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Glutamine: The ESSENTIAL amino acid...


Welcome to the EliteFitness.com Bodybuilding Site! Please join this discussion about Glutamine: The ESSENTIAL amino acid... within the Bodybuilding Supplements category.

Excerpt: Glutamine is a very underestimated weapon in the bodybuilding repertoire.Even while in an enhanced A/S state of metabolic favoribility,IMMUNE SYSTEM response and reaction to the trauma we are inflicting upon ourselves in the gym is an often overlooked impediment in our road to physical self-greatness.Glutamine is a multi-functional ergonic aid.It not only greatly improves immune response/recovery reaction to trauma,but it improves liver function and serves as a very potent cell

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  1. #1
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    Glutamine: The ESSENTIAL amino acid...

    Glutamine is a very underestimated weapon in the bodybuilding repertoire.Even while in an enhanced A/S state of metabolic favoribility,IMMUNE SYSTEM response and reaction to the trauma we are inflicting upon ourselves in the gym is an often overlooked impediment in our road to physical self-greatness.Glutamine is a multi-functional ergonic aid.It not only greatly improves immune response/recovery reaction to trauma,but it improves liver function and serves as a very potent cell volumizer,perhaps second only to creatine monohydrate in this regard as a non-drug osmotic enhancer.The following is an abstract which goes into further detail of this tremendous augmentory amino acid.It would be a wise idea to include it in your future bodybuilding arsenal if not already doing so.---Huck

    Glutamine: effects on the immune system, protein balance and intestinal functions]
    Roth E, Spittler A, Oehler R
    Wien Klin Wochenschr 1996 108:669-76

    Abstract
    Glutamine is the most abundant free amino acid of the human body. In catabolic stress situations such as after operations, trauma and during sepsis the enhanced transport of glutamine to splanchnic organs and to blood cells results in an intracellular depletion of glutamine in skeletal muscle. Glutamine is an important metabolic substrate for cells cultivated under in vitro conditions and is a precursor for purines, pyrimidines and phospholipids. Increasing evidence suggests that glutamine is a crucial substrate for immunocompetent cells. Glutamine depletion in the cultivation medium decreases the mitogen-inducible proliferation of lymphocytes, possibly by arresting the cells in the G0-G1 phase of the cell cycle. Glutamine depletion in lymphocytes prevents the formation of signals necessary for late activation. In monocytes glutamine deprivation downregulates surface antigens responsible for antigen preservation and phagocytosis. Glutamine is a precursor for the synthesis of glutathionine and stimulates the formation of heat-shock proteins. Moreover, there are suggestions that glutamine plays a crucial role in osmotic regulation of cell volume and causes phosphorylation of proteins, both of which may stimulate intracellular protein synthesis. Experimental studies revealed that glutamine deficiency causes a necrotising enterocolitis and increases the mortality of animals subjected to bacterial stress. First clinical studies have demonstrated a decrease in the incidence of infections and a shortening of the hospital stay in patients after bone marrow transplantation by supplementation with glutamine. In critically ill patients parenteral glutamine reduced nitrogen loss and caused a reduction of the mortality rate. In surgical patients glutamine evoked an improvement of several immunological parameters. Moreover, glutamine exerted a trophic effect on the intestinal mucosa, decreased the intestinal permeability and thus may prevent the translocation of bacteria. In conclusion, glutamine is an important metabolic substrate of rapidly proliferating cells, influences the cellular hydration state and has multiple effects on the immune system, on intestinal function and on protein metabolism. In several disease states glutamine may consequently, become an indispensable nutrient, which should be provided exogenously during artificial nutrition.

  2. #2
    Elite Mentor Big Buck's Avatar
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    already take it daily...good info though Huck.

  3. #3
    Good Bro
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    Great Info You the man Huck

  4. #4
    Olympian Big Brother Val's Avatar
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    Is there no end? Asses are bruised from another kick-ass post. And thanks again for your help, bigman.

  5. #5
    Pro Bodybuilder G-Force's Avatar
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    Thanks Huck - always appeciated!

  6. #6
    Mutant MaGilicuti's Avatar
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    Good info. Any info on dosages? Would there be a time to get off it such as with creatine? I used to take a teaspoon before I went to sleep.

  7. #7
    Pro Bodybuilder
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    Huck, I have read that the Uptake of Glutamine(like Creatine) is diminished when taken with Protein. When would be the best time to take it so that it does not have to compete with receptors?

  8. #8
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    Originally posted by MaGilicuti
    Good info. Any info on dosages? Would there be a time to get off it such as with creatine? I used to take a teaspoon before I went to sleep.
    Most essentail consumption time would be POST-WORKOUT with your protein shake.Take advantage of that window.Secondary would be right before bed,not only to influence GH secretion,but to aid as an anti-catabolic in your overnight fasting state.

  9. #9
    Good Broly
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    Good post Huck I knew I should bust out that Glut jar in the back of the cubard!

  10. #10
    Freak Thaibox's Avatar
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    Good info Huck

    I take 20g post workout and 20g right before bed. But its getting expensive. Anybody know where to get a decent deal on a high quality industrial sized tub?

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