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Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

Alanine

Sorry !
the vitamin C thread should have been a new one

for Arginine:
Human Growth Hormone (HGH) is produced, stored and secreted by the pituitary gland located at the base of the brain. It is a hormone that is widely known for its powerful anabolic (muscle building) effects as well as its lipotropic (breakdown and utilization of body fat) effects. The overall result of these effects is an increase in lean tissue mass and a decrease in body fat.

There are five ways that have been documented in the scientific literature to increase the circulating blood levels of Human Growth Hormone.

First, the amino acid Arginine was been shown to increase circulating levels of HGH after both injection (1) and oral administration (2). The drawback with the use of arginine is that very high doses, over 10 grams daily, were needed to achieve the increase in HGH. Before recommending this it would be important to determine the side effects of prolonged supplementation with mega doses of arginine. There are suggestions that bone growth, especially in the forehead area could be a potentially negative consequence.

Second, similar to arginine, its amino acid metabolite ornithine has been shown to elevate HGH levels after both injection (3) and oral supplementation (4). Again, large amounts were necessary (12 grams) and dosages of this size were seen to immediately cause diarrhea and moderate to severe stomach cramps. Based on this and the possibility of more serious, hidden, long term side effects the use of mega doses of ornithine cannot be recommended.

1. Merimee, T.J.; Rabinowitz, D. and Fineberg, S.E. Arginine-initiated release of human growth hormone. New England Journal of Medicine, 1969, 280, 1434-1438.

2. Pearson, D. and Shaw, S. Life Extension: A Practical Scientific Approach, Warner Press, New York, N.Y., pg.477.

3. Evain-Brion, D.; Donnadieu, M.; Roger, M. and Job, J.C. Simultaneous study of somatotropic and corticotropic pituitary secretions during ornithine infusion test. Clinical Endocrinology, 1982, 17, 119-122.

4. Bucchi, L.; Hickson, J.F.; Pivarnik, J.M.; Wolinsky, I.; McMahon, J.C. and Turner, S.D. Ornithine ingestion and growth hormone release in bodybuilders. Nutrition Research, 1990, 10, 239-245.
 
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