat (from a BB perspective anyway) needs to balance the anabolic properties of carb intake with the need to burn fat.
“It seems like there would be less gluconeogenesis, and less gluconeogenesis means less nitrogen loss, right”. Again not necessarily. The best inhibitor of gluconeogenesis is glucose! Glucose is also the best nitrogen sparing nutrient available. If you don’t provide your body with glucose from carbs and you’re not in ketosis, then your body will use dietary and/or skeletal protein for gluconeogenesis. This does not have to be a problem if you’re eating a very large amount of protein. But when calories are limited you are walking a fine line, and muscle catabolism is inevitable if you get lean enough.
“I also think workout performance is enhanced by frequent feedings and constant blood sugar.” This is 100% on the mark unless you are in established long term ketosis. This is the best reason to eat a balanced low GI meal pre workout. This is also why I think CKD sucks if you have a job where you need to use your brain.
“If you stopped eating at 6pm every day and didn't eat until morning, I think there would be catabolism. Eating only 3 meals per day while cutting seems similar to this.
Why look at nutrition in 24 hour periods instead of continuous time?……………………..”
I agree. The second question is what I think is the key question. So what if short term protein turnover is increased by infrequent feedings (which it’s not in young females)? You have to look at whole body metabolism over the long term. Keeping in mind that muscle catabolism is absolutely required for muscle remodelling and growth (unless you’re using AAS or happen to be Belgiun Blue double muscled cattle/calypige), you shouldn’t lose sleep over short term changes as long as it’s is working for ya over the long haul. We all know that the stress of worrying about your diet is catabolic LOL. In other words, there may be catabolism from 6pm until the morning meal, but this will almost always be followed by anabolism provided protein intake is adequate and the training stimulus is intense enough. Our paleolithic ancestors would have never grown to adulthood if this weren’t true. They surely didn’t eat 6 squares a day every day (well, OK I’m not 100% sure about that because none of us were there). We all still manage to “grow up” even with an overnight fast and only 2-3 meals per day (I’m talking about your average child raised on an average western diet here). I think it’s important on boards like this to distinguish between what works (or doesn’t work) in general, such as Terra Noble’s friend, versus what is cutting edge for BB’s that have exhausted all of their natural training and diet avenues and are looking for that 1% advantage. I will venture to say that there are very few BB’s on this diet board that have given good training, diet and rest a fair trial over enough years to be worried about the details we’re discussing here.